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1.
Sage Open ; 13(2): 21582440231181382, 2023.
Article in English | MEDLINE | ID: mdl-37362766

ABSTRACT

Opportunity areas are primarily selected to improve the social mobility of citizens using education. This paper explores teachers' perspectives on school transitions, particularly emphasizing the role of school transition intervention activities in supporting students' resilience, behavior, academic understanding, and positive parental involvement. Informed by Multiple and Multi-dimensional Transitions (MMT) theory, the paper focuses on the outcomes of school transition intervention activities applied to new Year 7 students in a UK opportunity area. Data was collected through document review, teacher survey, and semi-structured interviews. As a result, 14 interventions were identified, such as a summer school program, peer mentoring, and interschool visits, aiming to make primary to secondary school transition smoother. However, the findings suggested that many schools did not employ some of the school transition intervention projects. Moreover, the data indicated that the COVID-19 pandemic negatively affected the implementation of many of the school transition projects. The paper contributes to understanding the impact of school transition projects on students' confidence, wellbeing, and academic achievement.

2.
Int Health ; 15(3): 309-317, 2023 05 02.
Article in English | MEDLINE | ID: mdl-35713982

ABSTRACT

BACKGROUND: Soil-transmitted helminths (STHs) pose a formidable health risk to school-age children in resource-limited settings. Unfortunately, mass deworming campaigns have been derailed since the onset of the coronavirus disease 2019 pandemic. The present study assessed the cross-sectional associations between STHs, nutritional status and academic performance of schoolchildren in the Banda District of Ghana. METHODS: Schoolchildren (5-16 y of age; n=275) were recruited through both school and household visits by community health workers using a multistage cluster sampling technique. In addition to school microscopy, anthropometric records were also taken. RESULTS: The prevalence of geohelminthiasis was 40.4% (95% confidence interval 34.6 to 46.2). STHs targeted for elimination by the World Health Organization and national programmes were detected among schoolchildren. Children with intestinal parasite infection (53.7 [standard deviation {SD} 11.5]) had lower mean academic scores compared with uninfected children (59.6 [SD 16.9]) (p=0.034). In multiple regression analysis, intestinal parasite infection status and z-scores for weight-for-age showed a collective significant effect on the academic score (F1117=8.169, p<0.001, R2=0.125). CONCLUSIONS: Schoolchildren with STHs had poorer academic performance compared with uninfected children, despite their nutritional status. In addition to school feeding programmes, school-based mass drug administration campaigns may be critical for improving learning outcomes in young schoolchildren.


Subject(s)
COVID-19 , Helminthiasis , Helminths , Intestinal Diseases, Parasitic , Child , Animals , Humans , Cross-Sectional Studies , Helminthiasis/complications , Helminthiasis/epidemiology , Intestinal Diseases, Parasitic/complications , Intestinal Diseases, Parasitic/epidemiology
3.
Stud Health Technol Inform ; 292: 107-110, 2022 May 16.
Article in English | MEDLINE | ID: mdl-35575858

ABSTRACT

To pursue scientific goals with patient data usually requires informed consent from the data subjects. Such a consent constitutes a contract between the research institute and the patient. Several issues must be included in the consent to be valid, for example, how the data is processed and stored as well as specifics of the research questions for which the data is going to be used. Here, we describe the development and the implementation of a user-friendly IT solution that supports the process-oriented obtainment of consents. Current solutions often focus only on the benefits for the researcher. Our solution intends to add value to all participants and to reduce paperwork to a minimum. The consent Tool was evaluated by a usability test using the UEQ Method (User Experience Questionnaire) and received positive feedback - both efficiency and originality were rated above the average UEQ-Benchmark. Nevertheless, the lack of compatibility with the technical infrastructure of the hospital was a significant shortcoming. Hence, although there is a general interest in digitized solutions in the healthcare sector, there are still many hurdles to implement them and roll them out.


Subject(s)
Informed Consent , Research Design , Humans , Research Personnel , Surveys and Questionnaires
4.
Can J Surg ; 65(2): E264-E265, 2022.
Article in English | MEDLINE | ID: mdl-35396268

ABSTRACT

Recent years have seen considerable increases in both the demand for, and complexity of, ventral hernia repairs. This has led to calls for abdominal wall surgery to become a recognized subspecialty in the United States and Europe, with some centres responding by forming specialized, multidisciplinary teams for abdominal wall reconstruction. At present, however, no Canadian city has followed suit. In this article, we outline the major arguments underlying the drive toward the centralization of complex abdominal wall services.


Subject(s)
Abdominal Wall , Hernia, Ventral , Abdominal Wall/surgery , Canada , Hernia, Ventral/surgery , Herniorrhaphy , Humans , Surgical Mesh , United States
5.
J Plast Reconstr Aesthet Surg ; 75(2): 674-682, 2022 Feb.
Article in English | MEDLINE | ID: mdl-34753685

ABSTRACT

BACKGROUND: Indocyanine green fluorescence angiography (ICGFA) is a technique for assessing vascularity and perfusion which has multiple proven applications across a variety of surgical procedures. Studies have been performed assessing its potential role in evaluating skin flap viability in complex abdominal wall reconstruction (CAWR) in order to avoid postoperative surgical site occurrences (SSO). OBJECTIVES: This scoping review was intended to summarise the literature concerning ICGFA in CAWR in order to facilitate future evidence-based guidelines for its use. ELIGIBILITY CRITERIA: Inclusion - cohort studies, randomised controlled trials, case series, case reports and ventral midline hernias only. Exclusion - patients aged under 18 years and non-human test subjects. SOURCES OF EVIDENCE: PubMed, MEDLINE®, Cochrane, Embase and OpenGrey RESULTS: A total of 3416 unique titles were yielded from our search of which 9 met our inclusion criteria: 3 case reports, 1 retrospective case series, 1 prospective case series, 3 non-blinded, non-randomised retrospective case-controlled studies and 1 prospective, double-blinded randomised controlled study. The included studies varied considerably in size and method however the consensus appeared to support ICGFA as being a safe and feasible means of assessing tissue flap vascularity in CAWR. The studies returned contrasting results regarding the impact of ICGFA in predicting and avoiding SSOs however there were insufficient numbers of studies for a meta-analysis. CONCLUSIONS: We identify three case reports and four lower quality studies suggesting a possible application for ICGFA in CAWR and two higher quality studies showing no overall benefit. Evidence-based guidelines on the role of ICGFA in CAWR will require the assessment of further studies.


Subject(s)
Abdominal Wall , Abdominoplasty , Hernia, Ventral , Abdominal Wall/diagnostic imaging , Abdominal Wall/surgery , Abdominoplasty/methods , Adolescent , Aged , Fluorescein Angiography/methods , Hernia, Ventral/surgery , Humans , Indocyanine Green , Randomized Controlled Trials as Topic , Retrospective Studies
6.
Sex Health ; 18(5): 413-420, 2021 11.
Article in English | MEDLINE | ID: mdl-34742364

ABSTRACT

Background Chlamydia trachomatis (chlamydia) is highly prevalent and is an important sexually transmitted infection as it can lead to increased risk of HIV seroconversion; and if left untreated, can cause infertility in women. Clinical guidelines recommend treating chlamydia presumptively when presenting symptomatically; however, clinicians are now questioning this due to increasing prevalence of antimicrobial resistance. Methods To determine the accuracy of presumptive chlamydia treatment practices at a walk-in sexual health service in regional Australia, we audited all same-day screen and treat presentations prescribed azithromycin over a 6-month period in 2018. Results A total of 325 cases were included in the analysis. Over half (54%) the presentations returned negative pathology for all pathogens investigated. One quarter (25%) of presentations were positive for chlamydia, and (4%) reported a dual infection. A further one fifth (20%) were negative for chlamydia but positive for another pathogen. More symptomatic males than females returned positive pathology for chlamydia (8% vs 4%). Conclusions While presumptive treatment is recommended in the current guidelines, our findings indicate this resulted in over-treatment. Considering the increasing resistance patterns for Mycoplasma genitalium, which include azithromycin, presumptive treatments need to balance immediate client care needs against long-term community antimicrobial resistance outcomes. This internal audit provided a feedback mechanism to the walk-in sexual service, enabling modification of practices to provide more precise, individual clinical care within the bounds of current STI guidelines, while balancing wider the objectives of antimicrobial stewardship.


Subject(s)
Chlamydia Infections , Mycoplasma Infections , Mycoplasma genitalium , Chlamydia Infections/diagnosis , Chlamydia Infections/drug therapy , Chlamydia Infections/epidemiology , Chlamydia trachomatis , Clinical Audit , Female , Health Services , Humans , Male , Mycoplasma Infections/epidemiology , Prevalence
7.
Can J Surg ; 60(6): E6-E7, 2017 12.
Article in English | MEDLINE | ID: mdl-29173264
8.
Can J Surg ; 60(4): 247-252, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28562235

ABSTRACT

BACKGROUND: We recently studied attrition in Canadian general surgical programs; however, there are no data on whether residents enrolled in other surgical residencies harbour the same intents as their general surgical peers. We sought to determine how many residents in surgical disciplines in Canada consider leaving their programs and why. METHODS: An anonymous survey was administered to all residents in 9 surgical disciplines in Canada. Significance of association was determined using the Pearson χ2 test. The Canadian Post-MD Education Registry (CAPER) website was used to calculate the response rate. RESULTS: We received 523 responses (27.6% response rate). Of these respondents, 140 (26.8%) were either "somewhat" or "seriously" considering leaving their program. Residents wanting to pursue additional fellowship training and those aspiring to an academic career were significantly less likely to be considering changing specialties (p = 0.003 and p = 0.005, respectively). Poor work-life balance and fear of unemployment/underemployment were the top reasons why residents would change specialty (55.5% and 40.8%, respectively), although the reasons cited were not significantly different between those considering changing and those who were not (p = 0.64). Residents who were considering changing programs were significantly less likely to enjoy their work and more likely to cite having already invested too much time to change as a reason for continuing (p < 0.001). CONCLUSION: More than one-quarter of residents in surgical training programs in Canada harbour desires to abandon their surgical careers, primarily because of unsatisfactory work-life balance and limited employment prospects. Efforts to educate prospective residents about the reality of the surgical lifestyle and to optimize employment prospects may improve completion rates.


CONTEXTE: Nous avons récemment étudié les taux d'attrition dans les programmes de chirurgie générale canadiens; toutefois, on ne dispose pas de données pour déterminer si les résidents inscrits dans d'autres programmes de chirurgie ont les mêmes intentions que leurs collègues de chirurgie générale. Nous avons voulu savoir combien de résidents des disciplines chirurgicales au Canada envisagent de quitter leur programme et pourquoi. MÉTHODES: Tous les résidents de 9 disciplines chirurgicales au Canada ont passé un sondage anonyme. La portée de la corrélation a été déterminée à l'aide du test χ2 de Pearson. Le site Web du Répertoire canadien sur l'éducation post-MD (RCEP) a été utilisé pour calculer le taux de réponse. RÉSULTATS: Nous avons reçu 523 réponses (taux de réponse de 27,6 %). Parmi les répondants, 140 (26,8 %) envisageaient « peut-être ¼ ou « sérieusement ¼ de quitter leur programme. Les résidents qui souhaitaient suivre une formation de surspécialité et ceux qui aspiraient à une carrière universitaire étaient notablement moins susceptibles d'envisager un changement de programme (p = 0,003 et p = 0,005, respectivement). Les problèmes de conciliation travail-famille et la crainte du chômage ou du sous-emploi ont été les principales raisons invoquées par les résidents pour changer de spécialité (55,5 % et 40,8 %, respectivement), même si les raisons citées n'étaient pas sensiblement différentes selon que les répondants envisageaient ou non un tel changement (p = 0,64). Les résidents qui envisageaient un changement de programme étaient notablement moins susceptibles d'apprécier leur travail et plus susceptibles d'invoquer le considérable investissement de temps déjà consenti comme raison pour ne pas changer de programme (p < 0,001). CONCLUSION: Plus du quart de résidents des programmes de formation en chirurgie au Canada souhaitent abandonner leur carrière en chirurgie, principalement en raison des problèmes de conciliation travail-famille et des perspectives d'emploi limitées. Des efforts pour renseigner les candidats sur ce que représente réellement la vie de chirurgien et pour optimiser les perspectives d'emploi pourraient améliorer les taux d'achèvement des programmes.


Subject(s)
Attitude of Health Personnel , Career Choice , Internship and Residency/statistics & numerical data , Physicians/statistics & numerical data , Specialties, Surgical/statistics & numerical data , Adult , Canada , Humans
9.
Obes Surg ; 25(5): 777-81, 2015 May.
Article in English | MEDLINE | ID: mdl-25416083

ABSTRACT

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a well-recognised complication of obesity. One of the microvascular complications of T2DM is diabetic retinopathy (DR). Bariatric surgery has been shown to effectively treat obesity and can induce remission of T2DM. It is not known what effect this improvement may have on pre-existing DR. We aimed to investigate this. METHOD: A dual-centre, observer-blinded, case-control study investigated the progression of DR in patients who received Roux-en-Y gastric bypass (treatment group (TG)), compared with controls who received medical therapy (control group (CG)) for their T2DM. Retinal images were taken pre-operatively and approximately 2 years post-operatively for the TG and over a 2-year interval for the CG. Data were collected for confounding variables, including glycaemic control (HbA(1c)) and BMI. RESULTS: Forty-five patients were recruited (TG = 21, CG = 24). Groups were significantly heterogeneous. DR showed significant progression for those in the CG (p = 0.03) but not in TG (p = 0.135), no significant difference was found when adjusting for confounding variables (p = 0.480). There was a significant trend in favour of surgery in improvement of glycaemic control (p = 0.017). CONCLUSION: The trends within these pilot data may represent a real difference in the progression of DR in patients who have received surgery, compared with medical treatment alone. Due to heterogeneity of group characteristics, further work needs to be done to validate these results. Should there be a true difference, there will be potential cost savings for the National Health Service (NHS) along with a reduced burden of disease for patients.


Subject(s)
Diabetes Mellitus, Type 2/surgery , Diabetic Retinopathy/surgery , Gastric Bypass , Obesity/surgery , Aged , Aged, 80 and over , Diabetes Mellitus, Type 2/complications , Diabetic Retinopathy/etiology , Disease Progression , Female , Gastric Bypass/methods , Humans , Male , Middle Aged , Obesity/complications , Pilot Projects , Retrospective Studies , Single-Blind Method , Treatment Outcome
10.
Postgrad Med J ; 89(1053): 411-6; quiz 415, 416, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23472004

ABSTRACT

Obesity has become an increasingly important health problem over the past 30 years. Presently around a quarter of the UK adult population are obese and this figure is set to increase further in the coming decades. The health consequences of obesity on multiple body systems have been well established as has the financial cost of the condition to both the individuals affected as well as to society as a whole. Bariatric surgery has been shown to be the only long term effective solution in terms of sustained weight loss and comorbidity resolution. The commonest bariatric procedure in the UK is the Roux-en-y gastric bypass which consistently results in the loss of 70%-80% of excess bodyweight. Results however are variable and in order to optimise resource allocation and avoid exposing patients unlikely to benefit from surgery to its inherent risks, much research has been done to try to identify those patients most likely to obtain a good result. The only factor which has been subjected to meta-analysis is that of preoperative weight loss which shows a positive association with postoperative weight loss following bypass surgery. Although the remaining data are not based on level 1 evidence those other preoperatively identifiable factors which are associated with an improved outcome include Caucasian or Hispanic ethnicity, higher educational status, non-shift-work working patterns, female gender and divorced or single marital status. Similarly increased levels of preoperative physical activity and an absence of binge eating behaviour are consistent with a favourable result whereas increased age, smoking and other socioeconomic factors have not been shown to have a significant impact. Conversely diabetes mellitus seems to have a slight negative correlation with postoperative weight loss; however, a history of sexual abuse or psychiatric illness has not been shown to have a lasting influence.


Subject(s)
Feeding and Eating Disorders/epidemiology , Gastric Bypass/methods , Obesity, Morbid/epidemiology , Obesity, Morbid/surgery , Preoperative Period , Smoking/epidemiology , Weight Loss , Adult , Body Mass Index , Comorbidity , Feeding and Eating Disorders/complications , Female , Gastric Bypass/statistics & numerical data , Humans , Male , Middle Aged , Motor Activity , Postoperative Period , Predictive Value of Tests , Reference Values , Smoking/adverse effects , Socioeconomic Factors , Treatment Outcome , United Kingdom/epidemiology
11.
Blood Press ; 22(3): 131-7, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23244451

ABSTRACT

It is well established that hypertension and obesity appear to be associated. The exact mechanism by which they are linked is unclear and remains a topic of a great deal of research. Current NICE guidelines recommend that patients with a BMI in excess of 35 kg/m(2) should be considered for bariatric surgery if they have a concomitant obesity-associated condition, of which hypertension is one. The commonest bariatric procedure in the UK is the Roux-en-Y gastric bypass, which has been shown to result in long-standing remission of hypertension in up to 93% of patients. This paper summarizes the existing literature on the main theories as to how obesity leads to hypertension as well as the literature concerning the effects of gastric bypass surgery on hypertension.


Subject(s)
Gastric Bypass/methods , Hypertension/etiology , Obesity/complications , Obesity/surgery , Body Mass Index , Gastric Bypass/adverse effects , Humans
12.
Am Surg ; 78(4): 408-13, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22472396

ABSTRACT

Clostridium difficile infection is associated with substantial morbidity and mortality, increased duration of hospitalization, and a marked economic impact. Several case reports and case series have described C. difficile infection in excluded bowels or immediately after reversal of defunctioning ileostomy. The aim of this prospective study is to detect whether the excluded colon is associated with a higher rate of C. difficile colonization than the normal population, which may increase the risk of C. difficile infection. Patients with defunctioning loop ileostomy, undergoing closure of ileostomy to restore bowel continuity, were prospectively recruited. Two stool samples were collected from the ileostomy effluent before closure of ileostomy and two after the procedure including the first bowel movement. All samples were cultured for C. difficile and analyzed for toxins A and B by a Premier EIA test. Demographic data and possible confounding factors were observed and recorded. Twenty-fine adult patients were recruited to this study; five patients were subsequently excluded. Two patients had positive stool cultures for C. difficile in the postoperative samples and another patient developed clinical pseudomembranous colitis with positive toxin. This indicates a possible colonization rate of 3 to 38 per cent (95% confidence interval). Four observed cases out of the 20 subjects taking part in this study would confidently conclude that C. difficile colonization in the excluded colon is 6 to 44 per cent, i.e., higher than the incidence in the healthy adult population, which is 3 per cent. However, the findings of this study prompt larger and well-powered studies to confirm these findings.


Subject(s)
Clostridioides difficile/isolation & purification , Colon/microbiology , Ileostomy , Adult , Aged , Aged, 80 and over , Enterocolitis, Pseudomembranous/etiology , Feces/microbiology , Female , Humans , Male , Middle Aged , Pilot Projects , Postoperative Complications/microbiology , Prospective Studies
13.
BMJ ; 344: d8312, 2012 Jan 16.
Article in English | MEDLINE | ID: mdl-22250218
14.
Aust N Z J Obstet Gynaecol ; 51(6): 527-31, 2011 Dec.
Article in English | MEDLINE | ID: mdl-21806597

ABSTRACT

BACKGROUND: Emergency contraception (EC) has been available as a Schedule 3 (over-the-counter, OTC) medication through Australian pharmacies since 2004. This study aimed to describe OTC EC dispensing services in pharmacies in the Cairns and Hinterland Health Service District and to explore the knowledge and attitudes of pharmacy staff. The study findings will assist in developing resources to support pharmacy staff in their OTC EC provision role. STUDY DESIGN: We conducted semi-structured interviews with pharmacy managers and pharmacists to determine the availability, cost, dispensing processes and distribution estimates of EC and anonymous surveys of pharmacy staff to examine their knowledge and attitudes. RESULTS: Forty-six (88%) of the 52 local pharmacies participated; 43 (93%) provide OTC EC at an average cost of $28.95. One hundred and forty-five staff surveys were completed. Few pharmacists identified Family Planning Queensland (FPQ) or the Cairns Sexual Health Service (CSHS) as referral options for women not meeting the dispensing criteria. A range of written information is provided to EC customers by 23 (53%) of pharmacies. CONCLUSIONS: This study has documented OTC EC dispensing services in the District and identified areas for improvement. A working group has been established to oversee the development and distribution of customer information packs and information for pharmacists on referral options.


Subject(s)
Attitude of Health Personnel , Contraceptives, Postcoital/supply & distribution , Health Knowledge, Attitudes, Practice , Nonprescription Drugs/supply & distribution , Pharmacists , Adult , Checklist , Contraceptives, Postcoital/economics , Family Planning Services , Female , Humans , Interviews as Topic , Male , Middle Aged , Nonprescription Drugs/economics , Patient Education as Topic , Pharmacies , Queensland , Referral and Consultation , Rural Health Services , Urban Health Services , Young Adult
17.
J Med Ethics ; 37(8): 476-8, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21478425

ABSTRACT

Point-of-care testing (POCT) is a sensitive, specific and rapid form of testing for the presence of HIV antibodies. Post-exposure prophylaxis for HIV infection can reduce seroconversion rates by up to 80%. Needlestick injuries are the second commonest cause of occupational injury in the NHS and 20% of these occur during operations. In the NHS, in order to protect staff and patients from the risk of bloodborne viruses such as HIV, it is mandatory to report such injuries; however, numerous studies have shown that many groups, particularly doctors, are reluctant to do so. This article outlines the arguments for and against the introduction of preoperatively seeking consent from patients to have their blood tested for HIV via POCT in order to improve the reporting rates of needlestick injuries incurred during surgery and to protect staff from infection.


Subject(s)
HIV Infections/diagnosis , Infectious Disease Transmission, Patient-to-Professional , Needlestick Injuries/complications , Occupational Diseases/prevention & control , Point-of-Care Systems/ethics , HIV Infections/prevention & control , HIV Infections/transmission , Hematologic Tests/ethics , Humans , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Occupational Exposure , Patient Acceptance of Health Care , Post-Exposure Prophylaxis , Virus Diseases/diagnosis , Virus Diseases/prevention & control , Virus Diseases/transmission
18.
Occup Med (Lond) ; 60(2): 139-44, 2010 Mar.
Article in English | MEDLINE | ID: mdl-20064896

ABSTRACT

BACKGROUND: Needlestick injuries are common during surgical procedures. Following such an injury, local protocols should be followed to minimize the risk of infection. AIMS: To identify who sustains such injuries, under what circumstances and what actions are taken to minimize the risk and in response to intraoperative needlestick injuries. METHODS: A questionnaire was submitted via e-mail to all staff in a National Health Service trust who took part in operations. The results were checked against occupational health department (OHD) records. RESULTS: One hundred and thirty-six of 255 appropriate responders completed the questionnaire (53%). Fifteen of 31 consultants (48%), 12/36 junior doctors (33%), 0/39 midwives (0%) and 8/30 theatre staff (27%) reported having had at least one intraoperative needlestick injury over the past year. Awareness of local protocols was significantly worse in the junior doctor group. Ninety-three percent of consultants, 67% of junior doctors and 13% of theatre staff did not comply with local protocols. The length of time it takes to do so (48%) and a perceived low infection risk of the patient (78%) were the commonest reasons for this. Hand dominance, role during surgery and double gloving were not significant risk factors; however, rare use of a no-touch technique was. Comparison with OHD records suggested that a maximum of 16% of intraoperative needlestick injuries were dealt with in accordance to local policy. CONCLUSIONS: Non-compliance with needlestick injury protocols is commonest among senior surgical staff. A revision of the protocol to reduce the time it takes to complete it may improve compliance.


Subject(s)
Accidents, Occupational/statistics & numerical data , Health Knowledge, Attitudes, Practice , Needlestick Injuries/epidemiology , Personnel, Hospital/statistics & numerical data , Safety Management/organization & administration , Accidents, Occupational/prevention & control , Accidents, Occupational/psychology , Gloves, Surgical/statistics & numerical data , Guideline Adherence , Humans , Internet , Needlestick Injuries/prevention & control , Needlestick Injuries/psychology , Personnel, Hospital/psychology , Risk Factors , State Medicine/statistics & numerical data , Surgical Procedures, Operative , Surveys and Questionnaires , Time Factors , Truth Disclosure , United Kingdom
19.
J Med Case Rep ; 3: 6442, 2009 Mar 10.
Article in English | MEDLINE | ID: mdl-19830102

ABSTRACT

INTRODUCTION: Silicone lymphadenopathy is a rare but recognised complication of procedures involving the use of silicone. It has a poorly understood mechanism but is thought to occur following the transportation of silicone particles from silicone-containing prostheses to lymph nodes by macrophages. CASE PRESENTATION: We report of a case involving a 35-year-old woman who presented to the breast clinic with a breast lump and altered sensation below her left nipple 5 years after bilateral cosmetic breast augmentations. A small lump was detected inferior to the nipple but clinical examination and initial ultrasound investigation showed both implants to be intact. However, mammography and magnetic resonance imaging of both breasts revealed both intracapsular and extracapsular rupture of the left breast prosthesis. The patient went on to develop a flu-like illness and tender lumps in the left axilla and right mastoid regions. An excision biopsy of the left axillary lesion and replacement of the ruptured implant was performed. Subsequent histological analysis showed that the axillary lump was a lymph node containing large amounts of silicone. CONCLUSION: The exclusion of malignancy remains the priority when dealing with lumps in the breast or axilla. Silicone lymphadenopathy should however be considered as a differential diagnosis in patients in whom silicone prostheses are present.

20.
BMJ Case Rep ; 20092009.
Article in English | MEDLINE | ID: mdl-21686552

ABSTRACT

A 73-year-old woman underwent an uncomplicated focused parathyroidectomy for an adenoma. Immediately after extubation she developed respiratory distress and her airway became compromised. No obvious cause could be found for the stridor and no response was obtained from nebulised adrenaline (norepinephrine). An intravenous bolus of calcium provided immediate but temporary relief. Lasting relief was obtained following the administration of an intravenous calcium infusion. Serology later confirmed a small decrease in calcium concentrations but at the time of the respiratory compromise the values were still within normal range.

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