[Use of radioisotopes in the evaluation of coronary disease]. / Uso dei radioisotopi nella valutazione della cardiopatia coronarica.

A study on myocardial perfusion through scintigraphy with 201-Tl has been carried on in a group of 57 persons: among them 45 had myocardial infarction and 12 had myocardial ischemia in act. In consideration of this experience, the myocardial scintigraphy with 201-Tl seems to be a valid investigation method to support the electro-vectocardiography when evaluating, bloodlessly, ischemical cardiopathies. In general, the correlation between electro-vectorcardiographic and scintigraphic data has been satisfactory. Referring to stroken parts, we can say that also those cardiac sectors usually very difficult to be explored with other radio elements such as 131-CS and 42-K, have been adequately studied with 201-Tl. To sum up, we can say that scintigraphic investigation of myocardium with 201-Tl is certainly a valid blood-less method to diagnose ischemical cardiopathy with the advantage to be also a useful diagnostical element for the evaluation of the microcirculation.

[The significance of the radioimmunological of serum myoglobin in myocardial infarction]. / Significato della valutazione radioimmunologica della mioglobinemia in corso di infarto miocardico.

The Authors carried on a study in a group of 31 patients with acute myocardial infarction (AMI). The controled particularly the following dates: myoglobinemia (MG) with RIA and myocardial necrosis enzymes with traditional methods. Blood has been drawn from patients every 90 min, during the first 8 h of admission and every 4 h during the following 4 days. Important variations of MG have been detected in 80.6% of cases. These is an early increase in MG (within 4 h in 25.8% and within 8 h in 45.1% of cases) and normal values are reached in a time not longer the 72 h. The maximum value is reached in a shorter time than that creatine phosphokinase (CPK). We can therefore confirm that MG is a useful data in the early diagnosis of myocardial infarction in preenzymatic stage.

[Possible correlations between kidney movement and hypertension (author's transl)]. / Possibili correlazioni fra mobilita' renale ed ipertensione.

The authors report the first data relating to their research carried out with the intention of showing the possible correlations between pathological kidney movement and so-called essential hypertension. The study of the kidneys has been carried out with 99mTc-DMSA, using multiple projections both in upright and prone positions. Furthermore, the appropriate renogram has been carried out for each patient. In the light of the obtained data the AA. point that in the majority of hypertensive patients personally examined (80.5%) there was a pathological renal movement, most often bilateral (22%) or affecting the right kidney (17.1%), with which variations were often associated, especially in the second stage of the renograph. The authors underline the importance of this type of investigation, which will be further extended by the associated use of 99mTc-Ca-Glucoheptonate.