A review of preclinical evidence of Cryptolepis nigrescens (Wennberg) L. Joubert. and Bruyns., Prosopsis africana (Guill. and Perr.) Taub. and Pterygota macrocarpa K. Schum. traditionally used to manage tumours in Ghana.

ETHNOPHARMACOLOGICAL RELEVANCE: Cancer stands as one of the leading causes of death worldwide according to the World Health Organization (WHO), and it has led to approximately 10 million fatalities in 2020. Medicinal plants are still widely used and accepted form of treatment for most diseases including cancer in Ghana. This review presented Cryptolepis nigrescens (Wennberg) L. Joubert. and Bruyns., Prosopsis africana (Guill. and Perr.) Taub. and Pterygota macrocarpa K. Schum. as medicinal plants that are traditionally used to treat tumour growth, amongst other diseases, in the Ashanti region of Ghana. AIM OF REVIEW: This paper aims to present a comprehensive review on the botanical description, ecological distribution, ethnomedicinal uses, phytochemical composition and ethnopharmacological relevance of C. nigrescens, P. africana and P. macrocarpa. MATERIALS AND METHODS: The review covers works published between 1962 and 2023 from various countries. Published books, thesis, scientific and medical articles on C. nigrescens, P. africana and P. macrocarpa were collected from the following databases: 'Scopus', 'Science Direct', 'Medline', 'PubMed', 'Research Gate' 'Google Scholar, and 'Springer link' using the keywords. RESULTS: Phytochemical analysis of C. nigrescens, P. africana and P. macrocarpa revealed the presence of some prominent bioactive compounds such as convallatoxin, 7,3,4-trihydroxy-3-methoxyflavanone and dioxane, respectively. Plant extracts and isolated compounds of these medicinal plants exhibited a wide range of ethnopharmacological activities including antimicrobial, anti-inflammatory, antioxidant, analgesic, cytotoxic, antimalarial, antipyretic, haematinic, hepato-protective, aphrodisiac and antihypertensive properties. CONCLUSION: The present review on C. nigrescens , P.africana and P. macrocarpa provided a credible summary of the ethnopharmacological research conducted on these medicinal plants till date. The data also highligted the potential therapeutic profiles of these plants in Ghana that could serve as foundation for future studies. Additionally, the information significantly supported the traditional and commercial use of these plants among the people.

Mining-induced changes in ecosystem services value and implications of their economic and relational cost in a mining landscape, Ghana.

The surge in mining operations to meet the global demand for mineral resources adversely impacts ecosystem services and dependent households, but the issue barely attracts attention. This study evaluated the dynamics of mining-induced changes in the value of ecosystem services (ES) and the consequent economic and relational cost to rural households in the Ahafo region of Ghana. Face-to-face structured interviews with 200 householders were conducted in three mining communities. We determined relational values in the landscape through focus group discussion and the economic cost of the ecosystem services lost by applying replacement and contingency cost estimations. Old-growth forests, degraded forests, teak plantations, cultivated land, wetlands, and grassland were ecosystems identified in the mining landscape. The most valued ecosystem was old-growth forest, while the least was grassland. Provisioning service was the most valued ES, while supporting service was the least. Provisioning ES was rated the most impacted by the mine, whereas cultural services were the least affected. Mining activities caused a significant loss of 14 ecosystem services (including crops, livestock, capture fisheries, wild food, bush meat, biomass fuel, and freshwater) that were of priority to the communities. The affected households experienced relatively high monthly economic costs, approximating $300 per household, from the loss of priority ecosystem services. Canonical correspondence analysis revealed connections between ecosystem services valuation and the socio-demographic characteristics of the respondents. There was a perceived mine-adverse effect on the relational values of the people relating to cultural identity, sovereignty, symbolic value, security, subsistence and livelihood, sense of place, social cohesion, social memory, female emotional/mental health, and womanhood training opportunities. Actors in the mining industry should consider policies and management interventions that will limit ecosystem services loss, widely ascertain ecosystem benefits, and comprehensively mitigate the impact of their loss on households.

Selective and clear-cut logging have varied imprints on tree community structure in a moist semi-deciduous forest in Ghana.

Logging-induced disturbance can be an important agent of change in tropical forests. Understanding the relative impacts of specific logging regimes on tree community structure is essential for forest management and biodiversity conservation. In this study, we assessed the response of tree community structure to selective and clear-cut logging in a moist semi-deciduous forest in Ghana. We quantified the diversity, composition, density and basal area of trees (diameter at breast height ≥5 cm) in 30 20 × 20 m plots in each of three forest management systems (selectively logged, clear-cut logged, old-growth). Our results showed that the two logged forests harboured significantly lower tree species diversity than the old-growth forest. Nevertheless, the selectively logged forest supported significantly higher tree species diversity than the clear-cut logged forest. Similarly, both logging regimes caused shifts in tree species composition, but the shift was higher in the clear-cut forest than the selectively logged forest, indicating a better recovery in the selective logging stands. Selective and clear-cut logged forests supported similar stem density of trees, but they were lower than that of the old-growth forest. Finally, the old-growth forest exhibited significantly higher basal area than the selectively logged forest, which in turn, had significantly higher basal area than the clear-cut logged forest. Overall, selective logging imprints on tree community structure were lower than clear-cut logging due to faster recovery by the former. Our findings suggest that logged tropical forests may require a long period to fully recover.

Edge disturbance shapes liana diversity and abundance but not liana-tree interaction network patterns in moist semi-deciduous forests, Ghana.

Edge disturbance can drive liana community changes and alter liana-tree interaction networks, with ramifications for forest functioning. Understanding edge effects on liana community structure and liana-tree interactions is therefore essential for forest management and conservation. We evaluated the response patterns of liana community structure and liana-tree interaction structure to forest edge in two moist semi-deciduous forests in Ghana (Asenanyo and Suhuma Forest Reserves: AFR and SFR, respectively). Liana community structure and liana-tree interactions were assessed in 24 50 × 50 m randomly located plots in three forest sites (edge, interior and deep-interior) established at 0-50 m, 200 m and 400 m from edge. Edge effects positively and negatively influenced liana diversity in forest edges of AFR and SFR, respectively. There was a positive influence of edge disturbance on liana abundance in both forests. We observed anti-nested structure in all the liana-tree networks in AFR, while no nestedness was observed in the networks in SFR. The networks in both forests were less connected, and thus more modular and specialised than their null models. Many liana and tree species were specialised, with specialisation tending to be symmetrical. The plant species played different roles in relation to modularity. Most of the species acted as peripherals (specialists), with only a few species having structural importance to the networks. The latter species group consisted of connectors (generalists) and hubs (highly connected generalists). Some of the species showed consistency in their roles across the sites, while the roles of other species changed. Generally, liana species co-occurred randomly on tree species in all the forest sites, except edge site in AFR where lianas showed positive co-occurrence. Our findings deepen our understanding of the response of liana communities and liana-tree interactions to forest edge disturbance, which are useful for managing forest edge.

Phytoremediation of wastewater with Limnocharis flava, Thalia geniculata and Typha latifolia in constructed wetlands.

Phytoremediation is thought to be the most sustainable wastewater treatment option for developing countries. However, its application is often limited by unavailability of suitable candidate species. In the present study, the potentials of Limnocharis flava, Thalia geniculata and Typha latifolia for remediation of heavy metal contaminated wastewater with a constructed wetland system were evaluated. The wetland consisted of three treatment lines each planted with sufficient and equal number of a species. Duplicate plant and water samples were collected bi-monthly and analyzed for Fe, Cu, Zn, Pb, and Hg using the atomic absorption spectrophotometer over a six month period. Bioaccumulation rates generally increased over time and varied among plants for these metals, with Fe (456-1549 mg kg1 roots; 20-183 mg kg(-1) shoot) being the most sequestered and Pb (1.2-7.6 mg kg(-1) roots; 1.55-3.95 mg kg(-1) shoot) the least. Translocation factors differed among the species but generally remained stable over time. L flava showed potential for hyperaccumulating Hg. Removal efficiencies varied for the studied metals (approximately 20-77 %) and were generally related to metal uptake by the plants. These results demonstrate the suitability of the species for phytoremediation, and the usefulness of the technique as an option for improving irrigation water quality in Ghana.