Nuts, vegetables, fruits, and protein dietary pattern during pregnancy is inversely associated with risk of childhood allergies: a case-control study.

Allergic diseases are prevalent chronic conditions among children and can lead to significant health and economic issues. It is hypothesized that healthy and high quality diet during pregnancy can prevent the onset of allergic diseases in offspring. This study aimed to investigate the potential relationship between major dietary patterns during pregnancy and allergies in children under one year of age. This case-control study was conducted involving 244 participants (122 mothers of allergic children and 122 healthy controls) who visited pediatricians and allergy outpatient clinics in Khuzestan Province, Iran, between June 2022 and March 2023. Demographic information was recorded using a socio-demographic questionnaire. A food frequency questionnaire was used to identify the foods consumed during pregnancy. Major dietary patterns were extracted using principal component analysis, and the potential relationship between these patterns and childhood allergies was investigated using multivariable logistic regression models. The crude odds ratio (OR) analysis showed that the fourth quartile of "Nut, vegetables, fruits, and protein" dietary pattern was associated with lower occurrence of childhood allergies (OR: 0.214, 95% CI = 0.068-0.679; P trend = 0.211). After adjusting for cofactors in Model 3, this association was still observed in the fourth quartile (OR = 0.108, 95% CI = 0.019-0.613; P trend, 0.001). However, no significant association was observed between "Carbohydrate and cereals" and "Salty" dietary patterns and childhood allergies. The study findings suggest that a maternal dietary pattern rich in nuts, vegetables, and fruits during pregnancy may reduce the risk of allergic diseases in offspring.

Evaluation of dietary food intakes and anthropometric measures in middle-aged men with aggressive symptoms.

BACKGROUND: Aggression is one of the most prevalent behavioral disorders in men. OBJECTIVE: This study aimed to assess the possible association between dietary intake of food groups and aggression in middle-aged married men. METHODS: This case-control study included 336 participants (168 men with aggressive behaviors and 168 healthy controls) aged 35-55 years. Demographic information was collected using a socio-demographic questionnaire. A food frequency questionnaire was used to investigate the diet group intake last year. Based on the normality of the data distribution, Independent t-tests and Mann-Whitney tests were used to compare quantitative variables between the two groups. Categorical variables were compared between cases and controls using the Chi-squared test. Logistic regression analysis was used to examine the possible association between food intake and aggression. RESULTS: Compared to controls, aggressive men had significantly higher mean weight, height, and waist circumference (WC), p = 0.007, p = 0.001, and p = 0.043, respectively. After adjusting WC, energy intake, and educational level, in Model 1, intake of milk, cheese, poultry, red meat, legumes, egg, fruits, and vegetables had a significant protective role on the occurrence of aggression, (Odd Ratio (OR) = 0.36; 95% (Confidence Interval (CI) = 0.204, 0.670; P = 0.001), (OR = 0.440; 95% CI = 0.284, 0.781; P = 0.005), (OR = 0.621; 95% CI = 0.284, 0.781; P = 0.046), (OR = 0.358; 95% CI = 0.198, 0.647; P = 0.001), (OR = 0.434; 95% CI = 0.243, 0.773; P = 0.005), (OR = 0.411; 95% CI = 0.229, 0.736; P = 0.003), (OR = 0.332; 95% CI = 0.180, 0.614; P < 0.001), (OR = 0.310; 95% CI = 0.168, 0.572; P < 0.001), respectively. CONCLUSIONS: Lower WC and a diet containing high-quality protein, fruits, and vegetables can have a protective role against aggression and are recommended for men with an aggressive mood. This diet can affect plasma levels of tryptophan and, therefore, brain levels of serotonin.