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BMC Res Notes ; 12(1): 475, 2019 Aug 01.
Article in English | MEDLINE | ID: mdl-31370867

ABSTRACT

OBJECTIVES: We study the transmission dynamics of cholera in the presence of limited resources, a common feature of the developing world. The model is used to gain insight into the impact of available resources of the health care system on the spread and control of the disease. A deterministic model that includes a nonlinear recovery rate is formulated and rigorously analyzed. Limited treatment is described by inclusion of a special treatment function. Center manifold theory is used to show that the model exhibits the phenomenon of backward bifurcation. Matlab has been used to carry out numerical simulations to support theoretical findings. RESULTS: The model analysis shows that the disease free steady state is locally stable when the threshold [Formula: see text]. It is also shown that the model has multiple equilibria and the model exhibits the phenomenon of backward bifurcation whose implications to cholera infection are discussed. The results are useful for the public health planning in resource allocation for the control of cholera transmission.


Subject(s)
Cholera/prevention & control , Hospital Bed Capacity/statistics & numerical data , Hospitals/statistics & numerical data , Models, Statistical , Public Health/statistics & numerical data , Cholera/economics , Cholera/epidemiology , Cholera/transmission , Computer Simulation , Developing Countries , Humans , Public Health/economics , Public Health/methods , Vibrio cholerae/pathogenicity , Zimbabwe/epidemiology
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