ABSTRACT
Enhanced Non-communicable Diseases (NCDs) screening efforts are emphasized as opportunities to reduce premature mortalities due to the diseases. Nevertheless, the utilization of NCDs screening is affected by the knowledge of the risk factors. This study aimed to assess the relationship between knowledge of non-communicable diseases risk factors and screening service utilization. This community-based cross-sectional study was conducted among randomly selected adult residents of North Shewa Zone, Oromia Region, Central Ethiopia. Descriptive statistics were used to describe the background variables and multivariable logistic regression analysis was conducted to identify the factors associated with screening utilization. A total of 823 respondents completed the survey. The proportion of screening utilization was found to be 34.5 %; 95 % CI: 31.3, 37.9. Age < 25 [Adjusted Odds Ratio (AOR) = 0.10; 95 % CI: 0.04, 0.25] compared with age above 34, attaining secondary school [AOR = 5.28; 95 % CI: 2.28, 12.21], college/above [AOR = 3.41; 95 % CI: 1.53, 7.61] compared with those who had no formal education, presence of family member/s with NCDs [AOR = 1.85; 95 % CI: 1.14, 3.00] and knowledge of NCDs risk factors [AOR = 11.71; 95 % CI: 7.08, 19.35] were significantly associated with screening utilization. This study found that the use of NCD screening was very low. Knowledge of NCD risk factors was strongly associated with screening utilization. This highlights the importance of improving adult knowledge of noncommunicable disease risk factors in Ethiopia.
ABSTRACT
Opportunistic infections (OIs) in HIV patients are infections that are more common or more severe as a result of HIV-mediated immunosuppression. The advances in the capacity of antiretroviral therapy (ART) have diminished the incidence of OIs. However, even in the ART era, HIV-related OIs continue to be major causes of hospitalization and mortality. Therefore, this study aims to identify time to occurrence, predictors, and patterns of OIs incidence among HIV-positive patients attending ART clinic of Salale University Comprehensive Specialized Hospital, Ethiopia. A retrospective cohort study was conducted between 1st September 2016 and 1st September 2021. All 419 patients diagnosed during the study period were recruited. Data were extracted from both patient medical records and ART logbooks. Stata-16 was used for data analysis. Follow-up time was calculated from the date of HIV diagnosis to the date of OIs occurrence or censoring. Cox proportional hazards regression model was used to identify the predictors of OIs incidence. The total person-time of the follow-up was 8656 person-months of observation. During the follow-up time, 199 (47.49%) of the patients had developed OIs. The incidence rate of OIs was 23 (95%CI: 20, 26) per 1000 person-months of observation. The median OIs free survival time was 36 (95%CI: 31, 40) months. Predictors such as residence, cd4 category, baseline hemoglobin level, ART side effects, isoniazid preventive therapy, and chronic disease comorbidity were significantly predicted OIs incidence. The study area's OIs incidence remained high, requiring prompt action. To reduce the morbidity and mortality associated with OIs, HIV-positive patients with the predictors of rural residence, low CD4 category, low baseline hemoglobin level, ART side effects, not taking IPT, and baseline chronic disease comorbidity necessitate close follow-up and monitoring. Thus, we recommend focused and evidence-informed strategies to address OIs burden and improve outcomes.
