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1.
Anal Bioanal Chem ; 389(3): 763-7, 2007 Oct.
Article in English | MEDLINE | ID: mdl-17676313

ABSTRACT

A method for determining plasma power in rf-GDOES is presented. It is based on an effective resistance located in the inductive coil of the impedance matching. The amount of electrical power consumed in the matching system depends on the capacitive current flowing through the matching system, which depends on the applied voltage, the stray capacity, and the frequency. This correction method is experimentally evaluated and compared with the integral plasma power calculation.

2.
Cytokine ; 4(3): 232-8, 1992 May.
Article in English | MEDLINE | ID: mdl-1498258

ABSTRACT

Transforming growth factor beta (TGF-beta) is a multifunctional homodimeric polypeptide with potent actions upon many target cells, including those of mesenchymal and haemopoietic lineage. The recent reports of high levels of the cytokine in rheumatoid synovium and synovial fluid, prompted this study into the effect of intra-articular injection of TGF beta-2 into rabbit knee-joints. Four daily injections of 1 microgram caused swelling, probably as a consequence of prostaglandin E2 production, synovial fibroblastic hyperplasia and a striking loss of femoral condyle proteoglycan. Using the polymerase chain reaction, no evidence could be obtained for the induction of interleukin-1 alpha gene expression in either synovial tissue or synovial fluid cells. These findings suggest that the TGF-beta present in the rheumatoid joint may contribute directly to the pathogenesis of rheumatoid arthritis.


Subject(s)
Arthritis/chemically induced , Proteoglycans/metabolism , Transforming Growth Factor beta/toxicity , Animals , Cartilage, Articular/drug effects , Cartilage, Articular/metabolism , Dinoprostone/biosynthesis , Edema/chemically induced , Hyperplasia , Injections, Intra-Articular , Interleukin-1/biosynthesis , Polymerase Chain Reaction , Rabbits , Recombinant Proteins/administration & dosage , Recombinant Proteins/toxicity , Synovial Membrane/pathology , Transforming Growth Factor beta/administration & dosage
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