ABSTRACT
The blood serum, liver, cerebral and pancreatic tissues of 250 rats aged 1 to 1.5 mos. were investigated. Alloxan diabetes caused profound changes in the lipid composition of various tissues, the most noticeable ones in the pancreas. Of all easily assimilable carbohydrates used as admixtures to a common ration fructose followed by xylite and sorbitol produced the most unfavorable effect on lipid metabolism. The best results were obtained by adding up glucose.
Subject(s)
Diabetes Mellitus, Experimental/metabolism , Dietary Carbohydrates/administration & dosage , Lipid Metabolism , Animals , Brain/metabolism , Liver/metabolism , Pancreas/metabolism , RatsABSTRACT
The influence of readily available carbohydrates (sugar, xylitol and sorbitol) on the metabolic processes was studied in 80 children with diabetes mellitus. It was found that even low doses (20 g) of sorbitol and xylitol produced an unfavourable effect on the lipid metabolism and liver function. It is recommended that low doses (20 g) of sugar be included into the diet for children with diabetes mellitus.
Subject(s)
Diabetes Mellitus, Type 1/diet therapy , Sorbitol/therapeutic use , Sucrose/therapeutic use , Xylitol/therapeutic use , Adolescent , Blood Glucose/analysis , Child , Combined Modality Therapy , Diabetes Mellitus, Type 1/blood , Humans , Lipids/blood , Sorbitol/adverse effects , Xylitol/adverse effectsABSTRACT
A procedure for running sessions of hyperbaric oxygenation in the treatment of children suffering from diabetes mellitus, was developed. A high efficacy of the method was established, particularly for such complications as angiopathy, polyneuritides, trophic changes of tissues.