[Factors in the development of chronic infection foci in the nasopharynx]. / Vyvchennia faktoriv rozvytku khronichnykh vohnyshch infektsiï v nosohlottsi.

Antigens were studied of HLA system in always ailing patients presenting with the formed chronic focus of infection in the tonsils. A total of 56 patients with chronic decompensated tonsillitis who were assigned for tonsillectomy by clinical indications were examined together with 53 essentially healthy subjects. Tonsillitis patients revealed HLA-antigens B7, A1, associations A10B7, more frequently than controls, the difference being statistically significant. The data obtained are helpful in identification of risk groups in relation to formation in recurrent respiratory diseases of chronic focal pathology in the nasopharynx.

[The effect of lymphocytic chalone on lymphocyte functional activity in antioxidant deficiency and its correction with vitamin E]. / Vplyv limfotsytarnoho keilonu na funktsiinu aktyvnist' limfotsytiv pry antyoksydantnii nedostatnosti ta korektsiï ïï vitaminom Ie.

Activity of lymphocyte chalone-tissue-specific inhibitor of cell proliferation and its effect on immunocompetent cells in antioxidant insufficiency (AOI) and its correction with vitamin E were studied in the work. It was stated that lymphocyte chalone quantity in AOI increased 2 times as compared with control values and was at the same level when using alpha-tocopherol acetate. The inhibiting activity of chalone was preserved in relation to the proliferative activity of lymphocytes and disappeared in relation to DNA-synthesis with immunocompetent cells. The study of fatty acids spectrum of lymphocyte membrane phospholipids has shown that lymphocyte chalone normalized the content of saturated and unsaturated fatty acids that demonstrates the antioxidant properties of lymphocyte chalone.