[Clinical-laboratory parallels in crush syndrome]. / Kliniko-laboratornye paralleli pri sindrome dlitel'nogo sdavleniia.

Biochemical evaluation of 60 patients with crush syndrome developing after the Armenian earthquake demonstrated informative value of some parameters: total blood protein, aspartate and alanine aminotransferase, myoglobin and middle-mass molecules. An aggravation of the disease accompanied acute renal failure and concomitant injuries. The above parameters proved valuable criteria in diagnosis of the clinical alterations.

[Hyperbaric oxygenation in the treatment of crush syndrome]. / Giperbaricheskaia oksigenatsiia v lechenii krash-sindroma.

Comparison of the results of treatment of 60 patients with the crush syndrome by applying a course of hyperbaric oxygenation (HBO) (the main group) with the results of treatment of 50 analogous patients not subjected to HBO (control group) showed the advantages of barotherapy. The latter contributed to reduction of tissue hypoxia, relative normalization of renal function, particularly in patients with acute renal failure, lessening of toxemia, and rapid reparative processes. This was manifested by alleviation of anemia and myoglobinemia, and diminished level of middle-mass molecules in the blood. In the control group the positive dynamics was less marked. The high efficacy of HBO allows the authors to recommend it as a measure in the complex treatment of the crush syndrome.

[Effect of hyperbaric oxygenation on the bioelectric activity of the heart in long-term crush syndrome]. / Vliianie giperbaricheskoi oksigenatsii na bioélektricheskuiu aktivnost' serdtsa pri sindrome dlitel'nogo sdavleniia.

A study was made of the effect of continuous hyperbaric oxygenation (HBO) on the ECG and the clinical status of 60 patients with crush syndrome. Of these, 15 persons had acute renal failure (ARF). Before the treatment was started, the patients demonstrated tachycardia, myocardial hypoxia, derangement of nutrition and coronary circulation. The ratio of the T to the R wave was increased in the II standard lead, the ECG readings showed hyperkalemia. These pathological alterations were more pronounced in ARF patients. After HBO was completed, the patients manifested positive changes in the clinical status and in the laboratory analyses. Hypoxia and intoxication decreased to a considerable measure, myocardial metabolism returned to normal. In the control group, the positive changes turned out much less marked.