ABSTRACT
AIM: To analyse 24-h rhythm of blood pressure (BP) and its influence on the rate and severity of left ventricular hypertrophy (LVH) in patients with chronic renal failure (CRF) on replacement therapy (peritoneal dialysis - PD). MATERIAL AND METHODS; 70 CRF patients on PD were studied. Their examination included clinical, biochemical tests, automatic 24-hour blood pressure monitoring, transthoracic echocardiography. RESULTS: Non-dipper and night-peaker disorders of BP 24-hour pattern were registered in 81.4% patients irrespective on hypertension severity. Left ventricular myocardial hypertrophy was 87.7% in patients with disturbed 24-h BP rhythm and 53.8% (p = 0.015) in normal BP rhythm. LV myocardial mass index median was 223 and 129 g/cm2 (p = 0.026), respectively. Concentric and excentric models of LV hypertrophy occurred with the same rate in normal and disturbed 24-h rhythm of BP. CONCLUSION: CRF patients on PD are characterized by disorders of 24-h BP rhythm independent of hypertension severity. Night-peaker pattern of BP is a risk factor of development and/or progression of LV hypertrophy.
Subject(s)
Blood Pressure , Kidney Failure, Chronic/physiopathology , Peritoneal Dialysis , Adult , Blood Pressure Monitoring, Ambulatory , Echocardiography , Female , Humans , Hypertension/diagnosis , Hypertension/epidemiology , Hypertension/etiology , Hypertrophy, Left Ventricular/diagnosis , Hypertrophy, Left Ventricular/epidemiology , Hypertrophy, Left Ventricular/etiology , Kidney Failure, Chronic/complications , Kidney Failure, Chronic/therapy , Male , Risk FactorsABSTRACT
Validity of criteria of so called "pulmogenic hypertension" in chronic obstructive pulmonary diseases was assessed with the use of a questionnaire and simultaneous 24 hour monitoring of blood pressure and peak expiratory rate in 80 and 28 patients, respectively. This method of bifunctional monitoring allowed to study relationship between blood pressure level and degree of bronchial obstruction. The results did not confirm the presence of "pulmogenic hypertension" as a special form of arterial hypertension.
Subject(s)
Hypertension, Pulmonary/diagnosis , Hypertension, Pulmonary/physiopathology , Terminology as Topic , Adult , Aged , Diagnosis, Differential , Female , Humans , Hypertension, Pulmonary/etiology , Male , Middle Aged , Pulmonary Disease, Chronic Obstructive/complications , Severity of Illness IndexABSTRACT
AIM: Detection of early atherosclerosis and some mechanisms of dyscirculatory encephalopathy development late after the Chernobyl accident. MATERIAL AND METHODS: 57 men (mean age 45.9 +/- 1.18 years) exposed to ionizing radiation after the Chernobyl accident in 1986-1987 (random sample) and 28 healthy men (control) entered the trial. Their examination included ECG, echocardiography, veloergometry (on demand), 24-h monitoring of arterial pressure and Holter monitoring, B-mode ultrasonic scanning in combination with dopplerography and color mapping of blood flow (triplex scanning) of the right and left common carotid arteries on the unit Vingmed CFM (Diasonic Sonotron, Germany) using 7.5 MHz sensor. Blood serum was examined for total cholesterol and triglycerides. RESULTS: Clinical manifestations of atherosclerosis--ischemic heart disease--were detected in 11 examinees (19.3%). Thickening of the complex intima-media which is thought an early marker of atherosclerosis was identified in 28 examinees (49.1%), stenoses and atherosclerotic plaques--in 17(30%) examinees. Three of them had hemodynamically significant stenoses. Increased blood flow in common carotid arteries combined with enhanced pump function of the left ventricle. CONCLUSION: Atherosclerotic vascular alterations detected in the Chernobyl wreckers were encountered 2 times more frequently than clinical symptoms of atherosclerosis. One of the mechanisms of dyscirculatory encephalopathy in them is high blood volume circulating in common carotid arteries in combination with left ventricular pump hyperfunction.
Subject(s)
Carotid Artery, Common/diagnostic imaging , Carotid Stenosis/diagnostic imaging , Power Plants , Radiation Injuries/diagnostic imaging , Radioactive Hazard Release , Ultrasonography, Interventional , Adult , Carotid Artery, Common/pathology , Carotid Stenosis/complications , Carotid Stenosis/etiology , Carotid Stenosis/pathology , Humans , Male , Middle Aged , Radiation Injuries/complications , Radiation Injuries/etiology , UkraineABSTRACT
20 patients who have undergone difficult operations on locomotor apparatus with autohemotransfusion were examined. Twenty-four-hour ECG-monitoring before and after operation was used for registration of bioelectric myocardial activity. Tachycardia, in night time chiefly, disorders of circadian cardiac rhythm, ischemic depression of ST-segment without clinical symptoms were revealed in all the patients in postoperative period. These disorders are maximal in older age group that must be taken into account during planning surgery and hemotransfusion.
