ABSTRACT
The results of antibiotic prophylaxis in 148 patients with destructive acute surgical sicknesses of abdominal cavity being urgently operated in the Republican hospital of Baku city from 2011 to 2016 were analyzed. Sixty-five patients were in the basic group which had got as preoperative antibiotic prophylaxis 120-hour course of amoxiclav (amoxicillin in combination with clavulanic acid). Eighty-three patients were in the control group who have performed a surgical intervention with pre-operative 120-hour antibiotic prophylaxis by Claforan (cefotaxime) combining with Metrogel (metronidazole). it was showed that applying antibiotic prophylaxis using amoxiclav positively lowered the frequency of as postoperative purulent-septic complications as recurring operations to 8.1%. How to cite this article: Jamalov FH, Agayev RM, Achundov IT, Huseynov SG, Jamalova TP. Antibacterial Prophylaxis in Emergency Surgery of Abdominal Infection. Euroasian J Hepatogastroenterol, 2018;8(2):116-120.
ABSTRACT
BACKGROUND/AIMS: This study aimed to review the authors' surgical experience in hepatic hydatid disease over a 15-year period. METHODOLOGY: The results of surgical treatment of 484 patients (37.2% male; 62.8% female) aged 5-82 years, with liver echinococcosis (LE), were analyzed. RESULTS: Complications of the disease were evident in 226 (47%) patients. These were: cyst calcination, 34 (7%); bile ducts rupture, 128 (26.4%); cyst suppuration, 120 (24.8%); and abdominal cavity perforation, 6 (1.2%). In the diagnostics of liver echinococcosis and its complications, the most informative techniques were ultrasonography and CT. Surgical treatment included: echinococcectomy with complete liquidation of residual cavity (22.1%); echinococcectomy with suturing and external drainage of residual cavity (57.8%); external drainage of residual cavity (11.4%); pericystectomy (6.6%); and liver resection (2.1%). Postoperative complications developed in 118 (24.3%) patients; of these, specific complications occurred in 74 (15.3%) patients. Eight (1.6%) patients had lethal outcomes. The development of purulent biliary complications was connected with peculiarities of parasitic cysts, the character of preoperative complications of the hydatid cysts, and the type of operative intervention: in patients, who underwent echinococcectomy with complete liquidation of residual cavity these complications developed in 4% of cases, whereas the occurrence in patients who underwent operations with external drainage of residual cavity, was 15.2% (P < 0.01). CONCLUSIONS: Laser irradiation is an essential aid in the prevention of specific complications: application during operation for processing a residual cavity and in the postoperative stage (transcutaneous irradiation of a zone of residual cavity projection or direct irradiation through a drainage tube) is effective. The laser processing of a residual cavity accelerates healing of the residual cavity by approximately 1/3 of the time, and reduces the number of purulent complications by almost 2.5, thereby reducing the patient's number of hospital stay days.
