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1.
Rev Sci Tech ; 21(3): 645-61, 2002 Dec.
Article in English | MEDLINE | ID: mdl-12523704

ABSTRACT

The authors evaluate the impact of foot and mouth disease (FMD) and control of the disease in the Philippines using cost-benefit analysis. A scenario in which FMD control is maintained at recent levels with continued presence of the disease is compared to scenarios in which a publicly funded programme achieves eradication by 2005 (current policy objective), 2007 and 2010. Under varying assumptions regarding the development of exports of livestock products following eradication, estimated benefit-cost ratios for the investment in eradication range from 1.6 (2010, no exports) to 12.0 (2005, export of 5,000 tons each of low-value and high-value livestock products annually), indicating eradication to be an economically viable investment. The commercial swine sector is estimated to capture 84% of the benefits generated by the public investment in eradication, versus 4% by backyard swine producers. The implications of these results within the context of regional efforts to control FMD in South-East Asia are explored.


Subject(s)
Foot-and-Mouth Disease/economics , Foot-and-Mouth Disease/prevention & control , Swine Diseases/economics , Swine Diseases/prevention & control , Animals , Cost-Benefit Analysis , Disease Outbreaks/economics , Disease Outbreaks/prevention & control , Disease Outbreaks/veterinary , Foot-and-Mouth Disease/epidemiology , Philippines/epidemiology , Swine , Swine Diseases/epidemiology , Vaccination/economics , Vaccination/veterinary
2.
Science ; 287(5461): 2185-95, 2000 Mar 24.
Article in English | MEDLINE | ID: mdl-10731132

ABSTRACT

The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans. We have determined the nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map. Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation. The genome encodes approximately 13,600 genes, somewhat fewer than the smaller Caenorhabditis elegans genome, but with comparable functional diversity.


Subject(s)
Drosophila melanogaster/genetics , Genome , Sequence Analysis, DNA , Animals , Biological Transport/genetics , Chromatin/genetics , Cloning, Molecular , Computational Biology , Contig Mapping , Cytochrome P-450 Enzyme System/genetics , DNA Repair/genetics , DNA Replication/genetics , Drosophila melanogaster/metabolism , Euchromatin , Gene Library , Genes, Insect , Heterochromatin/genetics , Insect Proteins/chemistry , Insect Proteins/genetics , Insect Proteins/physiology , Nuclear Proteins/genetics , Protein Biosynthesis , Transcription, Genetic
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