ABSTRACT
Drooling is a pathologic condition that is commonly associated with neurodisability and poor quality of life. An elderly dementia patient and an adult cancer patient suffered from persistent drooling, and they were both prescribed glycopyrrolate 0.5-mg sorbitol lollipops, per recommendation of their local compounding pharmacist. The severity and frequency of drooling decreased substantially in both patients, and there were no reported adverse effects. These two case reports demonstrate the safety and efficacy of glycopyrrolate lollipops in managing excessive salivation, as well as the importance of the triad relationship in addressing the individual patient needs.
Subject(s)
Glycopyrrolate , Sialorrhea , Adult , Aged , Humans , Muscarinic Antagonists , Quality of Life , Sialorrhea/drug therapy , Sialorrhea/etiology , SorbitolABSTRACT
The human papillomaviruses are the most common sexually transmitted infections in the U.S., and the majority of these infections are cleared by the body's natural immune system without causing any harm. The high-risk human papillomavirus types, however, cause approximately 5 percent of all cancers worldwide. A prophylactic vaccine was recently introduced, but there is still no commercially available treatment that targets active infections. This case study discusses a 48-year-old female who was diagnosed as human papillomavirus positive (+) following a routine gynecological examination. Upon discussion with a compounding pharmacist, the obstetrician/gynecologist prescribed Green Tea Extract 15% Vaginal Cream and Curcumin 250 mg Vaginal Suppositories, to be applied on alternate days for a period of 3 months. After only 1 month of treatment, the gynecologic cytology report tested negative for human papillomavirus. The patient was very satisfied with the compounded medications prescribed (treatment satisfaction questionnaire) and the human papillomavirus (+) diagnosis was reported to have only little/moderate impact on the patient's sexual life (Human Papillomavirus Impact Profile questionnaire). The successful results obtained in this case study confirm the beneficial properties of green tea extract and curcumin against the viruses, and highlight the key role of pharmaceutical compounding in current therapeutics.
Subject(s)
Curcumin/therapeutic use , Drug Compounding , Enzyme Inhibitors/therapeutic use , Papillomavirus Infections/drug therapy , Phytotherapy , Plant Extracts/therapeutic use , Tea , Administration, Intravaginal , Female , Humans , Middle Aged , Patient Satisfaction , Suppositories , Treatment Outcome , Vaginal Creams, Foams, and JelliesABSTRACT
An adult diabetic male with three toes amputated on his right foot presented with an ulcer infection on his left foot, unresponsive to conventional antifungal oral medication for over two months. The ulcerated foot wound had a large impairment on the patient's quality of life, as determined by the Wound-QoL questionnaire. The compounding pharmacist recommended and the physician prescribed two topical compounded medicines, which were applied twice a day, free of charge at the compounding pharmacy. The foot ulcer infection was completely resolved following 13 days of treatment, with no longer any impairment on the patient's quality of life. This scientific case study highlights the value of pharmaceutical compounding in current therapeutics, the importance of the triad relationship, and the key role of the compounding pharmacist in diabetes care.
