1.
Afr J Med Med Sci
; 30(1-2): 105-9, 2001.
Article
in English
| MEDLINE
| ID: mdl-14510162
ABSTRACT
The effect of administration of aqueous extract of Parquetina nigrescens on haematological parameters was investigated in haemorrhagic anaemic rats from which about 30% of blood volume was removed through ocular vein under chloroform anesthesia. Anaemic rats were administered 400 mg/kg, 800 mg/kg and 1600 mg/kg of P. nigrescens aqueous extract daily for four weeks. Significant (P < 0.05) progressive and dose related increases were observed in red blood cell count (RBC, 10(6)/ml), Haemoglobin (gm/dl), Haematocrit (Hct, %) and Reticulocyte (%) while a decrease in white blood cell count (WBC 10(3) microl) was observed in test rats treated with aqueous extract of P. nigrescens when compared with both normal and bled control rats.