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1.
Indian J Ophthalmol ; 69(3): 598-602, 2021 03.
Article in English | MEDLINE | ID: mdl-33595483

ABSTRACT

Purpose: The aim of this study ws to evaluate prognostic factors associated with final visual outcome in patients with congenital cataract associated with congenital rubella syndrome. Methods: A prospective interventional analysis of preoperative systemic and ocular features of 56 eyes of 28 seropositive infants of less than 12 months presenting to us with bilateral cataract was performed. All infants were surgically treated with cataract extraction, posterior capsulorhexis, and anterior vitrectomy followed by visual rehabilitation. Intraocular lens implantation was done in children after 2 years of age. Outcome data were collected till children reached the fifth chronological age. Chi-square test was used as a test of significance for qualitative data. Results: Of the 56 eyes, 44.6% eyes had vision better than 20/60. Important preoperative factors related to poor visual prognosis were morphology of cataract (P = 0.004), microphthalmos (P < 0.001), features suggestive of iris hypoplasia (P < 0.001), optic atrophy (P < 0.001), nystagmus (P = 0.02), and associated neurological anomalies (P = 0.0023). We found no significant statistical association between postoperative visual outcome and isolated rubella retinopathy, cloudy cornea, cardiological, and ontological abnormalities. Conclusion: Cataract associated with rubella is a common cause of congenital cataract in developing countries. Determining prognostic factors helps us in parent counseling and planning treatment protocols. Nevertheless, early detection and treatment with adequate multidisciplinary approach remains priority for improving long-term visual outcomes.


Subject(s)
Cataract Extraction , Cataract , Rubella Syndrome, Congenital , Rubella , Cataract/complications , Cataract/diagnosis , Cataract/epidemiology , Child , Follow-Up Studies , Humans , Infant , Lens Implantation, Intraocular , Prognosis , Prospective Studies , Retrospective Studies , Rubella Syndrome, Congenital/complications , Rubella Syndrome, Congenital/diagnosis , Rubella Syndrome, Congenital/epidemiology , Treatment Outcome , Visual Acuity
2.
Indian J Ophthalmol ; 66(1): 166-167, 2018 01.
Article in English | MEDLINE | ID: mdl-29283153

ABSTRACT

Here, we report a rare case of bilateral medial rectus palsy following closed head injury. An adult male had an accidental fall which rendered him unconscious. This was followed by diplopia and restricted ocular motility. He received supportive medical therapy. He was examined for systemic medical and ophthalmic findings. Routine laboratory tests and imaging techniques were employed as per the symptoms. Diffusion-weighted imaging on magnetic resonance imaging proved it to be a rare presentation of small bilateral midbrain infarct. He recovered fully after 8 months.


Subject(s)
Brain Infarction/complications , Diplopia/etiology , Head Injuries, Closed/complications , Mesencephalon/blood supply , Oculomotor Muscles/physiopathology , Oculomotor Nerve Diseases/complications , Adult , Brain Infarction/diagnosis , Diplopia/diagnosis , Diplopia/physiopathology , Eye Movements , Follow-Up Studies , Head Injuries, Closed/diagnosis , Humans , Magnetic Resonance Imaging , Male , Oculomotor Nerve Diseases/diagnosis , Oculomotor Nerve Diseases/physiopathology
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