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Can J Neurol Sci ; 36(2): 222-6, 2009 Mar.
Article in English | MEDLINE | ID: mdl-19378719

ABSTRACT

BACKGROUND: Cervical dystonia (CD) may be classified according to the underlying cause into primary or secondary CD. Previous exposure to neuroleptics is one of the main causes of adult-onset secondary dystonia. There are few reports that characterize the clinical features of primary CD and secondary neuroleptic-induced CD. Herein our aim was to investigate a series of patients with neuroleptic induced tardive CD and to describe their clinical and demographic features. PATIENTS AND METHODS: We retrospectively evaluated 20 patients with neuroleptic-induced tardive CD and compared clinical, demographic and therapeutic characteristics to another 77 patients with primary CD. All patients underwent Botulinum toxin type-A therapy. RESULTS: We did not identify any relevant clinical and demographic characteristics in our group of patients that could be used to distinguish tardive and primary CD. CONCLUSION: Patients with tardive CD presented demographic characteristics and disease course similar to those with primary CD.


Subject(s)
Antipsychotic Agents/adverse effects , Dyskinesia, Drug-Induced/etiology , Torticollis/etiology , Adolescent , Adult , Aged , Botulinum Toxins, Type A/therapeutic use , Demography , Dyskinesia, Drug-Induced/classification , Dyskinesia, Drug-Induced/drug therapy , Female , Humans , Male , Middle Aged , Neck , Neuromuscular Agents/therapeutic use , Retrospective Studies , Torticollis/classification , Torticollis/drug therapy
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