[Treatment of premenstrual tension syndrome (PMS) with lisuride maleate]. / Tratamiento del síndrome de tensión premenstrual (STP) con maleato de lisurida.

The etiology of PMS has not yet been defined, although there are several theories among which it is reported that there is an increase in prolactine levels involved in it. The purpose of this study was to evaluate a dopamine receptor agonist (lisuride maleate), in the treatment of PMS. 35 patients between 19 and 35 years old were recruited in a prospective study design, with diagnosis of PMS and no other gynecological disorder ruled out clinical and ultrasonographic examination, women with no previous treatment and with no use of hormonal agents, these patients were treated for three months with lisuride maleate, 0.3 mg-day in a three dosage scheme per day, the following symptoms were evaluated: headaches, mastalgia, bloating, edema of lower extremities and myalgia in legs, as well as hormonal parameters before and after treatment with estrogens, progesterone, prolactine, luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone, which were prescribed in the luteal phase (day 21). Results obtained were: reduction of all symptoms scores versus pretreatment: Headache from 85.7 to 20%, mastalgia from 91.4 to 25%, bloating from 74.2 to 40%, edema in lower extremities from 85.7 to 30%, myalgia in legs, from 61 to 34%. The hormonal profile only showed changes in FSH, since the basal pretreatment level was found in 18.6 and the post-treatment value was 13.86, progesterone from 2.7 to 4.6 and prolactine from 7.74 to 6.82. We conclude the lisuride maleate is a good option to the PMS treatment, since a significative reduction of symptoms are induced and it is well tolerated.

[Considerations on 200 cases of vaginal burns by potassium permanganate]. / Consideraciones sobre 200 casos de quemaduras vaginales con permanganato de potasio.

PIP: Potassium permanganate in tablets is still used in Mexico under the wrong belief that it will induce abortion. What it does, instead, is to provoke deep burns and ulcers in the vaginal walls, and to cause serious hemorrhage. This study investigates 200 women who used potassium permanganate as an abortifacient agent, and who needed hospitalization. Average age was 28; 58.5% had 4 or more children; 88.5% were married, and 11.5% were not; all patients belonged to the lowest socioeconomic class. Many had antecedents of induced abortion, and most had been amenorrheic for only 4-5 weeks. 23.5% of patients was not pregnant. Acute anemia was the most common complication, followed by hypovolemic shock. In this series there was 21.5% of diagnostic error, which shows the importance of suspecting this pathologic entity in women bleeding profusely and for whom induced abortion is suspected.^ieng