ABSTRACT
OBJECTIVE: To identify the association between exposition to talcum powder and talcosilicosis in a cosmetic factory. METHODS: A descriptive and prospective survey including 24 workers from the bottling and grinding areas was performed. All patients had chest roentgenography. They were separated into two groups: the first patients exposed up to a period of five years and the second with more than five years exposure. Environmental monitoring of high flow polyvinyl chloride filters and galvimetric analysis was performed. The dust analysis was performed in 12 inhaling powders, eight environmental and four in workers. A Fisher exact test was applied. RESULTS: All of the exposed workers displayed radiographic findings compatible with talcosis; 18 (75%) patients had light talcosis and 6 (25%) moderate. The Fisher test was 13.7 with a p value of 0.004. Dust analysis showed: five were reported over the maximum allowed levels corresponding to the areas of compact cosmetics grinders, powder grinders, powder dispensers and the talcum final line. The analyzed talcum powder contained more than 95% of free silica. CONCLUSIONS: The association was confirmed between the exposure and the presence of talcosis.
Subject(s)
Pneumoconiosis/epidemiology , Talc , Adult , Female , Humans , Male , Middle Aged , Pneumoconiosis/etiology , Prospective Studies , Young AdultABSTRACT
OBJECTIVE: To identify the association between industrial bronchitis and exposure to hydroalcohol. METHODS: In a prospective study, 80 workers exposed to hydroalcohol answered a standardized questionnaire and had two spirometry tests based on the American Thorax Society (ATS) criteria, to evaluate functional capacity and predominant spirometric patterns. The test included the parameters: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), the ratio FEV1/FVC, the peak expiratory flow (PEF), the forced expiratory flow 25-50 (FEF50) and the forced expiratory flow 25-75% (FEF 25%-75%). Fisher exact test was used to identify differences. An environmental sampling of hydroalcohols was done as well. RESULTS: 85 % Of workers were women and 15 % men, with respiratory symptoms as follows: 25 % with cough and expectoration, 14 % thoracic pressure feeling, 23 % dyspnea; 36 % eye, nose or throat irritation. The spirometry results were: 25 % for pulmonary normal pattern; 66 % had obstructive pattern; 3 % had restrictive patterns and 6 % mixed pattern. 25 % of workers with obstructive pattern and 10 % of normal pattern had symptoms. It was obtained an OR = 1.9 (95 % CI = 1.135-3.195; p = 0.021) for the time of exposure to hydroalcohols and the presence of industrial bronchitis. The monitoring of hydroalcohols reported: 131.1 mg/m3 for isopropyl alcohol and 438.3 mg/m3; 49 workers (61 %) had bronchitis symptoms and 58 (72 %) showed obstructive or mixed patterns in the spirometry tests. The exposure to hydroalcohols was below the limits established by the Mexican Official Norm.