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8.
Clin Exp Dermatol ; 14(5): 341-6, 1989 Sep.
Article in English | MEDLINE | ID: mdl-2532985

ABSTRACT

Neutrophilic eccrine hidradenitis is a new neutrophilic dermatosis recently reported in association with acute myelogenous leukaemia and other malignancies, usually occurring during chemotherapy. The authors report two new cases, one of which was a patient with chronic lymphocytic leukaemia who had been treated with chlorambucil for 2 years. The clinical and histopathological features of the published cases are reviewed and the possible pathogenesis of this new syndrome is discussed.


Subject(s)
Drug Eruptions/etiology , Eccrine Glands/pathology , Leukemia, Myeloid, Acute/drug therapy , Sweat Glands/pathology , Aged , Eccrine Glands/drug effects , Female , Humans , Inflammation , Leukemia, Myeloid, Acute/pathology , Male , Middle Aged , Neutrophils/pathology , Sweat Glands/drug effects
9.
Dermatologica ; 179(4): 200-1, 1989.
Article in English | MEDLINE | ID: mdl-2515979

ABSTRACT

Since an increased incidence of occlusive vascular disease has been reported in psoriasis, serum levels of apolipoproteins AI, AII and B were determined in 61 patients with the disease and compared with that of 34 healthy controls. No significant differences were found between the two groups. These findings suggest that the occurrence of thromboembolic disorders in psoriasis is not related to altered levels of apolipoproteins AI, AII, B in these patients.


Subject(s)
Apolipoproteins A/blood , Apolipoproteins B/blood , Lipoproteins, HDL/blood , Psoriasis/blood , Adolescent , Adult , Aged , Apolipoprotein A-I , Apolipoprotein A-II , Female , Humans , Male , Middle Aged
11.
Dermatologica ; 178(3): 164-6, 1989.
Article in English | MEDLINE | ID: mdl-2721807

ABSTRACT

Clear-cell syringoma is a histologic variant of syringoma that is otherwise clinically indistinguishable from ordinary syringoma. This variant is formed by cells that have pale or clear cytoplasm as a result of glycogen accumulation. There is a high association of clear-cell syringoma and diabetes mellitus. A case of clear-cell syringoma associated with diabetes mellitus is described. Electron microscopic examination revealed that periluminal cells showed intra- and extracytoplasmic multivesicular bodies that may be characteristic of the clear-cell variant. Immunohistochemistry for carcinoembryonic antigen (CEA) showed ordinary syringomas as in the presence of CEA within and surrounding duct-like spaces.


Subject(s)
Adenoma/ultrastructure , Eyelid Neoplasms/ultrastructure , Sweat Gland Neoplasms/ultrastructure , Adenoma/analysis , Aged , Carcinoembryonic Antigen/analysis , Cytoplasm/ultrastructure , Cytoplasmic Granules/ultrastructure , Epithelium/ultrastructure , Eyelid Neoplasms/analysis , Female , Humans , Immunohistochemistry , Microscopy, Electron , Sweat Gland Neoplasms/analysis
13.
J Cutan Pathol ; 15(1): 40-2, 1988 Feb.
Article in English | MEDLINE | ID: mdl-3351062

ABSTRACT

Eruptive vellus hair cyst and steatocystoma multiplex are infrequent lesions. Although there are clinical similarities between both entities, histologic features are distinctive. Especially noteworthy is the presence of sebaceous glands within the cyst wall of steatocystoma. We describe herein a patient with a familial monomorphous papular eruption on the forehead, biopsies from which showed features of both eruptive vellus hair cyst and steatocystoma multiplex.


Subject(s)
Cysts/pathology , Epidermal Cyst/pathology , Hair , Skin Diseases/pathology , Adult , Biopsy , Female , Humans , Skin Diseases/genetics
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