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1.
J Laryngol Otol ; 132(1): 14-21, 2018 Jan.
Article in English | MEDLINE | ID: mdl-29173195

ABSTRACT

BACKGROUND: Tracheoesophageal puncture represents the 'gold standard' for voice restoration following laryngectomy. Tracheoesophageal puncture can be undertaken primarily during laryngectomy or in a separate secondary procedure. There is no current consensus on which approach is superior. The current evidence comparing primary and secondary tracheoesophageal puncture was assessed. METHODS: A systematic review and meta-analysis of articles comparing outcomes for primary and secondary tracheoesophageal puncture after laryngectomy were conducted. Outcome measures were: voice success, overall complication rate and pharyngocutaneous fistula rate. RESULTS: Eleven case series met the inclusion criteria, two prospective and nine retrospective. Meta-analysis did not demonstrate statistically significant differences in overall complication rate or voice outcomes, though it suggested a significantly increased risk of pharyngocutaneous fistula in primary compared to secondary tracheoesophageal puncture. CONCLUSION: Primary tracheoesophageal puncture is a safe and efficient approach for voice rehabilitation. However, secondary tracheoesophageal puncture should be preferred where there is a higher risk of pharyngocutaneous fistula.


Subject(s)
Esophagus/surgery , Laryngectomy/adverse effects , Postoperative Complications , Speech, Alaryngeal/methods , Trachea/surgery , Voice Disorders , Voice/physiology , Humans , Laryngeal Neoplasms/surgery , Larynx, Artificial , Punctures/methods , Voice Disorders/etiology , Voice Disorders/physiopathology , Voice Disorders/surgery
2.
J Laryngol Otol ; 130(6): 571-4, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27112730

ABSTRACT

BACKGROUND: Head and neck cancer emergency presentations are uncommon but persistent. However, there is little published literature on this aspect of cancer and patient demographics. This study aimed to assess the incidence, patient profile, tumour site and stage of emergency cancer presentations in our region. METHOD: Retrospective review of regional cancer database over a five-year period. RESULTS: Emergency presentations accounted for 7 per cent of all cases. There was no difference in patient age and risk factors between the emergency and non-emergency presentations. The emergency presentation group showed a greater proportion of female patients compared to the non-emergency presentation group (30 vs 15 per cent). In all emergency presentations, the cancer was at advanced stages. Oropharyngeal cancer was the commonest emergency presentation of cancer, but the third commonest in the non-emergency group. CONCLUSION: Emergency presentations are increasing annually. Female patients and oropharyngeal cancer showed greater representation compared to male patients and laryngeal cancer.


Subject(s)
Carcinoma, Small Cell/epidemiology , Carcinoma, Squamous Cell/epidemiology , Emergencies/epidemiology , Head and Neck Neoplasms/epidemiology , Melanoma/epidemiology , Rhabdomyosarcoma/epidemiology , Carcinoma, Small Cell/complications , Carcinoma, Small Cell/diagnosis , Carcinoma, Small Cell/pathology , Carcinoma, Squamous Cell/complications , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/pathology , Databases, Factual , Deglutition Disorders/epidemiology , Deglutition Disorders/etiology , Emergency Service, Hospital , Female , Head and Neck Neoplasms/complications , Head and Neck Neoplasms/diagnosis , Head and Neck Neoplasms/pathology , Humans , Laryngeal Neoplasms/complications , Laryngeal Neoplasms/diagnosis , Laryngeal Neoplasms/epidemiology , Male , Melanoma/complications , Melanoma/diagnosis , Melanoma/pathology , Mouth Neoplasms/complications , Mouth Neoplasms/diagnosis , Mouth Neoplasms/epidemiology , Neoplasm Staging , Oropharyngeal Neoplasms/complications , Oropharyngeal Neoplasms/diagnosis , Oropharyngeal Neoplasms/epidemiology , Pharyngitis/epidemiology , Pharyngitis/etiology , Prognosis , Referral and Consultation , Respiratory Sounds/etiology , Retrospective Studies , Rhabdomyosarcoma/complications , Rhabdomyosarcoma/diagnosis , Rhabdomyosarcoma/pathology , Sex Distribution , Squamous Cell Carcinoma of Head and Neck , Survival Rate , United Kingdom/epidemiology
3.
J Laryngol Otol ; 129(8): 807-11, 2015 Aug.
Article in English | MEDLINE | ID: mdl-26044458

ABSTRACT

BACKGROUND: Haemoptysis is an uncommon presenting symptom to the ENT clinic and ward, but has potentially sinister aetiology. This article aims to provide a systematic and evidence-based method of managing patients with haemoptysis. METHODS: The data in this article are based on a literature search performed using PubMed in August 2013. The keywords used included 'haemoptysis' in combination with 'otolaryngology', 'ENT', 'head & neck', 'diagnosis', 'management', 'investigations' and 'treatment'. RESULTS: The majority of published literature on the subject is level IV evidence. However, this can guide ENT specialists in assessing, investigating and managing presentations of haemoptysis. CONCLUSION: Understanding the different causes of haemoptysis is important for the otolaryngologist. The main concern is the detection of a malignant lesion in the upper aerodigestive tract or tracheobronchial tree. A thorough history and systematic examination can aid diagnosis.


Subject(s)
Evidence-Based Medicine/methods , Hemoptysis/etiology , Hemoptysis/therapy , Otolaryngology , Humans , Otorhinolaryngologic Neoplasms/complications , Otorhinolaryngologic Neoplasms/diagnosis , Otorhinolaryngologic Neoplasms/therapy
4.
J Laryngol Otol ; 129(5): 416-20, 2015 May.
Article in English | MEDLINE | ID: mdl-25994381

ABSTRACT

OBJECTIVE: To review the literature on enhanced recovery programmes in head and neck surgery. METHOD: A systematic review was performed in May 2013. RESULTS: Thirteen articles discussing enhanced recovery after laryngectomy, neck dissection, major ablative surgery and microvascular reconstruction were identified. Articles on general pre-operative preparation and post-operative care were also reviewed. CONCLUSION: Considerable evidence is available supporting enhanced recovery in head and neck surgery that could be of benefit to patients and which surgeons should be aware of.


Subject(s)
Otorhinolaryngologic Surgical Procedures/rehabilitation , Postoperative Care/methods , Head and Neck Neoplasms/surgery , Humans
5.
J Laryngol Otol ; 128(3): 302-6, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24548675

ABSTRACT

INTRODUCTION: Complementary and alternative medicine usage, though rising, remains largely devoid of a sound scientific basis; however, there is increasing evidence to support its use in cancer therapy. AIM: To present the case of a patient with laryngeal carcinoma who made a full recovery following mistletoe therapy, despite failing to respond to chemoradiotherapy and salvage laryngectomy. DESIGN: Case report with relevant literature review. RESULTS: The patient developed extensive, unresectable stomal recurrence, and it was deemed appropriate to supply palliative care only. Following treatment with mistletoe extract injections after palliative radiotherapy, he recovered fully and was eventually discharged from care. CONCLUSION: The benefit of mistletoe in laryngeal cancer treatment requires further investigation, and might be considered in selected patients, as an adjunct or when other conventional therapies have failed.


Subject(s)
Antineoplastic Agents, Phytogenic/therapeutic use , Carcinoma, Squamous Cell/drug therapy , Laryngeal Neoplasms/drug therapy , Mistletoe , Phytotherapy , Plant Extracts/therapeutic use , Aged , Carcinoma, Squamous Cell/pathology , Humans , Injections , Laryngeal Neoplasms/pathology , Male , Salvage Therapy , Treatment Outcome
6.
Eur Arch Otorhinolaryngol ; 271(3): 575-82, 2014 Mar.
Article in English | MEDLINE | ID: mdl-23661062

ABSTRACT

The aim of this study is to describe minimally invasive trans-oral approach for resection of parapharyngeal space (PPS) tumours and to demonstrate surgical technique, resection, repair and outcomes. Five cases were prospectively included in the study. The data collected include age, sex, site, size, pathology, radiological investigations, surgical excision, complications and outcomes. Three females and two male patients underwent trans-oral resection of PPS tumours sized 4-8 cm. The pathology included two deep lobe parotid tumours, one schwannoma, one hibernoma and one primary adenocarcinoma arising form the minor salivary gland. All tumours were resected completely without any technical difficulty. The healing was quick and by primary intention. Patients resumed oral feeding on recovery from general anaesthesia and did not require any significant analgesia beyond the first 2 days. Patient with adenocarcinoma received postoperative radiotherapy and remained disease-free during 4 years post-treatment. No recurrences were observed in patients with benign tumours. No neurovascular injury occurred during surgery and no secondary bleeding was observed. We have demonstrated successful and safe execution of trans-oral resection of large PPS tumours. There were no intra and post-operative complications and there has been no recurrence during the follow-up period. In our experience, it appears to be efficient, safe and minimally invasive compared to the established techniques.


Subject(s)
Adenocarcinoma/surgery , Adenoma, Pleomorphic/surgery , Lipoma/surgery , Minimally Invasive Surgical Procedures/methods , Neurilemmoma/surgery , Parotid Neoplasms/surgery , Pharynx/surgery , Adenocarcinoma/diagnostic imaging , Adenoma, Pleomorphic/diagnostic imaging , Aged , Cohort Studies , Female , Humans , Lipoma/diagnostic imaging , Male , Middle Aged , Neurilemmoma/diagnostic imaging , Parotid Neoplasms/diagnostic imaging , Prospective Studies , Salivary Gland Neoplasms/diagnostic imaging , Salivary Gland Neoplasms/surgery , Tomography, X-Ray Computed
7.
BMJ Case Rep ; 20132013 Nov 18.
Article in English | MEDLINE | ID: mdl-24248322

ABSTRACT

A 57-year-old Caucasian man, otherwise fit and well, presented with a 2-week history of dysphagia, odynophagia. Two weeks prior to the presentation, he had felt a fishbone stuck in his throat which was self-extruded after 3 days. Subsequently he developed a right anterior neck swelling and hoarseness. Transnasal endoscopic examination of larynx revealed an injected and oedematous right hemilarynx with right vocal cord paresis. An ultrasound examination of the neck confirmed a collection in the neck on the right side, and frank pus was aspirated from the neck abscess and he responded well to conservative management. Subsequent examination in follow-up had shown complete recovery of vocal cord movement. The patient did not seek medical attention immediately after getting a 5 cm fishbone extruded from the throat which resulted in significant morbidity. All patients should be alerted to the possibility of delayed complications and they should be encouraged to seek urgent medical attention.


Subject(s)
Abscess/etiology , Foreign Bodies/complications , Larynx/pathology , Streptococcal Infections/diagnosis , Vocal Cord Paralysis/etiology , Deglutition Disorders/etiology , Foreign Bodies/diagnosis , Humans , Male , Middle Aged , Neck/pathology
8.
Scott Med J ; 58(1): 22-5, 2013 Feb.
Article in English | MEDLINE | ID: mdl-23596024

ABSTRACT

BACKGROUND: Variation in otolaryngology intervention rates is reported in the Scottish Surgical Profiles Project. Tonsillectomy is one of the selected key indicator procedures. The variation in practice was discussed nationally at the Scottish Otolaryngology Society summer meetings in 2009 and 2010. NHS Grampian had a significantly higher tonsillectomy rate compared with other Scottish NHS boards. AIMS: To determine the accuracy of NHS Grampian data reported by the Information Service Division (ISD) and to record the appropriateness of listing of patients for tonsillectomy with reference to the Scottish Intercollegiate Guidelines Network (SIGN). METHODS: Retrospective review of case notes and surgical records of patients who had undergone tonsillectomy between March 2007 and March 2008 in NHS Grampian. RESULTS: Between March 2007 and March 2008, 509 tonsillectomy cases were performed in NHS Grampian. This corresponded to the data received from ISD. 87% of tonsillectomies performed were compliant with SIGN guidelines. CONCLUSION: The Scottish otolaryngology clinicians have found the reporting of the intervention rates stimulating and challenging. Discussion of the surgical profile project regularly at national specialty meetings resulted in a preliminary detailed targeted audit of those who were persistent outliers for tonsillectomy. This refuted the presumed reasons for this variation, namely inaccurate figures from ISD and inappropriate listings by clinicians.


Subject(s)
Otolaryngology/statistics & numerical data , Adolescent , Adult , Female , Humans , Male , Retrospective Studies , Scotland , Tonsillectomy/statistics & numerical data , Tonsillitis/surgery
9.
Eur Arch Otorhinolaryngol ; 270(12): 3063-7, 2013 Nov.
Article in English | MEDLINE | ID: mdl-23455577

ABSTRACT

Otolaryngology trainees are expected to be able to successfully perform septoplasty early in their career. An important parameter to assess the success of an operation is to look at the revision surgery rate. This study aimed to investigate the revision nasal surgery rate after septoplasty based on the grade of the primary surgeon. Retrospective review of hospital records of all patients who underwent septoplasty with or without inferior turbinate reduction over 12 years (1998-2010) in a tertiary referral centre in North-East Scotland. Patients were identified from theatre log books and were excluded if they underwent any other simultaneous nasal procedure. Data were collected on demographics, type of primary and revision surgery, grade of surgeon and duration of hospital stay. 2,168 eligible patients (70 % male, 30 % female) with a mean age of 39 years were investigated. Surgeons were divided into four categories: junior trainee (Group A), senior trainee (Group B), staff grade (Group C) and consultant (Group D). There were 753, 644, 298 and 473 patients in Groups A, B, C and D, respectively. The revision rate in Group A was 4.4 % compared to 3.2 % for Group D and this difference was not statistically significant. For their operation, patients in Group A stayed for 1.54 nights compared to 1.47 nights in Group D, the difference being insignificant. Grade of the surgeon does not appear to strongly affect the need for revision nasal surgery and our patients do not appear to be disadvantaged if operated on by trainees.


Subject(s)
Clinical Competence , Nasal Septum/surgery , Otolaryngology/standards , Rhinoplasty/standards , Turbinates/surgery , Adult , Female , Humans , Male , Reoperation , Retrospective Studies , Scotland , Treatment Outcome
12.
J Laryngol Otol ; 126(12): 1296-8, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23098087

ABSTRACT

OBJECTIVES: To present the case of a 'lost' nasogastric tube and to highlight the importance of imaging and/or chest X-ray after nasogastric tube insertion, especially in unreliable patients. CASE REPORT: A 50-year-old man, undergoing radiotherapy treatment for squamous cell carcinoma of the tongue base, was admitted for pain control and nasogastric tube feeding. This patient required multiple nasogastric tubes over a two-week period. The patient repeatedly denied pulling the nasogastric tube out and we were unable to establish the exact mode of nasogastric tube removal. On one such occasion another tube was inserted and a check X-ray showed two feeding tubes; the latest one was lying in the left main bronchus and the old nasogastric tube was observed in the oesophagus, with its upper end jutting above the hypopharynx. It was apparent that the patient had somehow cut the tube and swallowed it. CONCLUSION: This case not only illustrates the importance of flexible nasendoscopy and/or chest X-ray for checking the position of the nasogastric tube, but also highlights that some patients are not tolerant of nasogastric tubes. The use of nasogastric tubes should be avoided in these patients to prevent any self-inflicted injury.


Subject(s)
Bronchi , Enteral Nutrition/instrumentation , Esophagus , Foreign Bodies/diagnostic imaging , Intubation, Gastrointestinal , Carcinoma, Squamous Cell/radiotherapy , Humans , Male , Medical Errors , Middle Aged , Radiography , Tongue Neoplasms/radiotherapy
13.
Eur Arch Otorhinolaryngol ; 267(10): 1641-4, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20379732

ABSTRACT

Objective of the study is to investigate the role of clotting screen in adult patients presenting with epistaxis. The study is a prospective case series done in a teaching hospital in the Northeast of Scotland. Prospective data was collected for 100 consecutive patients with epistaxis admitted to the Department of Otolaryngology over 1 year (2006-2007 August). The demographics, co-morbidities, long-term medications and blood test results were noted for these patients. A retrospective audit of all patients attending the Emergency Department (ED) with epistaxis during the same study period was also performed. The following were measured: frequency of clotting screen performed in patients with epistaxis; the treatment modifying effect of clotting screen results. Of the 100 admitted patients, 45 were male and 55 were female. The majority of them had more than two co-morbidities such as hypertension, ischaemic heart disease and atrial fibrillation. Forty-seven patients were on aspirin, 19 on warfarin and 12 patients on clopidogrel. A clotting screen was done for 80 patients but only 2 patients (2.5%) had an abnormal INR. A total of 356 patients presented to the ED with epistaxis. Of 356 patients, 138 (39%) had their clotting screen checked. Of 138 patients, 42 (30%) were on warfarin. Only 7 patients (7/138 = 5%) had an abnormal result. Our data suggests that routine clotting screen check does not alter the epistaxis management in patients with no risk factors or with stable warfarin dosage. Therefore, routine clotting screen in patients with epistaxis without relevant risk factors is not an evidence-based practice.


Subject(s)
Diagnostic Tests, Routine , Epistaxis/blood , Epistaxis/therapy , Mass Screening , Adult , Anticoagulants/therapeutic use , Cohort Studies , Emergency Service, Hospital , Epistaxis/etiology , Female , Humans , International Normalized Ratio , Male , Retrospective Studies
14.
J Laryngol Otol ; 122(11): 1245-8, 2008 Nov.
Article in English | MEDLINE | ID: mdl-18680636

ABSTRACT

BACKGROUND AND AIMS: Total laryngectomy is a recognised treatment for advanced laryngeal carcinoma. Traditionally, pharyngeal repair is performed with layered sutures. We describe our experience with a technique of closed pharyngoplasty using a linear stapler device. MATERIAL AND METHODS: Ten total laryngectomies were performed from July 2002 to July 2004, using an Ethicon TLC 75 linear stapler for pharyngeal closure. Data collected included age, sex, staging, endoscopic assessment, surgical margins and post-operative course (including complications and swallowing). RESULTS: Patients comprised eight men and two women. The mean age was 55.4 years. Six patients had stage T4 endolaryngeal carcinoma and four had stage T3. Four patients underwent pre-operative radiotherapy. Clear surgical margins were achieved in all patients. One patient developed a pharyngocutaneous fistula. Patients resumed oral intake at 48 hours, or at 72 hours if they had undergone pre-operative radiotherapy. Patients' mean hospital stay was seven days. CONCLUSION: This stapled closed technique for pharyngoplasty is efficient and eliminates the risk of wound contamination, thus theoretically reducing the risk of tumour seeding. In addition, we were able to commence patients on oral fluids at a mean of 48 hours after surgery. The mean hospital stay was seven days. We recommend this technique as an alternative for repairing the pharynx in patients undergoing total laryngectomy for endolaryngeal carcinoma.


Subject(s)
Laryngeal Neoplasms/surgery , Laryngectomy/methods , Pharyngeal Neoplasms/surgery , Surgical Staplers/standards , Surgical Stapling/methods , Aged , Female , Humans , Laryngectomy/standards , Male , Middle Aged , Postoperative Care , Surgical Stapling/standards
15.
J Laryngol Otol ; 122(12): 1360-4, 2008 Dec.
Article in English | MEDLINE | ID: mdl-18331656

ABSTRACT

INTRODUCTION: Within the United Kingdom, there are 50,000 practitioners of complementary and alternative medicine, with five million people consulting these practitioners yearly. The aim of this study was to explore the use of such therapies by patients attending a head and neck oncology clinic in Aberdeen. METHOD: Questionnaires were distributed to 200 patients over an eight-week period. The questionnaire consisted of questions regarding: demographic factors; 48 listed herbal preparations and alternative therapies; reasons for their use; and opinions on their efficacy. RESULTS: One hundred and thirty-eight patients completed the questionnaires. Fifty per cent (69/138) of respondents had used complementary and alternative medicine previously, with 26 per cent having used it in the preceding year. Fifty-five per cent of respondents learned about complementary and alternative medicine use from friends, and the majority obtained such medicines by purchasing from a shop. Fifty per cent (34/69) of respondents stated that their family physician was unaware of their use of complementary and alternative medicine. CONCLUSION: All medical practitioners should be aware of increasing complementary and alternative medicine usage by the United Kingdom population, and should be able to counsel patients appropriately.


Subject(s)
Complementary Therapies/statistics & numerical data , Head and Neck Neoplasms/therapy , Herb-Drug Interactions , Phytotherapy/statistics & numerical data , Plant Preparations , Adult , Antineoplastic Agents/administration & dosage , Attitude to Health , Female , Head and Neck Neoplasms/drug therapy , Head and Neck Neoplasms/epidemiology , Humans , Male , Middle Aged , Patient Acceptance of Health Care/statistics & numerical data , Plant Preparations/administration & dosage , Scotland/epidemiology , Surveys and Questionnaires , Young Adult
16.
Int J Pediatr Otorhinolaryngol ; 71(11): 1725-30, 2007 Nov.
Article in English | MEDLINE | ID: mdl-17714796

ABSTRACT

OBJECTIVE: Little data is available on complementary and alternative medicine (CAM) use in children attending otolaryngology services. We investigated the prevalence and pattern of CAM use among children attending the pediatric otolaryngology department in a tertiary pediatric teaching hospital in Scotland. DESIGN: A cross-sectional survey conducted by administering an anonymous questionnaire to the parents accompanying patients attending the pediatric otolaryngology department. Elective admissions and clinic attendees were included over a 3-month period in 2005/2006. SETTING: Academic tertiary care referral centre in North-East Scotland. PATIENTS: Five hundred and fifty-four consecutive patients aged less than 16 years were eligible. The response rate was 59% (n=327). MAIN OUTCOME MEASURES: Prevalence of CAM use in children. Secondary measures include types of CAM used, indications for use and communication with family physicians. RESULTS: Based on 327 responses, 93 patients (29%) had ever used CAM, 20% within the last year. Commonly used CAM preparations were cod-liver oil, echinacea, aloe vera, cranberry, primrose oil and herbal vitamin supplements. The popular non-herbal CAM included homeopathy, massage, aromatherapy, chiropractic, yoga and reiki. Nineteen percent used CAM for their admission illness. Sixty-one percent of parents thought that CAM was effective and 65% would recommend it to others. Fifty-one percent of parents stated that the family physician was unaware of CAM use by the child. CONCLUSIONS: Despite concerns regarding the efficacy, safety and cost effectiveness of complementary and alternative medicine, its use among the pediatric otolaryngology population is more common than many providers may realize. This has implications for all healthcare workers involved in their care.


Subject(s)
Complementary Therapies/statistics & numerical data , Health Services/statistics & numerical data , Otolaryngology/statistics & numerical data , Otorhinolaryngologic Diseases/therapy , Pediatrics , Adolescent , Child , Child, Preschool , Cross-Sectional Studies , Female , Hospitals , Humans , Male , Prevalence , Surveys and Questionnaires , United Kingdom/epidemiology
18.
Clin Otolaryngol ; 32(1): 24-7, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17298306

ABSTRACT

OBJECTIVES: Traditionally secondary post-tonsillectomy haemorrhage has been thought to be due to post-operative infection and as such is treated with broad-spectrum antibiotics. The aim of this study was to identify clinical evidence of infection in patients with secondary post-tonsillectomy haemorrhage that might justify the use of antibiotics in these patients. DESIGN: Prospective data collection. SETTING: Tertiary University Teaching Hospital. PARTICIPANTS: Adult patients admitted with post-tonsillectomy haemorrhage over a 2-year period. MAIN OUTCOME MEASURES: Temperature, white cell count, Neutrophil count and C-reactive protein. RESULTS: 47 patients were admitted with secondary post-tonsillectomy haemorrhage. Fifteen out of 47 patients (32%) had an elevated white cell count but in them the other indicators of temperature and C-reactive protein were extremely variable: none of these 15 patients was pyrexial (> 37.6 C). An elevated C-reactive protein was found in 55% of patients but none had an elevated white cell count. The elevated C-reactive protein may have been influenced by the recent surgery rather than infection. Overall there was no clear interrelation between the indicators of infection in the patients and none had the three main indicators of infection (pyrexia, increased white cell count and elevated C-reactive protein). CONCLUSIONS: Our results suggest that clinical signs of infection are lacking in patients with secondary tonsillectomy bleeding. Correspondingly the routine use of antibiotics should be questioned for secondary tonsillectomy haemorrhage.


Subject(s)
Postoperative Hemorrhage/etiology , Surgical Wound Infection/etiology , Tonsillectomy/adverse effects , Adolescent , Adult , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , C-Reactive Protein/metabolism , Female , Follow-Up Studies , Hemostatic Techniques , Humans , Injections, Intravenous , Leukocyte Count , Male , Middle Aged , Neutrophils/pathology , Postoperative Hemorrhage/epidemiology , Prospective Studies , Surgical Wound Infection/blood , Surgical Wound Infection/drug therapy , Treatment Outcome
19.
J Laryngol Otol ; 120(3): 244-6, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16372988

ABSTRACT

Interdigitating dendritic cell sarcomas (IDCSs) are extremely uncommon tumours that arise predominantly in lymphoid tissue. We report a case of an IDCS arising in the parotid gland of a 73-year-old man. Clinically, a primary salivary gland tumour was suspected but fine needle aspiration cytology suggested a soft tissue tumour. A diagnosis of IDCS was made on histopathological examination of the resection specimen, with subsequent confirmation by electron microscopy. Given the extreme rarity of this tumour at this site, it is unlikely to be a common diagnostic problem, but the importance of multiple diagnostic modalities is emphasized. The findings of cytology, histology, immunohistochemistry and electron microscopy have not previously been described together in a single case report of this tumour.


Subject(s)
Dendritic Cells/pathology , Parotid Neoplasms/pathology , Sarcoma/pathology , Aged , Humans , Male , Microscopy, Electron , Parotid Neoplasms/surgery , Sarcoma/surgery , Treatment Outcome
20.
Otolaryngol Head Neck Surg ; 133(2): 178-80, 2005 Aug.
Article in English | MEDLINE | ID: mdl-16087009

ABSTRACT

OBJECTIVES: The aim of study was to describe the histopathology in patients with unilateral sinus opacification and to identify variables that may predict neoplastic pathology. STUDY DESIGN: A retrospective review of paranasal sinus CT scans performed between 2000 and 2003 was conducted to identify patients with unilateral sinus opacification. RESULTS: Twenty-eight of 1118 CT scans showed unilateral sinus opacification. Twelve patients had neoplastic disease, 13 had inflammatory disease. Nasal discharge was more common in inflammatory than neoplastic disease (P = 0.009). A polyp or mass lesion was more common on nasendoscopy in neoplastic than inflammatory disease (P = 0.01). Bony erosion was only identified in malignant disease. CONCLUSION: A wide variety of pathologies present with unilateral sinus opacification on CT scanning. In our series, neoplastic disease was more associated with a visible polyp or mass lesion and less with nasal discharge. Bony erosion on CT scan was only seen in malignant disease. Histologic confirmation remains obligatory for diagnosis.


Subject(s)
Paranasal Sinus Diseases/diagnostic imaging , Paranasal Sinus Diseases/pathology , Tomography, X-Ray Computed/methods , Adult , Age Distribution , Aged , Aged, 80 and over , Cohort Studies , Endoscopy/methods , Female , Humans , Incidence , Male , Middle Aged , Nasal Obstruction/diagnostic imaging , Nasal Obstruction/pathology , Nasal Polyps/diagnostic imaging , Nasal Polyps/pathology , Paranasal Sinus Diseases/epidemiology , Probability , Retrospective Studies , Sensitivity and Specificity , Severity of Illness Index , Sex Distribution , Sinusitis/diagnostic imaging , Sinusitis/pathology
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