ABSTRACT
The efficacy of Mebendazole and Niclosamide was studied in two groups of 24 and 38 cases, respectively of patients suffering from taeniasis. Mebendazole with dose schedule of 200 and 300 mg twice daily for 3 consecutive days showed a cure rate of 71.42% and 92.30%, whereas Niclosamide at the dose rate of 200mg per patient was 94.76% effective. Flubendazole showed a cure rate of 66.66% only. Mebendazole and Niclosamide possess high taeniacidal activity, ability to reduce the clinical symptoms of taeniasis without any side effects. Niclosamide with high activity and excellent tolerance, is a drug of choice for the treatment of taeniasis in single dose treatment while for hymenolepsiasis it needs extended course.
Subject(s)
Antinematodal Agents/therapeutic use , Cestode Infections/drug therapy , Mebendazole/analogs & derivatives , Mebendazole/therapeutic use , Niclosamide/therapeutic use , Drug Administration Schedule , Drug Evaluation , Humans , Mebendazole/administration & dosage , Niclosamide/administration & dosage , Taeniasis/drug therapySubject(s)
Antiprotozoal Agents/therapeutic use , Dog Diseases/drug therapy , Phenanthridines/therapeutic use , Trypanosomiasis/veterinary , Animals , Dogs , Ethidium/administration & dosage , Ethidium/therapeutic use , Pyridinium Compounds/administration & dosage , Pyridinium Compounds/therapeutic use , Trypanosomiasis/drug therapyABSTRACT
The cation-exchange behaviour of 19 elements towards the strongly acidic cation-exchange resin Dowex 50-X8 in media containing varying concentrations of organic solvents and aqueous nitric acid is reported. Based on the determination of the distribution coefficients of these elements in the organic solvents methanol, ethanol, n-propanol, isopropanol, methyl glycol, acetone, tetrahydrofuran and acetic acid, the conditions most suitable for their quantitative separation are indicated and discussed.
ABSTRACT
In the present paper the cation-exchange characteristics of 20 elements towards the strongly acidic cation-exchange resin Dowex 50 X 8 in media containing varying concentrations of organic solvents and aqueous hydrochloric acid were investigated. Based on the determination of the distribution coefficients of these elements in the organic solvents methanol, ethanol, n-propanol, isopropanol, methyl glycol, acetone, tetrahydrofuran, and acetic acid, the conditions most suitable for their quantitative separation are indicated and discussed.
