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1.
Orthop J Sports Med ; 9(1): 2325967120972141, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33786333

ABSTRACT

BACKGROUND: Rugby is the fastest growing team sport in the United States for male and female athletes. It is a contact/collision sport with an injury risk profile that includes concussions. PURPOSE: To examine the prevalence of concussions in male and female rugby players in the United States and to characterize behaviors around reporting concussions that could be a target for prevention and treatment efforts. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: An online survey distributed to active members on the USA Rugby membership list was used to examine self-reported concussions in male and female athletes. Concussion-reporting behaviors and return to play after a concussion were also explored. Statistical analysis was used to compare male with female athletes and report differences, with years of experience as a dependent variable. RESULTS: The proportion of athletes with a history of at least 1 concussion was 61.9% in all respondents. Of those who reported a concussion, 50.8% reported the concussion during the game or practice in which it occurred, and 57.6% reported at least 1 concussion to a qualified medical provider. Overall, 27.7% of participants who reported ≥1 rugby-related concussion in our survey noted that at least 1 of these concussions was not formally reported. The most commonly cited reasons for not reporting a concussion included not thinking that it was a serious injury, not knowing that it was a concussion at the time, and not wanting to be pulled out of the game or practice. Additionally, 61.0% of athletes did not engage in recommended return-to-play protocols after their most recent rugby-related concussion. CONCLUSION: US rugby union athletes may not report concussions to medical personnel or follow return-to-play protocols guided by medical advice. This could result from a lack of education on concussion recognition and the risks associated with continued play after a concussion as well as limited access to health care. Further education efforts focusing on the identification of concussions, removal from play, and return-to-play protocols are necessary in the US rugby union population.

2.
Curr Oncol ; 25(4): 262-274, 2018 08.
Article in English | MEDLINE | ID: mdl-30111967

ABSTRACT

The annual Eastern Canadian Gastrointestinal Cancer Consensus Conference 2017 was held in St. John's, Newfoundland and Labrador, 28-30 September. Experts in radiation oncology, medical oncology, surgical oncology, and cancer genetics who are involved in the management of patients with gastrointestinal malignancies participated in presentations and discussion sessions for the purpose of developing the recommendations presented here. This consensus statement addresses multiple topics in the management of gastric, rectal, and colon cancer, including ■ identification and management of hereditary gastric and colorectal cancer (crc);■ palliative systemic therapy for metastatic gastric cancer;■ optimum duration of preoperative radiation in rectal cancer-that is, short- compared with long-course radiation;■ management options for peritoneal carcinomatosis in crc;■ implications of tumour location for treatment and prognosis in crc; and■ new molecular markers in crc.


Subject(s)
Colorectal Neoplasms , Canada , Colorectal Neoplasms/pathology , Consensus , History, 21st Century , Humans
3.
Bone Joint J ; 99-B(2): 245-249, 2017 Feb.
Article in English | MEDLINE | ID: mdl-28148668

ABSTRACT

AIMS: Advances in arthroscopic techniques for rotator cuff repair have made the mini-open approach less popular. However, the mini-open approach remains an important technique for repair for many surgeons. The aims of this study were to compare the integrity of the repair, the function of the shoulder and satisfaction post-operatively using these two techniques in patients aged > 50 years. PATIENTS AND METHODS: We identified 22 patients treated with mini-open and 128 patients treated with arthroscopic rotator cuff repair of July 2007 and June 2011. The mean follow-up was two years (1 to 5). Outcome was assessed using the American Shoulder and Elbow Surgeons (ASES) and Simple Shoulder Test (SST) scores, and satisfaction. The integrity of the repair was assessed using ultrasonography. A power analysis ensured sufficient enrolment. RESULTS: There was no statistically significant difference between the age, function, satisfaction, or pain scores (p > 0.05) of the two groups. The integrity of the repair and the mean SST scores were significantly better in the mini-open group (91% of mini-open repairs were intact versus 60% of arthroscopic repairs, p = 0.023; mean SST score 10.9 (standard deviation (sd) 1.3) in the mini-open group; 8.9 (sd 3.5) in arthroscopic group; p = 0.003). The ASES scores were also higher in the mini-open group (mean ASES score 91.0 (sd 10.5) in mini-open group; mean 82.70 (sd 19.8) in the arthroscopic group; p = 0.048). CONCLUSION: The integrity of the repair and function of the shoulder were better after a mini-open repair than after arthroscopic repair of a rotator cuff tear in these patients. The functional difference did not translate into a difference in satisfaction. Mini-open rotator cuff repair remains a useful technique despite advances in arthroscopy. Cite this article: Bone Joint J 2017;99-B:245-9.


Subject(s)
Minimally Invasive Surgical Procedures/methods , Rotator Cuff Injuries/surgery , Rotator Cuff/surgery , Aged , Aged, 80 and over , Arthroscopy , Female , Humans , Male , Middle Aged , Patient Satisfaction , Recovery of Function , Rotator Cuff/physiopathology , Rotator Cuff Injuries/physiopathology , Wound Healing
4.
Curr Oncol ; 23(6): e605-e614, 2016 Dec.
Article in English | MEDLINE | ID: mdl-28050151

ABSTRACT

The annual Eastern Canadian Gastrointestinal Cancer Consensus Conference 2016 was held in Montreal, Quebec, 5-7 February. Experts in radiation oncology, medical oncology, surgical oncology, and infectious diseases involved in the management of patients with gastrointestinal malignancies participated in presentations and discussion sessions for the purpose of developing the recommendations presented here. This consensus statement addresses multiple topics: ■ Follow-up and survivorship of patients with resected colorectal cancer■ Indications for liver metastasectomy■ Treatment of oligometastases by stereotactic body radiation therapy■ Treatment of borderline resectable and unresectable pancreatic cancer■ Transarterial chemoembolization in hepatocellular carcinoma■ Infectious complications of antineoplastic agents.

5.
Am J Orthop (Belle Mead NJ) ; 41(3): 132-9, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22530210

ABSTRACT

Physicians are exposed to occupational hazards of which they are often unaware. Orthopedic surgery has a particularly hazardous work environment in which surgeons are at increased risk for exposure to infection, radiation, smoke, chemicals, excessive noise, musculoskeletal injuries, as well as emotional and psychological disturbances. Understanding these risks and the precautions that can be taken to avoid them will help protect orthopedic surgeons from potential harm.


Subject(s)
Burnout, Professional/epidemiology , Occupational Exposure/adverse effects , Occupational Health , Orthopedic Procedures/adverse effects , Female , Humans , Infectious Disease Transmission, Patient-to-Professional/statistics & numerical data , Male , Orthopedic Procedures/methods , Primary Prevention/methods , Radiation Injuries/epidemiology , Radiation Injuries/etiology , Risk Assessment , Stress, Psychological
6.
Osteoarthritis Cartilage ; 17(10): 1327-32, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19410031

ABSTRACT

OBJECTIVE: This study tests the hypothesis that the natural progression of osteoarthritis (OA) in human joints leads to an increase in the friction coefficient. This hypothesis is based on the expectation that the wear observed in OA may be exacerbated by higher friction coefficients. A corollary hypothesis is that healthy synovial fluid (SF) may help mitigate the increase in the friction coefficient in diseased joints. DESIGN: The friction coefficient of human tibiofemoral joints with varying degrees of OA was measured in healthy bovine SF and physiological buffered saline (PBS). Two testing configurations were adopted, one that promotes sustained cartilage interstitial fluid pressurization to investigate the effectiveness of this mechanism with advancing OA, and another that allows interstitial fluid pressure to subside to investigate the effectiveness of boundary lubrication. RESULTS: Seven specimens were visually staged to be normal or mildly degenerated (stages< or =2 on a scale of 1 to 4) and nine others had progressive degeneration (stages>2 and< or =3). No statistical differences were found in the friction coefficient with increasing OA, whether in migrating or stationary contact area configurations; however, the friction coefficient was significantly lower in SF than PBS in both configurations. CONCLUSIONS: The friction coefficient of human tibiofemoral cartilage does not necessarily increase with naturally increasing OA, for visual stages ranging from 1 to 3. This outcome may be explained by the fact that interstitial fluid pressurization is not necessarily defeated by advancing degeneration. This study also demonstrates that healthy SF decreases the friction coefficient of OA joints relative to PBS.


Subject(s)
Cartilage, Articular/physiology , Friction , Knee Joint/physiology , Osteoarthritis, Knee , Synovial Fluid/physiology , Aged , Aged, 80 and over , Animals , Cattle , Female , Humans , Lubrication , Male , Middle Aged , Stress, Mechanical
8.
Am J Sports Med ; 29(3): 339-45, 2001.
Article in English | MEDLINE | ID: mdl-11394606

ABSTRACT

We compared anterior cruciate ligament function in skeletally mature patients after treatment of tibial eminence fractures with that of patients in two other groups: patients who had anterior cruciate ligament deficiency and patients who had undergone anterior cruciate ligament reconstruction using bone-patellar tendon-bone autografts. The Lysholm questionnaire was used to evaluate symptoms and KT-1000 arthrometry was used to determine objective knee laxity at an average follow-up of 5.2 years. Knee joint proprioception was assessed with a new method designed to test joint position sense. The Lysholm score for the tibial eminence group was 94 +/- 7. Only the patients in the anterior cruciate ligament-deficient group demonstrated statistically significantly increased laxity and inferior proprioception when the injured leg was compared with the uninjured leg. Both laxity and proprioception were statistically inferior for the anterior cruciate ligament-deficient group when compared with both the treated tibial eminence fracture group and the anterior cruciate ligament-reconstructed group. No statistically significant difference was observed between the anterior cruciate ligament-reconstructed and treated tibial eminence fracture groups. Correlation was observed between laxity and proprioception when all patients were analyzed. The results demonstrate that appropriate treatment of tibial eminence fractures restores stability and proprioception to the knee.


Subject(s)
Anterior Cruciate Ligament/physiopathology , Joint Instability/physiopathology , Tibial Fractures/physiopathology , Adolescent , Adult , Aged , Anterior Cruciate Ligament/surgery , Female , Fracture Fixation/methods , Humans , Male , Middle Aged , Proprioception , Plastic Surgery Procedures , Tibial Fractures/classification , Tibial Fractures/therapy
9.
Arthroscopy ; 17(5): 555-7, 2001 May.
Article in English | MEDLINE | ID: mdl-11337729

ABSTRACT

Patellar realignment procedures for lateral patellar instability often involve open approaches to imbricate the medial soft tissues. We present a technique to balance the soft tissues to correct lateral patellar instability that is performed entirely arthroscopically. A retinacular release is performed laterally and the soft tissues are imbricated medially using arthroscopic suture passing and knot tying techniques.


Subject(s)
Arthroscopy , Joint Instability/surgery , Patella/surgery , Humans , Suture Techniques
10.
Am J Sports Med ; 29(2): 201-6, 2001.
Article in English | MEDLINE | ID: mdl-11292046

ABSTRACT

This study characterizes the donor and recipient sites involved in osteochondral autograft surgery of the knee with respect to articular cartilage contact pressure, articular surface curvature, and cartilage thickness. Five cadaveric knees were tested in an open chain activity simulation and kinematic data were obtained at incremental knee flexion angles from 0 degrees to 110 degrees. Surface curvature, cartilage thickness, and contact pressure were determined using a stereophotogrammetry method. In all knees, the medial trochlea, intercondylar notch, and lateral trochlea demonstrated nonloadbearing regions. Donor sites from the distal-medial trochlea were totally nonloadbeadng. For the intercondylar notch, lateral trochlea, and proximal-medial trochlea, however, the nonloadbearing areas were small, and typical donor sites in these areas partially encroached into adjacent loadbearing areas. The lateral trochlea (77.1 m(-1)) was more highly curved than the typical recipient sites of the central trochlea (23.3 m(-1)), medial femoral condyle (46.8 m(-1)), and lateral femoral condyles (42.9 m(-1)) (P < 0.05). Overall, the donor sites had similar cartilage thickness (average, 2.1 mm) when compared with the typical recipient sites (average, 2.5 mm). The lateral trochlea and medial trochlea curvatures were found to better match the recipient sites on the femoral condyles, while the intercondylar notch better matched the recipient sites of the central trochlea. The distal-medial trochlea was found to have the advantage of being nonloadbearing. Preoperative planning using the data presented will assist in more conforming, congruent grafts, thereby maximizing biomechanical function.


Subject(s)
Bone Transplantation/methods , Cartilage/transplantation , Knee Joint/surgery , Tissue and Organ Harvesting/methods , Aged , Aged, 80 and over , Biomechanical Phenomena , Cadaver , Cartilage/pathology , Decision Making , Humans , Knee Joint/pathology , Middle Aged , Models, Biological , Tissue Transplantation/methods , Transplantation, Autologous , Weight-Bearing
11.
Am J Sports Med ; 28(6): 804-10, 2000.
Article in English | MEDLINE | ID: mdl-11101102

ABSTRACT

An open surgical repair of the injured medial patellar stabilizers, including the vastus medialis obliquus muscle and the medial patellofemoral ligament, after acute patellar dislocation was studied in eight patients. At initial examination, all patients had tenderness over the adductor tubercle and a positive patellar apprehension sign. Four of eight patients had obvious ecchymosis over the adductor tubercle. Magnetic resonance imaging, diagnostic arthroscopy, and open surgical exploration documented injury to both the medial patellofemoral ligament and the origin of the vastus medialis obliquus muscle. In all patients, the torn muscle was retracted in an anterior and superior direction and an arthroscopic lateral release was performed followed by open primary repair of the medial patellofemoral ligament to the adductor tubercle and repair of the vastus medialis obliquus muscle to the adductor magnus tendon. Patients were evaluated postoperatively with the Kujala scoring questionnaire. The average follow-up was 3.0 years, with a minimum of 1.5 years. No patients experienced a recurrent dislocation. The average Kujala score was 91.9. Patients rated their return to athletic activity at an average 86% of their pre-injury level. The average subjective satisfaction was 96%. In appropriate cases of acute patellar dislocation, we recommend primary repair of the medial patellofemoral ligament and the vastus medialis obliquus muscle to avoid recurrent dislocation, chronic subluxation, pain, and disability.


Subject(s)
Joint Dislocations/surgery , Patella/surgery , Adolescent , Adult , Female , Humans , Joint Dislocations/physiopathology , Magnetic Resonance Imaging , Male , Middle Aged , Muscle, Skeletal/surgery , Patella/physiopathology , Patellar Ligament/surgery , Surveys and Questionnaires , Treatment Outcome
12.
J Orthop Res ; 18(1): 101-8, 2000 Jan.
Article in English | MEDLINE | ID: mdl-10716285

ABSTRACT

Many clinical studies have emphasized the role of the hamstrings and the iliotibial band on knee mechanics, although few biomechanical studies have investigated it. This study therefore examined two hypotheses: (a) with loading of the hamstrings, the tibia translates posteriorly and rotates externally and the tibial contact pattern shifts anteriorly; furthermore, the changes in tibial kinematics alter patellar kinematics and contact; and (b) loading the iliotibial band alters the kinematics and contact pattern of the tibiofemoral joint similarly to loading the hamstrings, and loading the iliotibial band laterally translates the patella and its contact location. Five cadaveric knee specimens were tested with a specially designed knee-joint testing machine in an open-chain configuration. At various flexion angles, the knees were tested always with a quadriceps force but with and without a hamstrings force and with and without an iliotibial band force. The results support the first hypothesis. Hence, the hamstrings may be important anterior and rotational stabilizers of the tibia, a role similar to that of the anterior cruciate ligament. The results also support the second hypothesis, although the iliotibial band force had a smaller effect on the tibia than did the hamstrings force. Both forces also changed patellar kinematics and contact, demonstrating that these structures should also be considered during the clinical management of patellar disorders.


Subject(s)
Knee Joint/physiology , Aged , Aged, 80 and over , Biomechanical Phenomena , Female , Femur/physiology , Humans , Male , Middle Aged , Patella/physiology , Tibia/physiology
13.
Am J Sports Med ; 26(5): 715-24, 1998.
Article in English | MEDLINE | ID: mdl-9784821

ABSTRACT

The effects of patellar tendon adhesion on the knee extensor mechanism and on the kinematics and contact areas for both the patellofemoral and tibiofemoral joints were determined for five cadaveric knees in an open kinetic chain testing configuration. Patellar tendon adhesion decreased the distance from the inferior patellar pole to the tibial tuberosity, effectively creating patella infera. When compared with the controls, knees with adhesion had medial and distal translation of the patella, as well as increased patellar flexion. Although the patellar articular contact location shifted distally, the overall contact area did not change significantly. For the tibia, adhesion resulted in significant medial, proximal, and anterior translation, and internal rotation. Adhesion also resulted in a posterior shift of the tibial contact location. For the extensor mechanism, adhesion decreased the knee extension force created by the quadriceps muscle on the tibia, indicating a decrease in the effective moment arm of the extensor mechanism. Furthermore, as a result of patellar tendon adhesion, the angle formed by the quadriceps and patellar tendons decreased, suggesting an increase in patellofemoral joint reaction force with adhesion. The increased patellofemoral joint reaction force and the altered contact location may be related to anterior knee pain after knee trauma and knee surgery. Therefore, patients should be observed for subtle patella infera, which may indicate patellar tendon adhesion.


Subject(s)
Bone Diseases/physiopathology , Knee Joint/physiopathology , Musculoskeletal Diseases/physiopathology , Patellar Ligament/physiopathology , Tibia/physiopathology , Aged , Aged, 80 and over , Biomechanical Phenomena , Bone Diseases/pathology , Cadaver , Female , Femur/pathology , Femur/physiopathology , Humans , Knee Joint/pathology , Male , Middle Aged , Muscle Contraction/physiology , Muscle, Skeletal/pathology , Muscle, Skeletal/physiopathology , Musculoskeletal Diseases/pathology , Patella/pathology , Patella/physiopathology , Patellar Ligament/pathology , Range of Motion, Articular/physiology , Rotation , Stress, Mechanical , Tibia/pathology , Tissue Adhesions/pathology , Tissue Adhesions/physiopathology
14.
Orthopedics ; 21(7): 791-5, 1998 Jul.
Article in English | MEDLINE | ID: mdl-9672916

ABSTRACT

Twenty-one cadaveric knees were dissected to analyze the functional anatomy of the vastus medialis complex (VMC), which is composed of the vastus medialis obliquus (VMO) and the vastus medialis longus (VML) muscles. The physiologic cross-sectional area of the VMO for 20 of the knees was 29% of the total physiologic cross-sectional area for the VMC. These values differed in one knee with a dysplastic VMO. The quantitative description of the VMO provided by this study will facilitate future efforts to accurately model the physiologic function of the VMO in cadaveric investigations on patellofemoral mechanics. The effect of simulated pathologies and surgical reconstructions then may be determined with more certainty to improve patient management.


Subject(s)
Knee Joint/physiology , Knee/anatomy & histology , Muscle, Skeletal/anatomy & histology , Patella/physiology , Adult , Aged , Aged, 80 and over , Cadaver , Female , Humans , Knee/physiology , Male , Middle Aged , Muscle, Skeletal/physiology
15.
Indian J Pathol Microbiol ; 32(3): 161-6, 1989 Jul.
Article in English | MEDLINE | ID: mdl-2674005

ABSTRACT

One hundred and twenty two strains of E. coli isolated from clinical conditions of animals were studied for the production of colicins and their sensitivity behaviour towards 16 antibiotics and trimethoprim-sulphamethoxazole. Out of 122 strains, 27 (22.1%) were found colicinogenic and 25 (93%) of these colicinogenic strains were found resistant to one or more of drugs in various combinations. All the 27 colicinogenic strains could be typed into 15 serogroups. Serogroup 084 was found predominant. Transfer of R-plasmids and Col-plasmids were observed in 5 (18.5%) strains individually. In one strain both drug resistance and colicin production determinants were transferred enblock. Such transconjugants will be more invasive and virulent and will create serious chemotherapeutic problems.


Subject(s)
Colicins/biosynthesis , Escherichia coli/drug effects , Animals , Drug Resistance, Microbial/genetics , Escherichia coli/classification , Escherichia coli/metabolism , R Factors , Serotyping , Virulence
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