ABSTRACT
OBJECTIVE: To test the efficacy of double-fortified salt (DFS) on the anaemia and iodine deficiency (ID) status of women and their children. DESIGN: Double-blind randomised controlled trial. SETTING: Sekyere West District of Ghana. SUBJECTS: In this eight-month trial, mildly anaemic or non-anaemic, non-pregnant, non-lactating women were randomised into three groups receiving: DFS plus weekly placebo (n = 61); iodised salt plus weekly 70 mg iron supplement (n = 65); or iodised salt (IS) plus weekly placebo (control group, n = 58). Correspondingly, their mildly anaemic and non-anaemic children aged 1-5 years were randomised into two groups receiving either the DFS (n = 23) or IS alone (control group, n = 59). RESULTS: At the end of the intervention, prevalence of anaemia in women remained unchanged in the DFS or IS plus weekly iron supplement group, but significantly increased by 19.5% in the control group (P = 0.039). In children, prevalence of anaemia in the DFS group significantly decreased by 21.7% (P = 0.025) while no change was observed in the control group. ID decreased significantly in all groups of women (P < 0.001) and children (P < 0.05), with no difference among groups of women and children. CONCLUSION: While the use of DFS prevented anaemia in women, it had a significant role in both the prevention and treatment of anaemia in children. Both the DFS and IS significantly reduced ID in women and children to a similar degree.
Subject(s)
Anemia, Iron-Deficiency/prevention & control , Food, Fortified , Goiter, Endemic/prevention & control , Iodine/administration & dosage , Iron/administration & dosage , Rural Population , Sodium Chloride, Dietary/administration & dosage , Adolescent , Adult , Child , Female , Ghana/epidemiology , Humans , Iodine/deficiency , Middle AgedABSTRACT
Calf records on 621 West African Shorthorn (WASH) and 3 grades of Jersey x WASH crossbreds were analysed for the effects of the level of Jersey breeding and other factors on birth weight, 205-day weaning weight and average daily gain (ADG). Crossbred calves were significantly (P < 0.01) heavier at birth than purebred WASH and birth weights increased with increasing level of Jersey breeding. No significant differences were established for 205-day weaning weight, however ADG declined with increasing level of Jersey breeding suggesting possible problems of adaptation for calves of over 75% Jersey breeding. Age of dam effect was significant and linear (P < 0.0001) for birth weight and significant and quadratic (P < 0.01) for weaning weight and ADG, with values increasing from 3-year old dams to a peak in 7 year old dams.
