ABSTRACT
The aim of the study is to optimize laboratory diagnosis of urogenital chlamydiosis (UGH) in reproductive age women. 133 women 18-49 years old have been investigated. Colpitis were diagnosed in 43-40, 8% of patients, cervicitis and cervical pathology in 61-46,9%, PID in 59-45,4% .For diagnosis of UGH we use polymerase chain reaction (PCR) method. Results of investigation show, that analisis of urethral specimens together with cervical specimens increase the detection of Chlamydia trachomatis in 13,6%; performance of analysis in second phase of menstrual cycle increase the detection of Chlamydia trachomatis in 15,4%; use of magnitotherapy increase detection of Chlamydia trachomatis in 25%. We use magnitotherapy in cases of chronic UGC with reproductive function failure and /or suspicion of persistent form of UGH. For improvement of diagnosis of UGH in reproductive age women we recommend performing analysis taking specimens from urethra and cervix in second phase of menstrual cycle. In case of chronic UGH and /or suspicion of persistent form of UGH we recommend use of magnitotherapy and then analysis for chlamydial infection.
Subject(s)
Cervix Uteri/microbiology , Chlamydia Infections/diagnosis , Chlamydia trachomatis/isolation & purification , Female Urogenital Diseases/diagnosis , Menstruation/physiology , Ureter/microbiology , Adolescent , Adult , Chlamydia Infections/microbiology , Chlamydia trachomatis/radiation effects , Clinical Laboratory Techniques , Diagnosis, Differential , Female , Female Urogenital Diseases/microbiology , Humans , Magnetics , Middle Aged , Reproducibility of ResultsABSTRACT
The action of the synthetic polypeptide hormone angiotensin-II (A-II) on the ultrastructure of capillaries and perivascular glia of the cerebral cortex was studied in experiments on adult male rats. Intraperitoneal injections of the hormone are accompanied by swelling of the growing fibers and bodies of the precapillary glia (astrocytes), and by a strong narrowing of the capillary lumen. The endothelium of these vessels swells and layer inclusions appear in the cytoplasm of endothelial cells. The process is characterized by the growth of changes and reaches the maximum day 21 after the drug injections are started. The revealed changes in the pericapillary glia and capillary structure indicate microcirculatory disturbances in the cerebral cortex that may lead to trophic and functional abnormalities of the central nervous system.
