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1.
Arch Inst Pasteur Alger ; 57: 73-82, 1989.
Article in French | MEDLINE | ID: mdl-2489406

ABSTRACT

The prevalence of anti-Chlamydia antibodies was studied among 329 patients divided into 5 groups, 34 (36%) of the women with a low genital infection have antibodies at a titre greater than 16 versus 12 (17%) of the patients attending the women's clinic for routine pelvic examination. 44 (100%) of 44 prostitutes had antibodies greater than 16 meanwhile only 2 (7%) of 30 women attending an obstetric clinic had antibodies greater than 16. Titres suggesting active chlamydial infection were found in prostitutes (95%), women with low genital infection (17%) and patients attending a cancer screening clinic (11%). In other hand, using immunofluorescence test with monoclonal anti Chlamydia trachomatis antibodies, 20 (45.5%) of the prostitutes were found antigen positive.


Subject(s)
Chlamydia Infections/epidemiology , Chlamydia trachomatis/isolation & purification , Genital Diseases, Female/epidemiology , Adult , Algeria/epidemiology , Antibodies, Bacterial/analysis , Chlamydia trachomatis/immunology , Cross-Sectional Studies , Female , Genital Diseases, Female/microbiology , Humans , Mass Screening , Pregnancy , Pregnancy Complications, Infectious/microbiology , Prospective Studies , Random Allocation , Sex Work
2.
Virologie ; 38(4): 239-44, 1987.
Article in English | MEDLINE | ID: mdl-2449763

ABSTRACT

The prevalence of herpetic and chlamydial genital infections was studied in 309 women attending an outpatient gynecology clinic (Algiers, Algeria). Cell culture, IF on smears and Papanicolaou staining were the methods used for HSV diagnosis, serology by the MIF method and Papanicolaou staining were used for Chlamydia trachomatis diagnosis. The prevalence of herpetic genital infection was estimated at 7.2% by cell culture, 89% by IF method, and 3.9% using the Papanicolaou staining. Specific anti-Chlamydia trachomatis IgG with a titer greater than or equal to 16 were found in 35.7% out of 95 sera, and 18% out of the 95 women had an IgG titer greater than or equal to 64. If we consider IgG titer greater than or equal to 64 as significant for an active chlamydial genital infection, the concordance rate between the Papanicolaou staining and the MIF method is of 48%. However, the Papanicolaou method appears as insensitive for both the HSV and Chlamydia trachomatis diagnosis. The relative specificity of this method for HSV diagnosis accounts for its use as a screening test.


Subject(s)
Chlamydia Infections/epidemiology , Herpes Genitalis/epidemiology , Papanicolaou Test , Vaginal Smears/methods , Adult , Aged , Algeria , Cells, Cultured , Chlamydia Infections/diagnosis , Chlamydia trachomatis , Evaluation Studies as Topic , Female , Fluorescent Antibody Technique , Herpes Genitalis/diagnosis , Humans , Middle Aged , Staining and Labeling/methods
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