[The effect of metronidazole on the radiosensitivity of cancer of the uterine cervix]. / Vliianie metronidazola na radiochuvstvitel'nost' raka sheiki matki.

A comparative study of the effect of rectal administration of metronidazole on radiosensitivity of cervical cancer with relation to tumor sizes and a Hb level was conducted. The effect of a direct tumor reaction on survival was investigated. Rectal administration of metronidazole proved to be effective in large tumor sizes and a low Hb level. The use of metronidazole resulted in an increase in the number of patients with complete tumor regression and an increase in their survival. A low Hb level is an independent prognostic factor in radiation therapy of cervical cancer leading to an increase in tumor radiosensitivity.

[Intratumoral and parametric administration of metronidazole in the radiotherapy of cancer of the cervix]. / Vnutriopukholevoe i parametral'noe vvedenie metronidazola pri luchevoi terapii raka sheiki matki.

The paper is concerned with analysis of the results of radiation therapy of cervical cancer and intratumoral administration of metronidazole (124 patients with tumors, Stage IIB and III). At the end of the treatment, complete tumor regression in the intervention group (with metronidazole) was noted in 91% (irrespective of a stage of disease), in the control group (without metronidazole)--in 51% of the patients.