Data on prevalence and management practices of malaria-typhoid co-infection in Unwana South East Nigeria.

Using a descriptive survey design, the prevalence and management practices of malaria and malaria- typhoid co-infection in Unwana South East Nigeria was determined. Two hundred and thirty-six (236) febrile volunteers comprising 104 males and 132 females attending the Medical Centre of Akanu Ibiam Federal polytechnic Unwana, Afikpo Ebonyi state Nigeria participated in this study. Using thick film microscopy and Widal antigen-based agglutination test, one hundred and thirty-seven participants were diagnosed with malaria mono infection while ninety-nine were diagnosed with malaria-typhoid co-infection. Structured questionnaire was used to obtain data on the management practices and attitudes that constitute risk factors to increased incidence of treatment failure of malaria and malaria- typhoid co-infection. The dataset [1] is relevant as a baseline and reference for further research related to factors associated with increased risk of treatment failure and emergence of drug resistance of malaria and malaria-typhoid co-infection in resource poor setting.

In Vitro Element Bioavailability Studies of Some Underutilized Seeds in Southeast Nigeria.

Elemental and antinutritional compositions of three underutilized seeds (Mucuna sloanei, Brachystegia eurycoma and Detarium microcarpum) were analysed to elucidate their safety and wholesomeness as human food supplements or condiments using standard analytical methods. Results showed that there were significant differences in the concentration levels of the elements and the antinutrient contents of the seeds. The toxic element concentration levels clearly indicated that they exhibited acceptable values when compared with the recommended standards. There existed correlation between the contents of potassium, manganese, selenium and lead of the samples; calcium had inverse relationship with the oxalate contents, while lead and manganese had perfect association in all the samples. The results of elemental ratios showed synergistic interactions with exception of iron to zinc ratio in all the seeds. Element bioavailability in the presence of oxalate and phytate were all in tandem with the standard values. The results further revealed that zinc in all the seeds and selenium in Mucuna sloanei and Brachystegia eurycoma were overloaded in the samples, while the elemental safety index values for the other elements indicated that the seeds were safe. Overall, the findings of this study have strongly confirmed the nutritional potentials of these seeds and its safety and wholesomeness as human food condiments.

Risk Assessment of Metal(Loid)s Exposed to Infants via Consumption of Weaning Foods from Different Supermarkets in Sheffield, UK.

Infant complementary foods are readily available in the UK markets and nowadays, weaning mothers prefer feeding their babies with these products due to modern lifestyles. However, there is a dearth of research with respect to the health risk assessment of trace essential and potentially toxic elements in these products. Hence, this research investigated the health risks of trace essential and potentially toxic elements exposed to infants via consumption of these complementary foods during the first 4 to 12 months of life. Levels of trace essential and potentially toxic elements were determined using inductively coupled plasma mass spectrometer, daily intakes were estimated using the Food Agricultural Organization/World Health Organization and manufacturer food consumption regime while the US Environmental Protection Agency guideline was used to estimate target hazard quotient and carcinogenic health risk indices. The levels of the elements in the foods varied and were within the safe limits recommended by food standard agencies. The results also showed that the estimated daily intakes of these elements were below the reference doses stipulated by food regulatory agencies. The target hazard quotients and the total carcinogenic risks of the elements in the infant foods were less than 1 and 1.0E-04, respectively, signifying that the target groups may not experience adverse non-carcinogenic and carcinogenic health effects because of these foods. This study will be quite helpful for weaning mothers, infant food production and processing companies and government officials in taking protective measures for reducing elemental contamination in infants' complementary foods.

Mineral compositions of infant complementary foods in relation to dietary daily intake and synergistic/antagonistic interrelationships.

This study investigated the levels of selected essential elements in a brand of industrially prepared complementary foods in the UK for infants aged 4+, 7+, and 10+ months in order to ascertain their nutritional standards relative to the mineral reference daily intakes and interrelationships. Estimated daily intake of minerals was calculated from elemental contribution from the complementary foods and breast milk. The results showed remarkable significant differences (p < .05) in the concentration levels of the elements in the complementary foods. There were no significant differences (p > .05) between the estimated daily intakes compared to the standard values stipulated by the regulatory bodies. Although, the results showed that specific interrelationships were generally justified by the elemental contents, there were few differences with respect to the overall elemental profile. The results of the study support the recommendation of the use of semi-pureed meals by infants as complementary foods. However, the results of mineral interrelationships implicated imbalances and thus recommend fortification of the infants' complementary foods with iron, calcium, and zinc.