Noise Exposure and Hearing Loss among Brewery Workers in Lagos, Nigeria.

The health risks of exposure to loud noises are a well-established fact and are widely addressed in modern industries. Yet, in less developed countries, it is thought these hazards receive less attention, both in the workplace and in private life. (1) Background: The aim of this study is to assess the occupational noise exposure in a developing country and identify possible risk groups for whom intervention is needed. (2) Methods: A cross-sectional study was performed among brewery employees in Lagos, Nigeria. Pure-tone audiometry (PTA) was performed, paired with a self-report questionnaire. Personal noise dosimetry (PND) was also performed with an additional group of participants. (3) Results: A total of 458 employees were submitted to PTA. The Packaging and Utilities department reported the largest shifts in hearing thresholds (18 dB [sd = 15] and 16 dB [sd = 15] @4kHz, respectively). No significant effect of department type on auditory health could be found. PND results were obtained from 39 employees. Packaging and Sales were identified as the most exposed departments. (4) Conclusions: A healthy hearing profile was found for a large proportion of the brewery employees (91.7%). However, NIHL (noise-induced hearing loss) proportions specifically among Bottling and Sales employees were elevated.

Ethical Issues in the Practice of Assisted Reproductive Technologies in Nigeria: Empirical Data from Fertility Practitioners.

The need to formulate practice guidelines and ethical framework to guide the practice of assisted conception in Nigeria has been highlighted severally. The Association for Fertility and Reproductive Health (AFRH) ethics committee is charged with the objective of producing ethical guidelines that would govern the practice of assisted conception in Nigeria. This study was a survey of attendees at the AFRH international conference that held in Abuja in September 2017. The aim of the study was to generate empirical data that would form the drafting of ethical practice guidelines in Nigeria. Ninety-seven (50%) of the respondents were of the view that performing IVF for unmarried couples was ethical while about 70 (36%) were of the contrary opinion. Respondents were equally divided (45.26% versus 44.21%) on the ethical standing of performing IVF for single ladies. About 128 (70.33%) of respondents agree that egg donors should be paid more in compensation besides reimbursement for personal expenditure incurred during the process of egg donation and that they should be an upper age limit for clients requesting ART with donor eggs. Several unethical practices ongoing in Nigeria were highlighted including inadequate provision of information and counselling and exploitation of egg donors. Majority agreed on the need for a regulatory framework to govern the practice of ART in Nigeria. The diverse range of views and ethical issues concerning ART practice in Nigeria obtained from this study demonstrates the need to recognise the local context in Nigeria when applying universal principles of ethics.

Predictive value of the number of oocytes retrieved at ultrasound-directed follicular aspiration with regard to fertilization rates and pregnancy outcome in intracytoplasmic sperm injection treatment cycles.

OBJECTIVE: To determine the number of oocytes sufficient for satisfactory fertilization and pregnancy rates in intracytoplasmic sperm injection cycles. DESIGN: A retrospective analysis. SETTING: A private assisted conception unit. PATIENT(S): Women in whom at least one oocyte was retrieved in consecutive ultrasound-directed follicular aspirations between June 1999 and June 2001. INTERVENTION(S): Standard protocol for pituitary down-regulation and ovarian stimulation. MAIN OUTCOME MEASURE(S): Number of oocytes retrieved, embryos transferred, fertilization, and pregnancy rates. RESULT(S): The numbers of oocytes obtained per cycle were classified into groups A, B, C, and D, consisting of 110, 124, 96, and 122 cycles, with 1-5, 6-10, 11-15, >15 oocytes retrieved from each patient in each group, respectively. The chance of not obtaining a viable oocyte for injection was highest in group A (5.5%). Most fertilization failures occurred in group A (11.8%). Total cleavage failure occurred in the greatest percentage of cycles in group A (3.6%) with a significantly lower mean number of embryos (1.9 +/- 1.7) being transferred. The clinical pregnancy rate was also lowest in group A (7.1%) compared with groups B (25.8%), C (20.8%), and D (23.8%). CONCLUSION(S): Retrieval of between 6 and 10 oocytes per patient and transfer of a maximum of three cleavage-stage embryos results in high pregnancy rates.