ABSTRACT
High pollution and low productivity of the traditional method for synthesis of vitamin group K require an efficient, low-cost, and environmentally sustainable biocatalyst as a greener process. These have encouraged us to design and fabricate a series of novel Co NPs impregnated pectin-gelatin (Co@PTNC, Co@GTNC & Co@PT0.7GT0.3NC) and grafted pectin-gelatin modified magnetic beads (Co@MPT0.7GT0.3NC) by the in situ reduction-precipitation procedure and chemical application in the selective synthesis of vitamin K3 without any promoters or ligands. The chemical structure and morphological properties were fully characterized. Additionally, the influence of structural parameters (i.e., kind of stabilizer with different ratio (nPT/nGT), amount of Co loading, durability, size, distribution, and Leaching test) and operating parameters (i.e., reaction time, reaction temperature, nature of the solvent, and concentration of oxidant) on the efficacy of the biocatalysts was evaluated in detail. The green synthesis involves several advantages, like the heterogeneous nature of catalysts, environmentally-friendly and mild conditions, high recovery efficiency due to superparamagnetism, high activity, and the sustainable performance of the biocatalyst.
