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1.
BMJ Case Rep ; 16(5)2023 May 31.
Article in English | MEDLINE | ID: mdl-37258048

ABSTRACT

We received a call from a transplant coordinator about the availability of a consented deceased donor. En-bloc kidneys with the aorta and IVC (inferior vena cava) were harvested from a toddler weighing 8 kg. The recipient was of early childhood weighing 14 kg who had been on haemodialysis for the last 3 years for end-stage kidney disease. He received anti-thymocyte globulin as an induction immunosuppressant. The kidneys were transplanted en bloc in the right lower quadrant retroperitoneal region; an anastomosis was performed to the recipient's aorta and IVC, and two separate neocystoureterostomies were created. His serum creatinine reached 0.5 mg/dL on the seventh postoperative day, following a few days of delayed graft function. In this study, we describe the surgical and non-surgical challenges that we faced while performing en-bloc kidney transplant to the youngest recipient and how a multidisciplinary team approach helped us overcome them.


Subject(s)
Kidney Failure, Chronic , Kidney Transplantation , Male , Humans , Child, Preschool , Kidney , Kidney Failure, Chronic/surgery , Vena Cava, Inferior , Tissue Donors
2.
BMJ Case Rep ; 16(3)2023 Mar 22.
Article in English | MEDLINE | ID: mdl-36948521

ABSTRACT

An early adolescent boy with chronic kidney disease on haemodialysis was referred to the surgical clinic for the creation of an arteriovenous fistula. He was undergoing treatment for dilated cardiomyopathy and extrapulmonary tuberculosis. The patient was haemodynamically stable during the procedure, but he developed rapidly progressing dyspnoea, tachycardia and tachypnoea about 10 min after the vessels were declamped. His blood pressure rapidly rose above 220/120 mm Hg and saturation dropped below 90%. A multidisciplinary team (MDT) constituted of surgeons, nephrologists and intensivists was quickly activated. The patient was put on a mechanical ventilator and resuscitated with parenteral antihypertensives, diuretics, amiodarone and haemodialysis. The patient improved clinically and was discharged on the third postoperative day. Thus, a rapidly activated MDT approach was key in breaking the vicious cycle caused by hypertensive crisis, myocardial dysfunction and impending ventilatory failurethat occurred following access surgery.


Subject(s)
Arteriovenous Fistula , Arteriovenous Shunt, Surgical , Kidney Failure, Chronic , Pulmonary Edema , Male , Adolescent , Humans , Kidney Failure, Chronic/therapy , Pulmonary Edema/diagnosis , Pulmonary Edema/etiology , Pulmonary Edema/therapy , Arteriovenous Shunt, Surgical/adverse effects , Renal Dialysis/adverse effects , Renal Dialysis/methods , Arteriovenous Fistula/etiology , Arteriovenous Fistula/therapy , Treatment Outcome
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