ABSTRACT
Experiments were carried out on 35 lambs infected with echinococcus eggs taken from canine donors, 5 lambs with echinococcosis, 5 lambs with echinococcosis + paecilomycosis, 5 lambs with coenurosis, 5 with cysticercosis ovis, 5 with alveococcosis, 5 with paecilomycosis, inoculated by the material taken from patients; and 5 healthy lambs formed a control group. Cystic hydatidosis was found to induce substantial cardiovascular changes.
Subject(s)
Coinfection , Echinococcosis , Liver , Lung , Paecilomyces , Amino Acids/blood , Animals , Animals, Domestic/blood , Animals, Domestic/microbiology , Animals, Domestic/parasitology , Animals, Wild/blood , Animals, Wild/microbiology , Animals, Wild/parasitology , Birds/microbiology , Birds/parasitology , Echinococcosis/blood , Echinococcosis/parasitology , Echinococcosis/veterinary , Echinococcus/isolation & purification , Humans , Liver/microbiology , Liver/parasitology , Liver/pathology , Lung/microbiology , Lung/parasitology , Lung/pathology , Mycoses/blood , Mycoses/epidemiology , Mycoses/veterinary , Paecilomyces/isolation & purification , Paecilomyces/pathogenicitySubject(s)
Echinococcosis, Hepatic/microbiology , Echinococcosis, Hepatic/surgery , Mycoses/drug therapy , Mycoses/metabolism , Myocarditis/drug therapy , Myocarditis/microbiology , Paecilomyces/isolation & purification , Adolescent , Child , Child, Preschool , Female , Humans , Male , Mycoses/parasitology , Myocarditis/parasitology , RussiaABSTRACT
Experiments have established that the first target for echinococcus is the liver and lung and that for pathogenic fungi and protozoa is the heart. Adult patients with hepatic hydatid disease complicated by paecilomycosis have been found to have atypical paecilomycosis-associated myocarditis, the treatment of which was developed by the authors, by using antibiotics, fungicides, and homeopathic remedies.
Subject(s)
Echinococcosis/complications , Heart/physiopathology , Mycoses/complications , Myocarditis/complications , Sarcocystosis/complications , Adult , Aged , Animals , Anti-Bacterial Agents/therapeutic use , Antifungal Agents/therapeutic use , Coinfection , Echinococcosis/drug therapy , Echinococcosis/parasitology , Echinococcus/drug effects , Echinococcus/physiology , Female , Heart/drug effects , Heart/microbiology , Heart/parasitology , Humans , Liver/drug effects , Liver/microbiology , Liver/parasitology , Lung/drug effects , Lung/microbiology , Lung/physiopathology , Male , Materia Medica/therapeutic use , Middle Aged , Mycoses/drug therapy , Mycoses/microbiology , Myocarditis/drug therapy , Myocarditis/microbiology , Myocarditis/parasitology , Paecilomyces/drug effects , Paecilomyces/physiology , Sarcocystis/drug effects , Sarcocystis/physiology , Sarcocystosis/drug therapy , Sarcocystosis/parasitologyABSTRACT
The authors have detected atypical paecilomycosis-associated myocarditis with impaired amino acid exchange and pain syndrome for the first time. At first, pain occurs in the chest and radiates into the axilla, to the left arm to the finger tips, by paralyzing the arm. In some patients, pain manifests itself in both arms with radiation to the belly, by accompanying by fainting. The skin is wet, cold; the pulse is frequent and of poor volume and difficult-to-count. Heart pain spreads into the armpit and down the arm, by making the fingers numb. Attempts to use current analgesics (movalis, sirdalud, nimesil, morphine) in combination with fungicides (diflucan, mycosist, orungal) have failed to yield positive results. The homeopathic drug Latrodectus mactans, prepared from caracurt venom, in combination with the authors' designed diet and other homeopathic agents have relieved pain syndrome and normalized amino acid exchange, which offered possibilities for successful surgical treatment for echinococcosis with later recovery.
Subject(s)
Amino Acids/metabolism , Echinococcosis/blood , Echinococcus/physiology , Materia Medica/therapeutic use , Mycoses/blood , Paecilomyces/growth & development , Spider Venoms/therapeutic use , Adolescent , Adult , Aged , Analgesics/administration & dosage , Animals , Black Widow Spider/chemistry , Diet , Echinococcosis/complications , Echinococcosis/diagnosis , Echinococcosis/drug therapy , Echinococcosis/parasitology , Echinococcosis/surgery , Echinococcus/drug effects , Female , Fluconazole/administration & dosage , Humans , Liver/drug effects , Liver/metabolism , Liver/parasitology , Liver/surgery , Male , Materia Medica/administration & dosage , Middle Aged , Mycoses/complications , Mycoses/diagnosis , Mycoses/drug therapy , Mycoses/microbiology , Myocarditis/complications , Paecilomyces/drug effects , Pain/complications , Spider Venoms/chemistryABSTRACT
A total of 117 children with chronic pyelonephritis (CP) aged 4-14 were examined and treated. 57 of them having attendant cystitis received multimodality treatment comprising local intravesicular instillations of chigain controlled by clinical findings, urinalysis, cystoscopy and urinary secretory immunoglobulins SIg A1, SIg A2 and IgG. The drug chigain capable of immune replacement was found to initiate clinical response, positive trends in urinalysis and cystoscopy data, in the levels of secretory urine immunoglobulins. The findings show the need of immune replacement therapy in the complex of modalities to treat children with CP combined with cystitis.
