Formation and some cytophysiological characteristics of polynuclear macrophages in primary cultures of peritoneal cells.

We studied the formation and cytophysiological characteristics of polynuclear macrophages in primary cultures of peritoneal cells from C57Bl/6 mice. Production of reactive oxygen species and phagocytic activity in polynuclear macrophages were higher than in mononuclear macrophages. The formation of polynuclear macrophages in cultures of peritoneal cells is realized via amitosis.