ABSTRACT
The authors studied allostatic load in railway workers, as an indicator of stress effect. Analysis covered biomarkers that form allostatic load index, and their ratio for variable allostatic load index levels. Moderate allostatic load appeared to prevail in the examinees group. Findings are that systolic and diastolic blood pressure, general cholesterol and hemoglobin make major contribution into allostatic load index. Comparison covered models of allostatic load index calculation for variable biomarkers sets.
Subject(s)
Allostasis/physiology , Biomarkers , Occupational Diseases/physiopathology , Railroads , Stress, Psychological/physiopathology , Adult , Humans , Male , Middle Aged , Occupational Diseases/bloodABSTRACT
The study covered influence of Melaxene on human brain functional state. Complex dynamic (12-hour) neurophysiologic study revealed that single dose of Melaxene (3 mg) influences brain functional state--reliably increases cross-correlation parameters of global spatial synchronization of cortex biopotentials in various ranges of EEG rhythms. Analysis of functional asymmetry of spatial synchronization of cortex biopotentials in various brain areas proved that Melaxene acitvates important cross-correlation links in spatial synchronization of cortex biopotentials in left and right brain hemispheres, with dominated activity of left hemisphere.
