ABSTRACT
To compare hospital mortality and postoperative complications in patients with severe coronary artery disease undergoing coronary artery bypass grafting with or without coronary endarterectomy, 100 consecutive patients were divided into 2 groups of 50 patients each. Group 1 had coronary endarterectomy, and group 2 had no coronary endarterectomy. There were 87 men and 13 women, with a mean age of 54.79 +/-7.8 years; 48% had stable angina. The right coronary artery was endarterectomized in 22 patients, the left anterior descending artery in 21, and the left circumflex in 7. There were no significant differences in outcomes. There was 1 hospital death in each group. Perioperative myocardial infarction occurred in 2 patients in group 1 and 1 in group 2. Endarterectomy is a suitable option to achieve complete revascularization in patients with refractory angina and severe diffuse disease.
Subject(s)
Coronary Artery Bypass/mortality , Coronary Artery Disease/mortality , Coronary Artery Disease/surgery , Endarterectomy/mortality , Hospital Mortality , Angina Pectoris/mortality , Angina Pectoris/surgery , Female , Humans , Incidence , Male , Middle Aged , Myocardial Infarction/mortality , Myocardial Infarction/surgery , Postoperative Complications/mortality , Prospective Studies , Randomized Controlled Trials as Topic , Risk FactorsABSTRACT
To assess long-term survival and anticoagulant-related complications after mechanical valve replacement in adolescents with rheumatic heart disease, 88 patients aged Subject(s)
Anticoagulants/therapeutic use
, Heart Valve Diseases/surgery
, Heart Valve Prosthesis Implantation
, Rheumatic Heart Disease/surgery
, Adolescent
, Anticoagulants/adverse effects
, Child
, Female
, Follow-Up Studies
, Heart Valve Diseases/mortality
, Heart Valve Prosthesis
, Heart Valve Prosthesis Implantation/adverse effects
, Heart Valve Prosthesis Implantation/instrumentation
, Hemorrhage/chemically induced
, Hospital Mortality
, Humans
, Kaplan-Meier Estimate
, Male
, Prospective Studies
, Prosthesis Design
, Rheumatic Heart Disease/mortality
, Stroke/etiology
, Stroke/mortality
, Stroke/prevention & control
, Thrombosis/etiology
, Thrombosis/mortality
, Thrombosis/prevention & control
, Time Factors
, Treatment Outcome
ABSTRACT
Anticoagulation in pregnancy was evaluated in 33 women with a mechanical heart valve prosthesis who had 53 pregnancies between 1994 and 2006. Their mean age at valve operation was 24.4 +/- 5.4 years, and 22 (67%) had isolated mitral valve disease. Of these patients, 22 had a single pregnancy, 5 had 2 pregnancies, 3 had 3, and 3 had 4. In 43 pregnancies, the patients took warfarin throughout; in the other 10, heparin was used in the first trimester followed by warfarin until the last 15 days. Mean international normalized ratio and warfarin levels before, during, and after pregnancy were similar. Complications occurred in 3 (6%) women who had thrombosed valves: 2 (20%) in the heparin group and 1 (2%) who had warfarin only. Live births resulted from 37 (70%) pregnancies. There were significantly more abortions in the heparin group (6; 60%) than the warfarin group (8; 19%). Hemorrhage requiring transfusion occurred in 2 (5%) patients in the warfarin group. All live births resulted in healthy babies. It was concluded that anticoagulation with warfarin is safe during pregnancy in women with mechanical heart valves.
Subject(s)
Anticoagulants/therapeutic use , Heart Valve Prosthesis Implantation/adverse effects , Heparin/therapeutic use , Pregnancy Complications, Cardiovascular/prevention & control , Thrombosis/prevention & control , Warfarin/therapeutic use , Abortion, Spontaneous/chemically induced , Administration, Oral , Adult , Anticoagulants/administration & dosage , Anticoagulants/adverse effects , Drug Administration Schedule , Female , Heart Valve Prosthesis , Heart Valve Prosthesis Implantation/instrumentation , Hemorrhage/chemically induced , Heparin/administration & dosage , Heparin/adverse effects , Humans , Pakistan , Patient Selection , Practice Guidelines as Topic , Pregnancy , Prospective Studies , Prosthesis Design , Risk Assessment , Thrombosis/etiology , Time Factors , Treatment Outcome , Warfarin/administration & dosage , Warfarin/adverse effectsABSTRACT
Household poisons can cause serious damage to the health of children. Turpentine oil, used chiefly as a solvent in paints, varnishes, and waxes; is often placed within easy reach of children during polishing or painting work. It is capable of causing serious toxicity, whether ingested or inhaled. Pulmonary aspiration can lead to lung parenchymal damage and turpentine-associated pneumonia. We report a case of exploratory ingestion and inhalation of turpentine oil in an 18-month-old boy, leading to extensive lung parenchymal damage, formation of multiple abscess cavities, and necrosis treated with decortication and segmental resection.
