ABSTRACT
UNLABELLED: This study was initiated to determine the progression of the cardiovascular risk (CR) in a 5-years period for those who went through high blood pressure treatment. It is a retrospective and descriptive study over a period of 9 years. Were included in that category, African patients treated in that period of time and who at least benefited from a 5-years medical care period. The total CR was calculated afterwards, for the needs for the study, using the tables of Framingham. All the data were collected after the first evaluation then brought up to date at the terms of 1, 3 and 5 years and with a last consultation for the patients whose medical care follow-up exceeded 5 years. For the 103 patients who had complete data, the average age was of 49.11±8 and the sex ratio of 2. Among them 14 (13.6%) died of cardiovascular complications. Among the 89 remaining patients, the CR at the beginning was very high in a proportion of 10.1%, high in 49.4%, moderated in 22.5% and weak in 18%. The general evolution is characterized by a stability of the proportion of the moderated CR (20 - 23%) and high CR (43 - 50%) but a very important increase in the proportion of the very high CR (10 to 21%) to the detriment of the weak CR (18 to 10%). The analysis of the individual evolution reveals an improvement of the CR among 19 patients (21.3%), its stability among 39 patients (43.8%) and a worsening among 31 patients (34.8%). These data are confirmed in a widened population of 321 patients of which the less complete data allow an estimate of the CR. CONCLUSION: The cardiovascular risk is difficult to evaluate. It is badly controlled in the long run.
Subject(s)
Black People , Cardiovascular Diseases/diagnosis , Cardiovascular Diseases/epidemiology , Developing Countries , Hypertension/diagnosis , Hypertension/epidemiology , Adult , Antihypertensive Agents/therapeutic use , Benin , Cardiovascular Diseases/mortality , Cardiovascular Diseases/prevention & control , Cause of Death , Cross-Sectional Studies , Disease Progression , Female , Hospitals, Military , Hospitals, Teaching , Humans , Hypertension/drug therapy , Hypertension/mortality , Longitudinal Studies , Male , Middle Aged , Retrospective Studies , Risk FactorsABSTRACT
The aim of this study is to evaluate the frequency of protein C deficiency in venous thromboembolism in black African patients of Benin. It is a descriptive study. Inclusion criteria were: acceptance- having a venous thromboembolism. No exlusion criteria was retained. Protein C deficiency was diagnosed by quantitative technic with a Minividas materiel in the blood. Protein C dosage has been done before antivitamin k therapy and a second dosage has been done if the first one demonstrated a low level of protein C. Acuired aetiology have been research. For the 54 patients of this study mean age was 52.7±14.1 and sex-ratio 1.08. The frequency of protein C deficiency was 9.3% in all patients and 12.5% in those with clinical thrombophily (p=1). No acquired deficit has been found.
Subject(s)
Black People , Developing Countries , Protein C Deficiency/diagnosis , Protein C Deficiency/ethnology , Venous Thromboembolism/diagnosis , Venous Thromboembolism/ethnology , Adult , Aged , Benin , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Prospective Studies , Protein C Deficiency/drug therapy , Protein C Deficiency/epidemiology , Risk Factors , Venous Thromboembolism/drug therapy , Venous Thromboembolism/epidemiology , Vitamin K/antagonists & inhibitorsSubject(s)
Atherosclerosis/epidemiology , Carotid Artery Diseases/epidemiology , Diabetic Angiopathies/epidemiology , Adult , Aged , Benin , Female , Humans , Male , Middle AgedABSTRACT
L'objectif de cette etude est de depister le deficit en proteine C dans une population de patients noirs africains atteints de maladie thromboembolique veineuse. C'est une etude descriptive transversale qui a inclus systematiquement tous les patients hospitalises pour MTEV aigue ou suivis dans les suites de MTEV qui ont accepte d'y participer. Un dosage quantitatif de la proteine C a ete realise sur un equipement de type Minividas. Le prelevement sanguin a ete effectue en dehors de tout traitement antivitamine K. Un deuxieme prelevement est effectue pour confirmation au cas ou le premier dosage affirme un deficit. En cas de deficit la recherche d'une etiologie acquise est systema- tique. Pour les 54 patients retenus la sex-ratio etait de 1;08 et l'age moyen est de 52;7+/- 14;1 ans. Un deficit en proteine C a ete diagnostique chez 9;3des patients et 12;5des patients presentant des criteres de thrombophilie ( p=1). Aucune etiologie acquise n'a ete mise en evidence
