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1.
Thorac Cardiovasc Surg ; 59(5): 293-7, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21544788

ABSTRACT

OBJECTIVE: The term "subaortic stenosis" includes a variety of obstructions of the left ventricular outflow tract (LVOT), ranging from a short (discrete) subvalvular membrane to long, tunnel-like narrowing. An association with other congenital lesions is frequent. We reviewed the reported literature and describe our results, analyzing the nomenclature of and risk factors for restenosis after surgical treatment. METHODS: From 1994 to 2009, 81 children (53 males, 28 females; median age: 57 months, range [ R]: 5-204) underwent surgical relief of a subaortic stenosis. Patients were divided, according to pathology, into short segment (group A, n = 42) and complex obstructions (group B, n = 39), with the latter including long segment stenosis and/or associated anomalies such as aortic coarctation, interrupted aortic arch or Shone's complex. RESULTS: Surgery resulted in a significant reduction of the gradient between the left ventricle and the aorta in both groups (Δ P group A: 51 ± 28 mmHg, group B: 46 ± 25 mmHg). There was no operative mortality. One patient died in the early postoperative period due to pericardial tamponade. Median follow-up was 90 months (R = 0.5-187). Twenty-five (31%) patients required reoperation because of recurrent stenosis after a median of 43 months (R = 0.5-128). Seven (16%) patients belonging to group A developed restenosis, and 18 (46%) in group B. Freedom from reoperation for all patients was 60% after 10 years. 10 (40%) of the patients of group B were ultimately treated with a Ross-Konno reconstruction of the LVOT. CONCLUSION: Despite adequate surgical resection, recurrence of subaortic stenosis within several years after initial surgical treatment is frequent, especially in patients with complex lesions. In cases requiring reoperation, the surgical therapy is often extensive, and even includes Ross-Konno reconstruction of the LVOT.


Subject(s)
Aortic Stenosis, Subvalvular/surgery , Cardiac Surgical Procedures , Discrete Subaortic Stenosis/surgery , Ventricular Outflow Obstruction/surgery , Adolescent , Aortic Stenosis, Subvalvular/classification , Aortic Stenosis, Subvalvular/diagnosis , Aortic Stenosis, Subvalvular/mortality , Aortic Stenosis, Subvalvular/physiopathology , Cardiac Surgical Procedures/adverse effects , Cardiac Surgical Procedures/mortality , Chi-Square Distribution , Child , Child, Preschool , Discrete Subaortic Stenosis/classification , Discrete Subaortic Stenosis/diagnosis , Discrete Subaortic Stenosis/mortality , Disease-Free Survival , Female , Germany , Humans , Infant , Kaplan-Meier Estimate , Male , Recurrence , Reoperation , Risk Assessment , Risk Factors , Terminology as Topic , Time Factors , Treatment Outcome , Ventricular Outflow Obstruction/classification , Ventricular Outflow Obstruction/diagnosis , Ventricular Outflow Obstruction/mortality , Ventricular Outflow Obstruction/physiopathology
2.
Pediatr Cardiol ; 26(1): 93-6, 2005.
Article in English | MEDLINE | ID: mdl-15793660

ABSTRACT

Three patients (ages 3, 5, and 8 years) with various forms of functionally univentricular heart lesions received a total cavopulmonary connection with an extracardiac conduit as a final reconstructive procedure. Failure of the Fontan circulation occurred immediately after surgery because of spontaneous closure of surgical fenestrations in two children and absent fenestration in one. As an emergency procedure, in all patients the conduit was perforated by transcatheter intervention in order to create a connection to the anatomical right atrium. Following balloon dilatation of the perforated conduit, in all three patients covered stent grafts were placed in the newly created defect to attain a reliable communication. Patency of the fenestration was demonstrated by angiogram and any leakage was ruled out. Cardiac output improved and severe pleural effusion and ascites subsided. Right-to-left shunt could be demonstrated by echocardiography at follow-up after 7 months (median) in all three patients. Oxygen saturation remained stable between 85 and 90%. These preliminary results suggest that stent graft fenestration can serve as a valuable tool in failing Fontan circulation, particularly in patients with an extracardiac conduit. Covered stents have the potential to reduce the acute risk of bleeding and they help to prevent early spontaneous closure of the newly created fenestration.


Subject(s)
Blood Vessel Prosthesis Implantation , Cardiac Output, Low/surgery , Fontan Procedure , Stents , Cardiac Catheterization , Cardiac Output , Catheterization , Child , Child, Preschool , Coronary Angiography , Humans , Infant , Male , Pleural Effusion/surgery , Radiography, Interventional
3.
Heart ; 89(6): 645-50, 2003 Jun.
Article in English | MEDLINE | ID: mdl-12748222

ABSTRACT

OBJECTIVE: To present an institutional experience with stent placement in the arterial duct combined with bilateral banding of the pulmonary artery branches as a basis for various surgical strategies in newborns with hypoplastic left heart obstructive lesions. DESIGN: Observational study. SETTING: Paediatric heart centre in a university hospital. PATIENTS: 20 newborns with various forms of left heart obstructive lesions and duct dependent systemic blood flow. INTERVENTIONS: Patients underwent percutaneous ductal stenting and surgical bilateral pulmonary artery banding. Atrial septotomy by balloon dilatation was performed as required, in one premature baby by the transhepatic approach. MAIN OUTCOME MEASURES: Survival; numbers of and reasons for palliative and corrective cardiac surgery. RESULTS: One patient died immediately after percutaneous ductal stenting. One patient died in connection with the surgical approach of bilateral pulmonary banding. Stent and ductal patency were achieved for up to 331 days. Two patients underwent heart transplantation and two patients died on the waiting list. Ten patients had a palliative one stage procedure with reconstruction of the aortic arch and bidirectional cavopulmonary connection at the age of 3.5-6 months. There was one death. One patient is still awaiting this approach. Two patients received biventricular repair. In one, biventricular repair will soon be provided. CONCLUSIONS: Stenting the arterial duct combined with bilateral pulmonary artery banding in newborns with hypoplastic left heart or multiple left heart obstructive lesions allows a broad variation of surgical strategies depending on morphological findings, postnatal clinical conditions, and potential ventricular growth.


Subject(s)
Ductus Arteriosus/surgery , Hypoplastic Left Heart Syndrome/surgery , Pulmonary Artery/abnormalities , Stents , Cardiac Catheterization/methods , Cardiac Output, Low/etiology , Cardiopulmonary Resuscitation , Humans , Infant , Infant, Newborn , Palliative Care , Plastic Surgery Procedures/methods , Survival Analysis
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