Recurrented bilateral low-dose regional anesthesia under ultrasound guidance rather than general anesthesia in a high-risk patient: Rare a case.

Regional anesthesia practices are important because they have the advantages, for example, the patient's awareness is open, spontaneous breathing continues, airway reflexes are preserved, analgesia continues in the post-operative period, and the patient has early mobilization. Local anesthetic at high doses and volumes are used in brachial plexus blocks with nerve stimulator. However, due to the development in ultrasound (US) technology and the increase in image quality, reduced dose of limited anesthesia, and because of its advantages such as vascular and reduced risk of pleural puncture, it has become increasingly widespread. Through US, it is possible to monitor the nerves and anatomical structures, to follow the needle, and to reduce the dose by monitoring the distribution of the local anesthetic given. Organ and tissue losses and tissue infections due to multiple exothermic burns, especially after burns, require multiple surgical procedures. While taking these patients to surgery, anesthesiologists may have difficulty in many stages. For this purpose, they prefer regional anesthesia for less complications. In our study, we aimed to present a low-dose bilateral supraclavicular, infraclavicular, and axillary block with US-guided paraplegic high-risk trauma in a patient with bilateral wounds, forearms, wrists, and wounds caused by burns.

Indicators that determine disease course in COVID-19 patients.

BACKGROUND: In this study, it was tried to determine the factors affecting the clinical process in patients who were followed up in hospital for coronavirus disease-2019 (COVID-19). METHODS: The study, which was designed as a single-center and retrospective cohort, included 658 patients admitted to the service due to COVID-19. The patients were grouped and compared as the patients followed up in the wards (Group 1) and those admitted to ICU (Group 2), between those who were intubated (Group I) in the ICU and those who were not (Group NI), and between patient groups who died (Group M) and survived (Group NM) among those who were intubated. RESULTS: Of the 658 patients hospitalized in the wards, 566 (86%) were discharged and 99 (14%) were later admitted to the ICU. The mortality rate for the 658 patients that were followed up was found to be 7.75%. When Groups 1 and 2 were compared, it was observed that the patients in Group 2 had more comorbidity and higher KDIGO stages (p<0.001). In addition, patients in Group 2 had older age, higher APACHE II and SOFA scores, high WBC counts, neutrophil counts, lymphocyte counts, N/L ratio, CRP, LDH, CK, PTZ, D-dimer, procalcitonin, and ferritin values (all values p<0.001, for CK p=0.034). When the patients in Group I and Group NI were compared, it was observed that the patients in Group I had more comorbidities and higher mortality rate (p<0.001). In addition, patients in Group I had older age, high D-dimer, and ferritin levels (p=0.008; 0.011, and 0.043, respectively). When the patients in Group M and Group NM were compared, it was observed that the patients in Group M were mostly males (p=0.017) and were mostly in KDIGO Stages 1 and 2 (p=0.005). In addition, it was found that the CRP and LDH levels of patients in Group M were significantly higher than those in Group NM (p=0.018 and 0.023, respectively). CONCLUSION: Comorbidity, clinical features, and laboratory findings are parameters that can help in predicting the clinical course of hospitalized patients due to COVID-19.