A Rare Case of Anti-Mi-2 Antibody-Positive Dermatomyositis Associated With Gastrointestinal Stromal Tumor.

Dermatomyositis (DM) with myositis-specific autoantibodies (MSAs) such as anti-Mi-2 antibody confers a negative risk for malignancy.1 A diagnosis of DM carries a 24% risk of developing a malignancy.2.

From Studio to Rehab: A Debilitating Form of Anti-HMGCR Myopathy.

Immune-mediated necrotizing myopathy is a subtype of immune-mediated myopathy associated with or without statin use. Statins, or HMG-CoA reductase inhibitors, are the most prescribed medications for dyslipidemia. The statin-associated myopathic syndromes range from asymptomatic elevations in creatine kinase to severe debilitating muscle weakness with associated rhabdomyolysis and elevated liver enzymes. Clinical improvement occurs upon discontinuation of statins, but some patients do not recover completely. Diagnostic tests include electromyography, muscle biopsy, myositis autoantibody panel, and antibodies against the HMGCR. Here, we present a case of anti-HMGCR-related myopathy associated with atorvastatin.

Acute Hepatitis E Infection Associated With Deer Meat in the United States.

Acute hepatitis E virus (HEV) infection in the United States of America (U.S.A) is low. However, seroprevalence rate is about of 6%. Most cases of HEV infection have been reported from travelers from endemic countries with poor sanitary conditions. Evidence of HEV as a zoonotic infection has been reported from developed countries from swine and wild animals including boar and deer. There is no reported case of direct transmission from wild game to humans in the U.S.A. We report a case of HEV from butchering of deer meat.

Food Stuck in the Throat in a Newly Diagnosed Diabetes Mellitus Patient: An Atypical Presentation of Wallenberg's Syndrome.

Wallenberg's syndrome, also known as posterior inferior cerebellar artery syndrome (lateral medullary syndrome), is known to be a common cause of posterior ischemic stroke syndromes in men in their 60s and may present with varied symptoms devoid of focal neurological signs making it easily missed as a differential of posterior ischemic strokes. It involves a stroke in the vertebral or posterior inferior cerebellar artery of the brainstem. In this case report, we critically examine the case of a 66-year-old man with newly diagnosed diabetes whose main presentation was dysphagia and unsteady gait. There was no motor or sensory examination finding in our patient, and the initial computed tomography of the brain was negative for any intracranial pathology leading to very low suspicion of stroke. However, given a high index of suspicion and a thorough oropharyngeal examination ruling out structural abnormality, magnetic resonance imaging of the brain revealed features suggestive of Wallenberg's syndrome. This case emphasizes careful consideration of posterior stroke syndrome when evaluating patients presenting with dysphagia without typical motor/sensory symptoms of cerebrovascular accident and the requirement of further imaging to support the diagnosis.