ABSTRACT
Denture-induced stomatitis usually occurs in persons who wear a complete or a partial denture. Among the many aetiological and predisposing factors, Candida spp. are believed to play an important role in the initiation and progression of the infection. Seventy cases who attended the clinics of the Dental Faculty, University of Atatürk, Turkey were investigated from the viewpoint of denture-induced stomatitis. After questioning the patients for their personal information, they were examined clinically and smears were obtained from lesions of the palatal mucosa and the contiguous denture surface by calcium aliginate swabs, and inoculated onto Sabouraud dextrose agar supplemented with 1% chloramphenicol, and CHROMagar Candida. Individual yeast species were identified by a germ tube test, development of blastospores, chlamydospores and pseudohyphae and assimilation tests employing the commercial kit API 20C AUX system. According to the results obtained, 70% of the cases had denture-induced stomatitis, and in 68% of them mycological culture results were positive. Candida albicans was the most frequently isolated fungus (68.75%). On the other hand, fungal growth was much more pronounced in the cultures made from the inner surface of the dentures. In conclusion, this study showed that candidal infections are not the predisposing factor in the occurrence of denture-induced stomatitis, but they play a major role, as also some other factors, especially those related with dentures.
Subject(s)
Denture, Complete/microbiology , Fungi/isolation & purification , Stomatitis, Denture/diagnosis , Stomatitis, Denture/microbiology , Adult , Aged , Aged, 80 and over , Diagnosis, Differential , Female , Humans , Male , Middle AgedABSTRACT
OBJECTIVES: Otological solutions have long been used in the treatment of the bacterial and fungal infections of the ear. We investigated antibacterial activity of some otic solutions against the most common bacteria isolated from discharging ears. STUDY DESIGN: Three solutions were used (Castellani's, Burrow's, and 2% salicyl alcohol) for 20 fresh isolates of each of the following organisms: Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa, Escherichia coli, and Enterobacter spp.. The activity of each solution was determined by the size of the zone of inhibition of bacterial growth. RESULTS: The Castellani's solution showed significantly larger average inhibition zones than the other solutions did (p<0.001). CONCLUSION: The Castellani's solution may be considered a good option against bacterial or mixed infections (bacterial and fungal) of the ear.
Subject(s)
Anti-Bacterial Agents/pharmacology , Gram-Negative Bacteria/drug effects , Gram-Positive Bacteria/drug effects , Otitis Media, Suppurative/drug therapy , Administration, Topical , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Humans , Microbial Sensitivity Tests , Otitis Media, Suppurative/microbiologyABSTRACT
The purpose of this study was to determine the erythromycin resistance of group A beta-hemolytic streptococci (GABHS) isolated from throat cultures. GABHS were isolated from 74 (10.4%) throat cultures of 710 patients with upper respiratory tract infections. Penicillin resistance was observed in none of the strains. Of these strains, 4 (5.4%) were found to be resistant to erythromycin. It was concluded that erythromycin resistance in GABHS, although high in some countries, was not a problem in our country at the moment. So, penicillin G and its alternative erythromycin and other macrolides are still reliable antibiotics for the treatment of GABHS infections.
