ABSTRACT
A case of metastatic bronchogenic carcinoma to the gingiva in a 47-year-old male is reported. The gingival lesion developed as a quickly growing mass and appeared 2 months after surgical excision and radiotherapy of the lung carcinoma were completed. The gingival tumor was histopathologically diagnosed as a poorly differentiated squamous carcinoma. Comparative cytologic studies showed similarities between the gingival metastasis and the previous lung cancer.
Subject(s)
Carcinoma, Bronchogenic/pathology , Carcinoma, Bronchogenic/secondary , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/secondary , Gingival Neoplasms/secondary , Lung Neoplasms/pathology , Antigens, Neoplasm/analysis , Gingival Neoplasms/pathology , Humans , Keratins/analysis , Male , Middle Aged , Mitosis , Mucin-1/analysis , Neoplasm Proteins/analysisABSTRACT
A cementifying fibroma associated with a large intraosseous periodontal defect is reported. This tumor was located in the lingual aspect of the first lower left molar. Therapy consisted on flap surgery, tumor excision, and placement of a bone autograft in order to fill the residual bone defect. Six months after the treatment, clinical and radiographic signs of periodontal regeneration were evidenced.
Subject(s)
Mandibular Neoplasms/complications , Odontogenic Tumors/complications , Periodontal Pocket/etiology , Adult , Bone Transplantation , Female , Humans , Mandibular Neoplasms/surgery , Odontogenic Tumors/surgery , Periodontal Pocket/surgeryABSTRACT
This investigation is the result of a multicenter research project between the Catholic University of Leuven and the University of Madrid with the purpose of studying histometrically and ultrastructurally periimplant marginal tissue reactions in mendium-term Brånemark implants. 12 patients were selected and distributed according to predefined clinical and radiological parameters into a periimplant infection group (A) and a non-periimplant infection group (B). Biopsies were taken from these patients and analyzed by means of microscopy (LM), histometry (HM) and transmission electron microscopy (TEM). With LM group A showed pathological features consistent with an advanced gingivitis lesion, while group B showed signs of healthy gingiva in the connective tissue and vauolae formation in the epithelium. With HM, group A showed significantly higher transmigration of inflammatory cells in the epithelium than group B. In the connective tissue, group A showed a higher % of inflammatory infiltrate with significantly higher numbers of plasma cells and mononuclear cells than group B. With TEM, group A showed an ultrastructural picture consistent with plaque-induced periodontitis, while group B showed a rather healthy connective tissue and vacuolae formation in the epithelium. These results suggest that supracrestal marginal tissues around osseointegrated implants react to plaque bacteria similarly to periodontal tissues around teeth by chronic inflammation.
