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1.
Br J Ophthalmol ; 93(5): 569-72, 2009 May.
Article in English | MEDLINE | ID: mdl-19074918

ABSTRACT

BACKGROUND/AIMS: This is a retrospective cohort uveitis survey to determine the clinical features of uveitis in children and assess the rate of complications at two referral centres in Saudi Arabia. METHODS: All children under the age of 16 years presenting with uveitis for the first time between 1997 and 2007 to The Eye Center and King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia were included. Clinical features of uveitis entities were described. Last follow-up visual acuity and ocular complications were analysed. RESULTS: A total of 163 cases of uveitis in children were included. The age range was 1-16 years with a mean age of 10 years. The most frequent clinical type of uveitis in children included acute anterior non-granulomatous uveitis 26%, intermediate uveitis 20%, Vogt-Koyanagi-Harada (VKH) disease 16% and juvenile idiopathic arthritis (JIA) 15%. Anterior uveitis accounted for 42%, intermediate for 20%, posterior for 7%, and panuveitis for 31%. Immune-mediated uveitis was present in 144 (88%) patients, while infectious causes manifested in 19 (12%) patients. CONCLUSIONS: The most common cause of uveitis in children was anterior non-granulomatous uveitis of undetermined aetiology. There was a high prevalence of intermediate uveitis, VKH and JIA. Infectious causes of uveitis were uncommon.


Subject(s)
Uveitis/diagnosis , Adolescent , Child , Child, Preschool , Female , Health Surveys , Humans , Infant , Male , Ophthalmologic Surgical Procedures , Retrospective Studies , Saudi Arabia/epidemiology , Uveitis/epidemiology , Uveitis/etiology , Vision Disorders/epidemiology , Vision Disorders/microbiology , Visual Acuity
2.
Eur J Ophthalmol ; 17(2): 262-5, 2007.
Article in English | MEDLINE | ID: mdl-17415702

ABSTRACT

PURPOSE: To describe development of early choroidal neovascular membrane (CNVM) after laser-assisted in situ keratomileusis (LASIK) procedure in a young myopic patient that was successfully managed by photodynamic therapy (PDT). METHODS: A retrospective interventional case report. RESULTS: A 20-year-old woman with myopic astigmatism underwent uneventful LASIK surgery resulting in best-corrected visual acuity (BCVA) of 20/20 bilaterally. One week later, the patient presented with decreased VA in the right eye and was found to have clinical evidence of central serous chorioretinopathy (CSC). She was treated with systemic corticosteroids without any improvement. Two weeks after LASIK, the patient's VA was 20/200 and clinical evidence of early CNVM was confirmed by fluorescein angiography, indocyanine green angiography, and optical coherence tomography (OCT). PDT resulted in the regression of her CNVM with improvement in her VA and OCT findings. CONCLUSIONS: Systemic corticosteroids may enhance CNVM in patients with LASIK-induced early CNVM. PDT may be effective in the resolution of LASIK-induced CNVM.


Subject(s)
Astigmatism/surgery , Choroidal Neovascularization/etiology , Keratomileusis, Laser In Situ , Myopia/surgery , Postoperative Complications , Adult , Choroidal Neovascularization/diagnosis , Choroidal Neovascularization/drug therapy , Coloring Agents , Female , Fluorescein Angiography , Humans , Indocyanine Green , Photochemotherapy , Photosensitizing Agents/therapeutic use , Retrospective Studies , Tomography, Optical Coherence , Visual Acuity
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