Johanson-Blizzard syndrome caused by novel UBR1 mutation in four Saudi patients.

Johanson-Blizzard syndrome (JBS) is a rare genetic disorder caused by Ubiquitin Protein Ligase E3 Component N-Recognin1 (UBR1) gene mutations. It is characterized by exocrine pancreatic insufficiency, craniofacial deformities, sensorineural hearing loss, and a broad variety of intellectual disabilities. The aim of our study is to report four pediatric cases (three of which are siblings, and the fourth patient is unrelated) that presented some features of JBS. The cases have been confirmed by genetic testing to have mutations in the UBR1 gene. This case series study was conducted retrospectively, giving a detailed description of the demographic and clinical information of these four cases, and reflecting our experience with this subset of patients. All these cases have been treated at the King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia, and were identified by their clinical and laboratory markers that favor JBS. A novel homozygous missense mutation c.2075 T > C (p. lle692Thr) in exon 18 (UBR1: NM_174916.3) was identified and confirmed by Sanger sequencing in all our cases outlined in this paper. These presented cases illustrate the phenotypic variability and complexity of JBS and the importance of physical examination to reach a diagnosis. The identified novel mutation in this study broadens the spectrum of UBR1 mutations that contribute to JBS.

Defects in lead halide perovskite light-emitting diodes under electric field: from behavior to passivation strategies.

Lead halide perovskites (LHPs) are emerging semiconductor materials for light-emitting diodes (LEDs) owing to their unique structure and superior optoelectronic properties. However, defects that initiate degradation of LHPs through external stimuli and prompt internal ion migration at the interfaces remain a significant challenge. The electric field (EF), which is a fundamental driving force in LED operation, complicates the role of these defects in the physical and chemical properties of LHPs. A deeper understanding of EF-induced defect behavior is crucial for optimizing the LED performance. In this review, the origins and characterization of defects are explored, indicating the influence of EF-induced defect dynamics on LED performance and stability. A comprehensive overview of recent defect passivation approaches for LHP bulk films and nanocrystals (NCs) is also provided. Given the ubiquity of EF, a summary of the EF-induced defect behavior can enhance the performance of perovskite LEDs and related optoelectronic devices.

Towards a promising systematic approach to the synthesis of CZTS solar cells.

This study aims to enhance the CZTS device's overall efficiency, the key research area has been identified in this study is to explore the effects of a novel, low-cost, and simplified, deposition method to improve the optoelectronic properties of the buffer layer in the fabrication of CZTS thin film solar cells. Herein, an effective way of addressing this challenge is through adjusting the absorbers' structure by the concept of doping, sensitized CdS thin film by the bi-functional linker, and an environmentally friendly catalytic green agent. The Linker Assisted and Chemical Bath Deposition (LA-CBD) method was introduced as an innovative and effective hybrid sensitization approach. In the one-step synthesis process, Salvia dye, Ag, and 3-Mercaptopropionic acid (MPA) were used. Generally, the results for all samples displayed varying bandgap as achieved between (2.21-2.46) eV, hexagonal structure with considerably decreased strain level, broader grain size, and dramatically enhanced crystalline property. Hence, the rudimentary CdS/CZTS solar cell devices were fabricated for the application of these novel CdS films. Preliminary CZTS thin film solar cell fabrication results in the highest conversion efficiency of 0.266% obtained CdS + Salvia dye, indicating the potential use of the CdS films as a buffer layer for CZTS photovoltaic devices.

Giant condyloma acuminatum surgical management: a case report and literature review.

Introduction and importance: Condyloma acuminatum (CA) or genital warts, represents a rare sexually transmitted disease caused by the human papillomavirus. Infection occurs when host basal cells are exposed to viral infection through a damaged epithelial barrier, during sexual intercourse, or due to other minor skin abrasions. Giant condyloma acuminatum (GCA) has a higher rate of malignant transformation than CA. Case presentation: We are presenting a 44-year-old single gentleman known as a smoker, hepatitis B positive, vitiligo, and hypercholesteromia. He was an alcoholic and had multiple heterosexual relationships abroad. Referred from the dermatology clinic, complaining of genital warts that had increased in size for 10 years. Clinical discussion: CA management includes local applications like imiquimod and podophyllotoxin and clinician-administered treatments such as cryotherapy, surgical excision, electrosurgery, and CO2 laser therapy. Other options, such as interferon, radiotherapy, or chemotherapy, are available. The selection of therapy should be individualized and based upon consideration of the extent of the disease, patient preference, cost, adverse effects, treatment availability, and the response to previous treatments. Complete surgical excision is the treatment of choice for GCA. Conclusion: We present a patient with GCA in the perianal area that was surgically treated with an excellent outcome.

Machine learning models for efficient characterization of Schottky barrier photodiode internal parameters.

We propose ANN-based models to analyze and extract the internal parameters of a Schottky photodiode (SPD) without presenting them with any knowledge of the highly nonlinear thermionic emission (TE) expression of the device current. We train, evaluate and demonstrate the ML models on thirty-six private datasets from three previously published devices, which denote current responses under illumination and ambient temperature of graphene oxide (GO) doped p-Si Schottky barrier diodes (SBDs). The GO doping levels are 0%, 1%, 3%, 5%, and 10%. The illumination ranged from dark (0 mW/cm2) to 30 mW/cm2. The predictions are then made completely at the intensity of 60 mW/cm2. For each diode, some values of the barrier height ([Formula: see text]), ideality factor (n), and series resistance ([Formula: see text]) independently calculated using the Cheung-Cheung method were included in the training dataset. The predictions are done at unspecified intensities on the model development data at 80 and 100 mW/cm2, and on external data at 5% and 20% GO doping which were not part of the development dataset. The ANN achieved a mean square error and mean absolute error score below 0.003 across all datasets. This demonstrates the effective learning capabilities of the ANN models in accurately capturing the photo responses of the photodiodes and accurately predicting the internal parameters of the Schottky Barrier Diodes (SBDs), all without relying on an inherent understanding of the thermionic emission (TE) equation for SBDs. The ANN models achieved high accuracy in this process. The proposed ML models can significantly reduce analysis time in device development cycles and can be applied to other datasets in various fields.

Direct Observation of Photon Induced Giant Band Renormalization in 2D PdSe2 Dichalcogenide by Transient Absorption Spectroscopy.

Insight into fundamental light-matter interaction as well as underlying photo-physical processes is crucial for the development of novel optoelectronic devices. Palladium diselenide (PdSe2 ), an important representative of emerging 2D noble metal dichalcogenides, has gain considerable attention owing to its unique optical, physical, and chemical properties. In this study, 2D PdSe2 nanosheets (NSs) are prepared using the liquid-phase exfoliation method. A broadband carrier relaxation dynamics from visible to near-infrared bands are revealed using a time-resolved transient absorption spectrometer, giving results that indicate band filling and bandgap renormalization (BGR) effects in the 2D PdSe2 NSs. The observed blue-shift of the transient absorption spectra at the primary stage and the subsequent red-shift can be ascribed to this BGR effect. These findings reveal the many-body character of the 2D TMDs material and may hold keys for applications in the field of optoelectronics and ultrafast photonics.

Bias and illumination-dependent room temperature negative differential conductance in Ni-doped ZnO/p-Si Schottky photodiodes for quantum optics applications.

In this article, evidence for the existence of illumination and bias-dependent negative differential conductance (NDC) in Ni-doped Al/ZnO/p-Si Schottky diodes, and the possible mechanism for its origin, are presented. The atomic percentages of Ni doping were 0%, 3%, 5%, and 10%. NDC is observed between -1.5 V to -0.5 V in reverse bias under illumination, but only at certain doping levels and specific forward bias. Furthermore, the devices show excellent optoelectronic characteristics in the photoconductive and photovoltaic modes, with device open circuit voltages ranging from 0.03 V to 0.6 V under illumination.

Toxoplasma and Toxocara seropositivity in juvenile idiopathic arthritis and its relation to disease activity and type of therapies.

Juvenile idiopathic arthritis (JIA) is the most frequently encountered autoimmune rheumatic disease in children. To our knowledge, this is the first study aimed to estimate the frequency of Toxoplasma gondii (T. gondii) and Toxocara seropositivity in JIA and assess its relation to the disease activity, IL-10 levels, and type of the received therapies. This study was conducted on 43 JIA patients and 50 cases as a control group. All participants were evaluated by disease activity score (JADAS-27), and the presence of specific IgG and IgM antibodies against T. gondii and IgG against Toxocara species using an enzyme-linked immunosorbent assay. IL-10 serum levels were measured using an ELISA kit. The results show that JIA patients have significantly higher seropositivity for anti-T. gondii IgG compared to control subjects (p = 0.02) and a non-significant difference for Toxocara seropositivity (p = 0.41). All participants were negative for IgM anti-Toxoplasma gondii. Demographic parameters did not significantly affect these seroprevalence frequencies (p > 0.05). IL-10 was significantly higher among JIA patients compared to controls (p = 0.007) and seropositive anti-T. gondii JIA exhibited significantly higher IL-10 levels compared to seronegative ones (p = 0.03). Seropositive anti-T. gondii IgG JIA patients had a significantly higher disease activity score (JADAS-27) than seronegative anti-T. gondii IgG cases (p = 0.02). There was a significant positive correlation between anti-T. gondii IgG and JADAS-27 score (p = 0.009). A significant association was detected between T. gondii infection and DMARDs including the biological therapies (p < 0.05). Overall, this study supports a possible association between T. gondii infection and JIA, IL-10, disease activity score, and DMARDs therapies. It is possible that IL-10 plays a role in the development of JIA and contributes to persistent asymptomatic infection with T. gondii in JIA patients. As a result, a recommendation for screening tests for T. gondii infection among JIA patients is crucial before and during commencing DMARDs therapies and closely monitoring early signs of infection.

A Flexible Miniature Antenna for Body-Worn Devices: Design and Transmission Performance.

The last few years have seen a rapid increase in body-worn devices because these devices cover a broad spectrum of potential uses. Moreover, body-worn devices still require improvements in their flexibility, size, and weight that necessitate the development of flexible and miniature antennas. In this paper, we present a new flexible miniature antenna for body-worn devices. To ensure flexibility and comfort when the antenna is in contact with the human body, a substrate from natural rubber filled with TiO2 is developed. The miniaturization is achieved using the quadratic Koch curve. The antenna design, optimization, and characterization are performed on a human body model. The performance of the antenna is analyzed in two scenarios: (1) in- to on-body, and (2) on- to off-body wireless communications. The results show that the antenna realized the maximum telemetry range of more than 80 mm for in-body communications and more than 2 m for off-body communications. Moreover, the highest 10 g specific absorption rate value was 0.62 W/kg. These results, in addition to the antenna's compact dimensions (12 mm × 26 mm × 2.5 mm) and the low manufacturing price, make the proposed antenna an ideal candidate for health telemetry applications.

Superparamagnetic Multifunctionalized Chitosan Nanohybrids for Efficient Copper Adsorption: Comparative Performance, Stability, and Mechanism Insights.

To limit the dangers posed by Cu(II) pollution, chitosan-nanohybrid derivatives were developed for selective and rapid copper adsorption. A magnetic chitosan nanohybrid (r-MCS) was obtained via the co-precipitation nucleation of ferroferric oxide (Fe3O4) co-stabilized within chitosan, followed by further multifunctionalization with amine (diethylenetriamine) and amino acid moieties (alanine, cysteine, and serine types) to give the TA-type, A-type, C-type, and S-type, respectively. The physiochemical characteristics of the as-prepared adsorbents were thoroughly elucidated. The superparamagnetic Fe3O4 nanoparticles were mono-dispersed spherical shapes with typical sizes (~8.5-14.7 nm). The adsorption properties toward Cu(II) were compared, and the interaction behaviors were explained with XPS and FTIR analysis. The saturation adsorption capacities (in mmol.Cu.g-1) have the following order: TA-type (3.29) > C-type (1.92) > S-type (1.75) > A-type(1.70) > r-MCS (0.99) at optimal pH0 5.0. The adsorption was endothermic with fast kinetics (except TA-type was exothermic). Langmuir and pseudo-second-order equations fit well with the experimental data. The nanohybrids exhibit selective adsorption for Cu(II) from multicomponent solutions. These adsorbents show high durability over multiple cycles with desorption efficiency > 93% over six cycles using acidified thiourea. Ultimately, QSAR tools (quantitative structure-activity relationships) were employed to examine the relationship between essential metal properties and adsorbent sensitivities. Moreover, the adsorption process was described quantitatively, using a novel three-dimensional (3D) nonlinear mathematical model.

Room Temperature Synthesized TiO2 Nanoparticles for Two-Folds Enhanced Mechanical Properties of Unsaturated Polyester.

Using of nano-inclusion to reinforce polymeric materials has emerged as a potential technique to achieve an upper extreme of specific strength. Despite the significant improvement of mechanical properties via nano-reinforcements, the commercial application of such nano-composites is still restricted, due to high cost and unwanted aggregation of nanoparticles in the polymer matrix. To address these issues, here we proposed a scalable and economical synthesis of TiO2 at low temperatures, resulting in self-dispersed nanoparticles, without any surfactant. As lower energy is consumed in the synthesis and processing of such nanoparticles, so their facile gram-scale synthesis is possible. The defect-rich surface of such nanoparticles accommodates excessive dangling bonds, serving as a center for the functional groups on the surface. Functional surface enables high dispersion stability of room temperature synthesized TiO2 particles. With this motivation, we optimized the processing conditions and concentration of as-synthesized nano-particles for better mechanical properties of unsaturated polyester (UP) resin. The composite structure (UP-TiO2) showed nearly two folds higher tensile, flexural, and impact strength, with 4% content of nanoparticles. Characterization tools show that these better mechanical properties are attributed to a strong interface and superior dispersion of nanoparticles, which facilitate better stress distribution in the composite structure. In addition, the crack generation and propagation are restricted at a much smaller scale in nanocomposites, therefore significant improvement in mechanical properties was observed.

Attitude of Self-Medication Among Pharmacy Students in King Abdulaziz University, Jeddah, Saudi Arabia: A Cross-Sectional Survey.

Background/purpose Self-medication is a public health concern because of the potential for medication overuse or abuse, as well as the physical, social, and psychological consequences. In Saudi Arabia, self-medication is common, especially among health science students. Inappropriate self-medication can cause several adverse effects, such as increasing the risk of medication abuse or delaying hospital appointments due to concealing specific symptoms with some medications. Therefore, our study aims to investigate and evaluate health science students' practices, awareness, and attitudes towards self-medication in the Faculty of Pharmacy at King Abdulaziz University, Jeddah, Saudi Arabia. Materials and methods A cross-sectional study was conducted using an online self-administered survey to measure the attitude, awareness, and prevalence of self-medication among pharmacy students at King Abdulaziz University in Jeddah, Saudi Arabia. Students in the pharmacy program from the first to the sixth year were invited to participate in the study from April 2019 to June 2019. Raosoft was used to compute the sample size (n = 235) with a 5% margin of error and a 95% confidence range. Results The factors associated with significant effects were an academic year (p = 0.001), smoking (p = 0.018), average sleeping time (p = 0.032), having any headache (p = 0.022), and their opinion about self-medication (p < 0.0001). Conclusion According to the study, the self-medication of analgesics is common among pharmacy students, and the most used medication was paracetamol.

A Targeted Review of Current Progress, Challenges and Future Perspective of g-C3 N4 based Hybrid Photocatalyst Toward Multidimensional Applications.

The increasing demand for searching highly efficient and robust technologies in the context of sustainable energy production totally rely onto the cost-effective energy efficient production technologies. Solar power technology in this regard will perceived to be extensively employed in a variety of ways in the future ahead, in terms of the combustion of petroleum-based pollutants, CO2 reduction, heterogeneous photocatalysis, as well as the formation of unlimited and sustainable hydrogen gas production. Semiconductor-based photocatalysis is regarded as potentially sustainable solution in this context. g-C3 N4 is classified as non-metallic semiconductor to overcome this energy demand and enviromental challenges, because of its superior electronic configuration, which has a median band energy of around 2.7 eV, strong photocatalytic stability, and higher light performance. The photocatalytic performance of g-C3 N4 is perceived to be inadequate, owing to its small surface area along with high rate of charge recombination. However, various synthetic strategies were applied in order to incorporate g-C3 N4 with different guest materials to increase photocatalytic performance. After these fabrication approaches, the photocatalytic activity was enhanced owing to generation of photoinduced electrons and holes, by improving light absorption ability, and boosting surface area, which provides more space for photocatalytic reaction. In this review, various metals, non-metals, metals oxide, sulfides, and ferrites have been integrated with g-C3 N4 to form mono, bimetallic, heterojunction, Z-scheme, and S-scheme-based materials for boosting performance. Also, different varieties of g-C3 N4 were utilized for different aspects of photocatalytic application i. e., water reduction, water oxidation, CO2 reduction, and photodegradation of dye pollutants, etc. As a consequence, we have assembled a summary of the latest g-C3 N4 based materials, their uses in solar energy adaption, and proper management of the environment. This research will further well explain the detail of the mechanism of all these photocatalytic processes for the next steps, as well as the age number of new insights in order to overcome the current challenges.

A Tunable and Wearable Dual-Band Metamaterial Absorber Based on Polyethylene Terephthalate (PET) Substrate for Sensing Applications.

Advanced wireless communication technology claims miniaturized, reconfigurable, highly efficient, and flexible meta-devices for various applications, including conformal implementation, flexible antennas, wearable sensors, etc. Therefore, bearing these challenges in mind, a dual-band flexible metamaterial absorber (MMA) with frequency-reconfigurable characteristics is developed in this research. The geometry of the proposed MMA comprises a square patch surrounded by a square ring, which is mounted over a copper-backed flexible dielectric substrate. The top surface of the MMA is made of silver nanoparticle ink and a middle polyethylene terephthalate (PET) substrate backed by a copper groundsheet. The proposed MMA shows an absorption rate of above 99% at 24 and 35 GHz. In addition, the absorption features are also studied for different oblique incident angles, and it is found that the proposed MMA remains stable for θ = 10-50°. The frequency tunability characteristics are achieved by stimulating the capacitance of the varactor diode, which connects the inner patch with the outer ring. To justify the robustness and conformability of the presented MMA, the absorption features are also studied by bending the MMA over different radii of an arbitrary cylinder. Moreover, a multiple-reflection interference model is developed to justify the simulated and calculated absorption of the proposed MMA. It is found that the simulated and calculated results are in close agreement with each other. This kind of MMA could be useful for dual-band sensing and filtering operations.

Infrared Light Emission Devices Based on Two-Dimensional Materials.

Two-dimensional (2D) materials have garnered considerable attention due to their advantageous properties, including tunable bandgap, prominent carrier mobility, tunable response and absorption spectral band, and so forth. The above-mentioned properties ensure that 2D materials hold great promise for various high-performance infrared (IR) applications, such as night vision, remote sensing, surveillance, target acquisition, optical communication, etc. Thus, it is of great significance to acquire better insight into IR applications based on 2D materials. In this review, we summarize the recent progress of 2D materials in IR light emission device applications. First, we introduce the background and motivation of the review, then the 2D materials suitable for IR light emission are presented, followed by a comprehensive review of 2D-material-based spontaneous emission and laser applications. Finally, further development directions and challenges are summarized. We believe that milestone investigations of 2D-material-based IR light emission applications will emerge soon, which are beneficial for 2D-material-based nano-device commercialization.

Synergetic effect of bismuth vanadate over copolymerized carbon nitride composites for highly efficient photocatalytic H2 and O2 generation.

The development of copolymerized carbon nitride (CN)-based photocatalysts may support advances in photocatalytic overall water splitting. However, the recombination of charge carriers is the main bottleneck that reduces its overall photocatalytic activity. To overcome this problem, the construction of heterojunction technology has emerged as an effective approach to reduce the charge carrier recombination, thereby improving charge separation and transport efficiency. In this work, an innovative heterojunction was prepared between Quinolinic acid (QA) modified CN (CN-QAx) and novel nanorod-shaped bismuth vanadate (BiVO4) (BiVO4/CN-QAx) for overall water splitting through a simple in-situ solvent evaporation technique. The obtained results show that the synthesized samples have efficient and improved activities for releasing H2 (862.1 µmol/h) and O2 (31.58 µmol/h) under visible light irradiation. Furthermore, an exceptional apparent quantum yield (AQY) of 64.52 % has been recorded for BiVO4/CN-QA7.0 at 420 nm, which might be due to the substantial isolation of photoinducedcharge carriers. Therefore, this work opens up a new channel toward efficient CN-based photocatalysts in the sustainable energy production processes.

Mesoporous Magnetic Cysteine Functionalized Chitosan Nanocomposite for Selective Uranyl Ions Sorption: Experimental, Structural Characterization, and Mechanistic Studies.

Nuclear power facilities are being expanded to satisfy expanding worldwide energy demand. Thus, uranium recovery from secondary resources has become a hot topic in terms of environmental protection and nuclear fuel conservation. Herein, a mesoporous biosorbent of a hybrid magnetic-chitosan nanocomposite functionalized with cysteine (Cys) was synthesized via subsequent heterogeneous nucleation for selectively enhanced uranyl ion (UO22+) sorption. Various analytical tools were used to confirm the mesoporous nanocomposite structural characteristics and confirm the synthetic route. The characteristics of the synthesized nanocomposite were as follows: superparamagnetic with saturation magnetization (MS: 25.81 emu/g), a specific surface area (SBET: 42.56 m2/g) with a unipore mesoporous structure, an amine content of ~2.43 mmol N/g, and a density of ~17.19/nm2. The experimental results showed that the sorption was highly efficient: for the isotherm fitted by the Langmuir equation, the maximum capacity was about 0.575 mmol U/g at pH range 3.5-5.0, and Temperature (25 ± 1 °C); further, there was excellent selectivity for UO22+, likely due to the chemical valent difference. The sorption process was fast (~50 min), simulated with the pseudo-second-order equation, and the sorption half-time (t1/2) was 3.86 min. The sophisticated spectroscopic studies (FTIR and XPS) revealed that the sorption mechanism was linked to complexation and ion exchange by interaction with S/N/O multiple functional groups. The sorption was exothermic, spontaneous, and governed by entropy change. Desorption and regeneration were carried out using an acidified urea solution (0.25 M) that was recycled for a minimum of six cycles, resulting in a sorption and desorption efficiency of over 91%. The as-synthesized nanocomposite's high stability, durability, and chemical resistivity were confirmed over multiple cycles using FTIR and leachability. Finally, the sorbent was efficiently tested for selective uranium sorption from multicomponent acidic simulated nuclear solution. Owing to such excellent performance, the Cys nanocomposite is greatly promising in the uranium recovery field.

Evaluation of the Synergistic Effect of Graphene Oxide Sheets and Co3O4 Wrapped with Vertically Aligned Arrays of Poly (Aniline-Co-Melamine) Nanofibers for Energy Storage Applications.

In the present study, Co3O4 and graphene oxide (GO) are used as reinforcement materials in a copolymer matrix of poly(aniline-co-melamine) to synthesize ternary composites. The nanocomposite was prepared by oxidative in-situ polymerization and used as an electrode material for energy storage. The SEM images revealed the vertically aligned arrays of copolymer nanofibers, which entirely wrapped the GO sheets and Co3O4 nanoparticles. The EDX and mapping analysis confirmed the elemental composition and uniform distribution in the composite. The XRD patterns unveiled composites' phase purity and crystallinity through characteristic peaks appearing at their respective 2θ values in the XRD spectrum. The FTIR spectrums endorse the successful synthesis of composites, whereas TGA analysis revealed the higher thermal stability of composites. The cyclic voltammetry, galvanostatic charge-discharge, and electrochemical impedance spectroscopy are employed to elucidate the electrochemical features of electrodes. The ternary composite PMCoG-2 displayed the highest specific capacity of 134.36 C/g with 6 phr of GO, whereas PMCoG-1 and PMCoG-3 exhibited the specific capacities of 100.63 and 118.4 C/g having 3 phr and 12 phr GO at a scan rate of 0.003 V/s, respectively. The best electrochemical performance of PMCoG-2 is credited to the synergistic effect of constituents of the composite material.

Mechanistic study of Hg(II) interaction with three different α-aminophosphonate adsorbents: Insights from batch experiments and theoretical calculations.

Herein, efficient and potential chelating α-aminophosphonate based sorbents (AP-) derived from three different amine origins (aniline/anthranilic acid/O-phenylenediamine) to form AP-H, carboxylated and aminated enhanced aminophosphonate as AP-H, AP-COOH, and AP-NH2 were synthesized via a facile method. The structure of the synthesized sorbents was elucidated using different techniques; elemental analysis (CHNP/O), FT-IR, NMR (1H-, 13C and 31P NMR), TGA and BET. The fabricated sorbents were exploited for Hg(II) removal from aqueous solution via sorption properties. Isotherm fitted by Langmuir equation: the maximum sorption capacities at optimum pH 5.5, and T:25 ± 1 °C, were found to be 1.33, 1.23, and 1.15 mmol Hg g-1 for AP-COOH, AP-NH2, AP-H, respectively, which is roughly correlated with the active sites density and the hard/soft characteristics of adsorbents' reactive groups. Metal-ligand binding affinities are qualitatively rationalized in terms of hard and soft acids and bases (HSAB) theory. The interaction of Hg(II) (soft) has a stronger affinity to AP-COOH can be considered a softer base compared with reference material (AP-H) over than AP-NH2 (hard). This sequence result showed opposite trends consistent with their reciprocal properties according to the steric effect modulates and the specific surface area. Thermodynamics analysis for absolute values of ΔH°, ΔS° and ΔG° afford the selectivity towards Hg(II) sorption with the following order: AP-COOH > AP-NH2 >AP-H. Elution and regeneration was carried out by HCl solution and recycled for a minimum of five cycles, the sorption and desorption efficiencies are greater than 91%. Such sorbents exhibit good durability, stability and promising potential for Hg(II) removal. Finally, a new modelling technique for quantitative non-linear description and comparison of equivalent geographical positions in 3D space of extended relationships. Exothermic and spontaneous behavior were observed using a proposed Floatotherm that included the Van't Hoff parameters model.