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BMJ Case Rep ; 20182018 Oct 12.
Article in English | MEDLINE | ID: mdl-30317200

ABSTRACT

A young man previously diagnosed with Kleine-Levin syndrome (KLS) presented with abnormal behaviour over the last 8 days. This included decreased sleeping hours and appetite, hypersexuality, aggressiveness and visual hallucinations. All blood tests and investigations in the emergency department yielded normal results. A preliminary diagnosis of a KLS episode with psychosis was made and the patient was started on a regimen of aripiprazole 10 mg once daily along with lorazepam 2 mg intravenously in two divided doses in the event of agitation or insomnia. On discharge 5 days later, the patient had returned to his premorbid level of functioning and was willing to follow up in the neurology clinic. He was discharged on aripiprazole 10 mg once daily and lorazepam 2 mg two times daily as needed for 2 weeks to help with his agitation and insomnia, as well as lithium carbonate 400 mg at night.


Subject(s)
Kleine-Levin Syndrome/diagnosis , Sleep Initiation and Maintenance Disorders/diagnosis , Adolescent , Antimanic Agents/administration & dosage , Antimanic Agents/therapeutic use , Diagnosis, Differential , Hallucinations/etiology , Humans , Kleine-Levin Syndrome/complications , Kleine-Levin Syndrome/drug therapy , Lithium Carbonate/administration & dosage , Lithium Carbonate/therapeutic use , Male , Sleep Initiation and Maintenance Disorders/complications , Sleep Initiation and Maintenance Disorders/drug therapy
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