Main-Duct Intraductal Papillary Mucinous Neoplasm Complicated by a Pancreaticogastric Fistula and a Pancreaticocholedocal Fistula.

Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are a spectrum of benign to malignant epithelial neoplasms that are characterized by papillary proliferation, duct dilation, and cyst formation. A rare complication of IPMNs is fistula formation into adjacent organs such as the duodenum, biliary system, and stomach. Here, we report a case of IPMN with a pancreaticobiliary fistula and pancreaticogastric fistula. An 84-year-old woman with early Alzheimer's disease was diagnosed with IPMN of the pancreas. She deferred surgery given her age and remained asymptomatic for five years until presenting with cholangitis. She had been further evaluated and was found to have a pancreaticobiliary fistula, which was treated with biliary stent placement. Her subsequent admission involved the formation of a new pancreaticogastric fistula. This case highlights potential complications of excess mucin production from unresected IPMNs and demonstrates a guarded prognosis in elderly patients.

Periampullary Clot Causing Biliary Obstruction: A Rare Presentation.

Acute cholangitis is an emergency condition that requires an emergency biliary drainage for source control of the infection. Commonly cholangitis is precipitated by biliary obstruction due to causes like stones, strictures, stents, or malignancy of the pancreaticobiliary or ampullary origin. We report a unique case of a man who had acute cholangitis due to a periampullary clot who was fully recovered after clot removal by endoscopic retrograde cholangiopancreatography (ERCP).