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Clin Chem ; 29(1): 164-6, 1983 Jan.
Article in English | MEDLINE | ID: mdl-6848256

ABSTRACT

Different indexes of thyroid function were determined in conjunction with values obtained with a new commercial radioimmunoassay kit for serum free thyroxin, in 49 apparently healthy subjects, 87 pregnant women, and 142 outpatients attending the thyroid clinic. The results indicate a diagnostic success rate of 88% when free thyroxin was measured instead of estimating the so-called free thyroxin index. Furthermore, in three cases of papillary carcinoma the concentration of free thyroxin was increased, although all the other laboratory tests indicated a euthyroid state. Technically, the method is simple, rapid, and precise, and it would be of most value in the small hospital laboratory lacking the facilities of a comprehensive thyroid-function test service.


Subject(s)
Thyroid Diseases/blood , Thyroxine/blood , Adolescent , Adult , Aged , Binding Sites , Carcinoma, Papillary/blood , Evaluation Studies as Topic , Female , Humans , Middle Aged , Pregnancy , Radioimmunoassay , Reagent Kits, Diagnostic
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