The use of extracorporeal shock wave therapy (ESWT) in treating osteonecrosis of the femoral head (AVNFH): a retrospective study.

PURPOSE: As most of the cases of avascular necrosis (AVN) in Saudi Arabia is seen in young population and as literature showed good effect of extracorporeal shock wave therapy (ESWT) in reducing pain and oedema in avascular necrosis and delaying the need of surgical intervention. Our purpose of this study is to assess the effectiveness of ESWT in reducing pain, improving range of motion (ROM) and delaying the surgical intervention in patient with AVN of femoral head and compare our results to published literature. MATERIAL AND METHODS: We have treated 24 patients, 13 males and 11 females with a mean age of 29 years (range 14-48) with 34 hips affected. There were 14 unilateral and ten bilateral lesions. In our series 11 out of 24 patients (45.8%) were due to sickle cell disease. Other causes included idiopathic in five patients (20.8%), corticosteroids use and systemic lupus erythematous in three patients each (12.5% each) and post-traumatic AVN in two patients (8.3%). Extracorporeal shock wave therapy was implanted in FICAT stage I, II and III. All patients had two sessions of extracorporeal shock wave therapy, four to six weeks apart, each with 4000 impulses divided into four points. Radiological and MRI assessment were performed at regular time intervals with a minimum follow-up of two years. Clinical assessment was based on Visual Analog Scale and Harris Hip Score (HHS). The end point outcome measurement was the need for any operative intervention. RESULTS: Operative intervention was necessary in eight out of 34 hips (23.5%), within an average of 2.5 years (range 1 to 5 years). A hip salvage was achieved in 76.5%. Function was improved with the Harris Hip Score from a mean of 54.6 to 80.4 (P value using paired t test ≤ 0.05). Pain assessed with Visual Analog Scale improved from 5.73 to 2.75 (P value using paired t test ≤ 0.05). CONCLUSION: We do recommend the use of ESWT in treating AVN of bone whether of femoral head or other sites prior to the collapse of the articular surface. Further studies are needed to compare using two or more sessions as well as using four or six points for ESWT.

Canal of Nuck hernia containing the internal reproductive organs of both gender in a neonate with disorder of sex development: a rare case presentation.

The combination of disorder of sex development and canal of Nuck hernia, in which the hernial sac contains the internal reproductive organs (gonads) of both genders, is exceedingly rare. We present a unique case of a neonate who presented with ambiguous genitalia and a lump in the left inguinal region. The child underwent various radiographic procedures and hernial repair. Blood work-up, karyotyping, and histopathological analysis from gonads confirmed the diagnosis of Ovotesticular disorder of sex development. Subsequently, the child had a reconstructive vaginoplasty, and the final decision regarding gender assignment will be made after assessing mental and sexual behavior in early childhood.

Renal and mediastinal perivascular epithelioid cell tumors (PEComas) in a young child with tuberous sclerosis; a rare case report.

We describe a unique case of perivascular epithelioid cell tumors occurring as mediastinal and left renal soft tissue masses discovered incidentally in a 5-year-old tuberous sclerosis patient upon presentation to the emergency department for upper respiratory illness. The radiographic features were non-specific. However, the similar CT characteristics of both lesions and background history raised the suspicion of a synchronous mesenchymal tumor, and histopathology confirmed the diagnosis. The rarity of these tumors in the pediatric population and lack of specific diagnostic criteria impose reporting the case and emphasize the need for further research on imaging features of such tumors.

Spontaneous Spinal Epidural Hematoma in a 12-Year-Old Child.

Spontaneous spinal epidural hematoma (SSEH) is uncommon, with an estimated incidence of one per million per year in the general population. Since SSEH was first described, only 29 cases have been reported in children. This condition is difficult to diagnose and needs immediate surgical intervention for hematoma evacuation and cord decompression to obtain optimal functional and neurological outcomes. The presentation in children might be atypical. We present a case that was managed surgically and yielded full recovery.

Idiopathic myositis ossificans of the deltoid muscle: A case report with unique presentation and MRI findings.

INTRODUCTION: Myositis ossificans of the deltoid muscle is extremely rare. We present a case with unique presentation and MRI findings. CASE REPORT: A 21-year-old female presented with a 3-month history of a swelling in lateral aspect of the right arm. There was no history of trauma, injection, or surgery to the area. Examination showed a 3 × 3 cm firm mass in the deltoid muscle. MRI findings were suggestive of myxoma. Surgical excision was done and histopathology showed the classic features of myositis ossificans. There was no recurrence at the final follow-up 7 months later. DISCUSSION: Myositis ossificans of the deltoid muscle is very rare with only 6 cases previously reported in the literature. Our case is unique in presentation because it is the first case reported with no history of trauma, Injection, sickness or surgery in the area. We also review the literature for MRI features of Myositis ossificans and show that our case has a unique pattern. CONCLUSION: We report on a rare case of Myositis ossificans of the deltoid muscle and review of the literature for similar cases and MRI features of Myositis ossificans. We show that our case was unique both in presentation and MRI finding.

Outcome of pulmonary embolism and clinico-radiological predictors of mortality: Experience from a university hospital in Saudi Arabia.

OBJECTIVES: The objective of this study is to determine the outcome of pulmonary embolism (PE) and the clinico-radiological predictors of mortality in a university hospital setting. METHODS: A Prospective observational study conducted at King Khalid University Hospital, Riyadh Saudi Arabia between January 2009 and 2012. A total of 105 consecutive patients (49.9 ± 18.7 years) with PE diagnosed by computed tomography pulmonary angiography were followed until death or hospital discharge. RESULTS: Overall in hospital mortality rate was 8.6%, which is lower than other international reports. Two-thirds of patients developed PE during the hospitalization. The most common risk factors were surgery (35.2%), obesity (34.3%) and immobility (30.5%). The localization of the embolus was central in 32.4%, lobar in 19% and distal in 48.6%. A total of 26 patients (25%) had evidence of right ventricular strain and 14 (13.3%) were hypotensive. Multivariate analysis revealed that heart failure (Beta = -0.53, P < 0.001), palpitation (Beta = -0.24, P = 0.014) and high respiratory rate (Beta = -0.211, P < 0.036) were significant predictors of mortality. There was no significant difference in the localization of the embolus or obstruction score between survivors and non-survivors. CONCLUSION: The outcome of PE is improving; however, it remains an important risk factor for mortality in hospitalized patients. Congestive heart failure, tachypnea and tachycardia at presentation were associated with higher mortality. These factors need to be considered for risk stratification and management decisions of PE patients. Radiological quantification of clot burden was not a predictor of death.

Hyperphosphatasemia in an adult. Clinical, conventional roentgenographic, and CT findings.

A 47-year-old Saudi deaf lady with short stature presented being unable to walk. She had long standing diffuse skeletal deformities, and progressive head enlargement. She had markedly elevated serum alkaline phosphatase. The radiographic changes were those of hyperphosphatasemia, and the CT scanning of the skull, which was not studied before, further elicited the extensive calvarial and basilar changes. The various entities of hyperphosphatasemia with and without bony changes are reviewed.

Prediction of pulmonary hypertension in patients with or without interstitial lung disease: reliability of CT findings.

PURPOSE: To study the reliability of pulmonary vascular measurements based on computed tomography (CT) in the prediction of pulmonary hypertension (PH) in patients with advanced interstitial lung disease (ILD) compared with those without ILD. MATERIALS AND METHODS: The study was approved by the Institutional Review Board. All patients gave written informed consent. A prospective study of 134 patients who underwent right-sided heart catheterization and chest CT scanning within 72 hours of admission was conducted. Patients were divided into two groups-one with ILD (group A, n = 100) and one without ILD (group B, n = 34). CT measurements of the main pulmonary artery diameter (PAD), the ratio of PAD to the ascending aorta diameter (AAD), right pulmonary artery diameter (RPAD), and left pulmonary artery diameter (LPAD) were obtained. Univariate logistic regression analysis was performed, and receiver operating characteristic curves were constructed to assess the predictive ability of vascular measurements obtained by using CT in the identification of PH. RESULTS: Main PAD was significantly greater in patients with PH than in those without PH in both groups (group A, P = .008; group B, P = .02). A PAD greater than 25 mm in patients with ILD was predictive of PH, with a sensitivity of 86.4% (32 of 37), a specificity of 41.2% (26 of 63), a positive predictive value of 46.3% (32 of 69), and a negative predictive value of 83.8% (26 of 31). In patients without ILD, a PAD greater than 31.6 mm and an LPAD greater than 21.4 mm were predictive of PH (sensitivity, 47.3% [nine of 19]; specificity, 93.3% [14 of 15]; positive predictive value, 90.0% [nine of 10]; and negative predictive value, 58.3% [14 of 24]). CONCLUSION: CT-derived vascular measurements were of limited utility in the prediction of PH in patients with ILD compared with those without ILD.

Bilateral intraductal papillomas arising in ectopic axillary breast tissue synchronously with right breast intraductal carcinoma.

This study describes a case of 45-year-old woman with a mass developed in the right breast. Physical examination revealed a 3 cm painless mass in the right breast as well as diffuse bulge in both axillary regions, though no significant lymphadenopathy was evident. Mammogram and ultrasound examination were carried out and showed malignant mass in the right breast and ectopic breast tissue in both axillae with multiple intraductal papillomas. Both mammographic and sonographic appearances of these lesions are described and discussed. The purpose of this study is to highlight the importance of occurrence of bilateral ectopic axillary breast with intraductal papilloma synchronously with right breast malignant mass and emphasize the importance of thorough mammographic and sonographic examination of the axilla in detecting such pathology.

Magnetic resonance imaging evaluation of temporomandibular joint derangement in symptomatic and asymptomatic patients.

OBJECTIVE: To highlight the importance of MRI in evaluation of the tempromandibular joint (TMJ). METHODS: The MRI examination was performed at King Khalid University Hospital, Riyadh, Saudi Arabia with the approval from the local ethics committee, on 34 patients (68 joints) between January 2006 and November 2007, in which 10 were considered asymptomatic subjects (control). The remaining had symptoms and signs of TMJ pain or dysfunction, including limitation of movement and clicking. All our subjects were examined in both closed and open mouth position. Images were obtained by 1.5-T MRI system, in oblique sagittal plane utilizing 3 pulse sequences including T1 and T2 spin-echo, and spoiled gradient recall sequences. The evaluation of the meniscal disc configuration and position was carried out by 2 radiologists. RESULTS: Sixteen out of 20 joints of asymptomatic subjects were normal. In the other 2 asymptomatic subjects, the MRI showed anterior disc displacement with reduction in 3 joints, and degenerative changes in 2 joints. Out of the 48 symptomatic joints, 26 (45%) joints were considered normal, while the other 22 joints showed anterior dislocation without reduction. Degenerative joint disease was also seen in 18 joints. CONCLUSION: The MRI with the use of surface coils markedly improves the delineation of internal derangement of the TMJ, therefore, it enhanced the capability of detecting certain abnormalities, which proved to have a statistical significance in symptomatic patients.

The utility of unenhanced helical CT in assessing the frequency of ureterolithiasis in Saudi patients.

OBJECTIVE: To identify 650 patients who underwent CT for renal colic, and review them for age and gender, in Saudi Arabia. METHODS: Scans were performed on a 16 multislice scanner. A total of 650 patients, with the clinical suspicion of ureteric colic were reviewed; 220 females (33.8%) and 430 males (66.2%), with a female to male ratio of 1:2. Exams were carried out from January 2005 to November 2006, at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia. RESULTS: Three hundred and ninety five patients out of 650 had stones; 2 of 395 (0.5%) had stones in the 5-15 years age group, 28 (7.1%) in the 16-25 years age group, 99 (25.1%) in the 26-35 years, 106 (26.8%) in the 36-45 age group, 84 (21.9%) in the 46-55 age group, 51 (12.9%) in the 56-65 age group, and 25 (6.3%) in the above 66 years age group. The most significant finding in our study is that as the patients age increases so does the percentage of stones up to the age of 56, with a peak at age group of 26-35 where stone percentage reaches 26.8%. CONCLUSION: Unenhanced helical CT is useful for the diagnosis of ureterolithiasis.

Patterns of radiographic changes in hands and feet of rheumatoid arthritis in Saudi Arabia.

OBJECTIVE: The aim of the study was to characterize the pattern of radiographic changes in the hands and feet of rheumatoid arthritis in Saudi patients. METHODS: The radiographs of hands and feet of rheumatoid arthritis patients attending rheumatology outpatient clinics of King Khalid University Hospital in Riyadh, Kingdom of Saudi Arabia, over the period extending from March to June 2001, were examined and reported for the presence of osteopenia, joint space narrowing, and erosions. RESULTS: Fifty-six rheumatoid arthritis patients were studied. Their mean age was 50 + 1.9 years, and mean disease duration was 9.07 + 0.84 years. Generalized osteopenia was seen in 16/56 (29%) and periarticular osteopenia in 38/56 (68%). Joint space narrowing was present in 9/56 (16%) of feet and 35/56 (63%) of hand x-rays. Erosions were seen in 3/56 (6%) of feet and in 22/56 (39%) of hand x-rays. Significant correlation was seen between joints space narrowing, joint erosions, and disease duration. CONCLUSION: Radiographic changes in hands and feet of Saudi rheumatoid arthritis patients are less severe than those reported from the West, and the pattern is also different with less affection of the feet.

Acute retropharyngeal and parapharyngeal abscesses in children.

OBJECTIVE: Acute retropharyngeal and parapharyngeal abscess is a rare but serious disease in children. We reviewed our experience highlighting some of the unusual features of our cases. METHODS: Medical records of children less than 12-years-old who were admitted to King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia, over a 10- year period with final diagnosis of deep neck infection, were reviewed. RESULTS: Eight patient's records were reviewed. Seven were less than 3-years of age. The retropharyngeal abscess was suspected clinically in 3 cases only. The most common findings were fever, neck swelling and feeding problems. The duration of symptoms and signs were so variable. The most helpful diagnostic tests were direct visualization and computerized tomography scan of the cervical area. The combination of retropharyngeal and parapharyngeal abscess was encountered in 4 patients. Cefuroxime was the drug of choice in all patients. Five patients responded to conservative management with antibiotics alone. Two cases had unusual presentation, one with subacute neck swelling, and one with severe airway compromise one week after manipulation of the tonsils by traditional therapist. CONCLUSION: High index of suspicion is warranted in such rare and life threatening disease. Special attention should be directed to the parapharyngeal entity, which was not suspected clinically in any case. The use of traditional medicine could have serious consequences in some patients.