ABSTRACT
Apophysomyces elegans is an uncommon human pathogen that causes deeply invasive infections in immunocompromised patients and cutaneous infection in immunocompetent patients. We report the development of severe deep soft tissue zygomycosis caused by A. elegans in an otherwise healthy child after trauma. She was successfully treated with surgical debridements and antifungal therapy with liposomal amphotericin B. A review of the literature indicates that zygomycosis caused by A. elegans is associated with traumatic inoculation.
Subject(s)
Fasciitis, Necrotizing/diagnosis , Fasciitis, Necrotizing/therapy , Mucormycosis/diagnosis , Mucormycosis/therapy , Phycomyces/isolation & purification , Accidents, Traffic , Anti-Bacterial Agents , Antifungal Agents/therapeutic use , Child , Combined Modality Therapy , Debridement/methods , Drug Therapy, Combination/therapeutic use , Fasciitis, Necrotizing/etiology , Female , Follow-Up Studies , Humans , Multiple Trauma/complications , Multiple Trauma/diagnosis , Risk Assessment , Severity of Illness Index , Treatment OutcomeABSTRACT
Group B Streptococcus can cause early onset neonatal disease. Beyond neonatal life, group B Streptococci are unusual pathogens. It can cause septicemia, epiglottis, fascitis, and endocarditis. A male Saudi child with group B endocarditis who has congenital heart disease is discussed.