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1.
Gland Surg ; 11(4): 663-676, 2022 Apr.
Article in English | MEDLINE | ID: mdl-35531107

ABSTRACT

Background: Diabetes is a significant and prevalent medical condition associated with increased comorbidities, longer hospital length of stay, and higher healthcare costs. We aimed to assess the association between diabetes mellitus and postoperative outcomes following pancreatic surgeries. Methods: Records for patients with major elective pancreatic surgeries were retrieved retrospectively from the Nationwide Readmission Database (2010-2014). Association of diabetic status with postoperative complications, in-hospital mortality, length of stay (LOS), readmission rate, and hospital costs were investigated. Logistic regression and decision tree analyses were employed to predict adverse outcomes. Results: A total of 8,401 patients who had pancreatic surgery were included. They were categorized according to their diabetic diagnosis. Results showed that diabetic patients had a higher risk of postoperative complications compared to non-diabetics (OR: 1.27, 95% CI: 1.08-1.49, P=0.003). Bleeding and renal complications were the most significant. Uncontrolled diabetes significantly required a longer hospital stay (9.17±4.28 vs. 8.03±4.96 days, P=0.001), and incurred higher hospital costs ($34,171.04±$20,846.61 vs. $28,182.21±$24,070.27, P=0.001). After multivariate regression, no association was found with in-hospital mortality or readmission rates; however, diabetic patients' length of stay during readmission was increased at 30- and 90-day readmissions (P=0.004 and 0.007, respectively). Conclusions: Among patients who underwent pancreatic surgery, those with diabetes had a higher rate of postoperative complications compared to non-diabetics. Additionally, diabetic patients had higher hospital charges and costs during primary admission. Initial analysis of patients with diabetes showed they had higher rates of 30- and 90-day readmissions, though this did not maintain significance after regression analysis. Exploring the mechanisms underlying this finding would aid in preventing postoperative complications and reducing healthcare costs.

2.
Laryngoscope ; 128 Suppl 3: S18-S27, 2018 10.
Article in English | MEDLINE | ID: mdl-30291765

ABSTRACT

The purpose of this publication was to inform surgeons as to the modern state-of-the-art evidence-based guidelines for management of the recurrent laryngeal nerve invaded by malignancy through blending the domains of 1) surgical intraoperative information, 2) preoperative glottic function, and 3) intraoperative real-time electrophysiologic information. These guidelines generated by the International Neural Monitoring Study Group (INMSG) are envisioned to assist the clinical decision-making process involved in recurrent laryngeal nerve management during thyroid surgery by incorporating the important information domains of not only gross surgical findings but also intraoperative recurrent laryngeal nerve functional status and preoperative laryngoscopy findings. These guidelines are presented mainly through algorithmic workflow diagrams for convenience and the ease of application. These guidelines are published in conjunction with the INMSG Guidelines Part I: Staging Bilateral Thyroid Surgery With Monitoring Loss of Signal. Level of Evidence: 5 Laryngoscope, 128:S18-S27, 2018.


Subject(s)
Intraoperative Neurophysiological Monitoring/standards , Recurrent Laryngeal Nerve/surgery , Thyroid Neoplasms/surgery , Thyroidectomy/standards , Vocal Cord Paralysis/prevention & control , Humans , Intraoperative Neurophysiological Monitoring/methods , Larynx/pathology , Larynx/physiopathology , Neoplasm Invasiveness , Recurrent Laryngeal Nerve/physiopathology , Recurrent Laryngeal Nerve Injuries/etiology , Recurrent Laryngeal Nerve Injuries/prevention & control , Thyroid Neoplasms/pathology , Thyroid Neoplasms/physiopathology , Thyroidectomy/adverse effects , Thyroidectomy/methods , Vocal Cord Paralysis/etiology
3.
Laryngoscope ; 128 Suppl 3: S1-S17, 2018 10.
Article in English | MEDLINE | ID: mdl-30289983

ABSTRACT

This publication offers modern, state-of-the-art International Neural Monitoring Study Group (INMSG) guidelines based on a detailed review of the recent monitoring literature. The guidelines outline evidence-based definitions of adverse electrophysiologic events, especially loss of signal, and their incorporation in surgical strategy. These recommendations are designed to reduce technique variations, enhance the quality of neural monitoring, and assist surgeons in the clinical decision-making process involved in surgical management of recurrent laryngeal nerve. The guidelines are published in conjunction with the INMSG Guidelines Part II, Optimal Recurrent Laryngeal Nerve Management for Invasive Thyroid Cancer-Incorporation of Surgical, Laryngeal, and Neural Electrophysiologic Data. Laryngoscope, 128:S1-S17, 2018.


Subject(s)
Intraoperative Complications/prevention & control , Intraoperative Neurophysiological Monitoring/standards , Recurrent Laryngeal Nerve Injuries/prevention & control , Recurrent Laryngeal Nerve/surgery , Thyroidectomy/standards , Vocal Cord Paralysis/prevention & control , Humans , Intraoperative Complications/etiology , Intraoperative Neurophysiological Monitoring/methods , Recurrent Laryngeal Nerve Injuries/etiology , Thyroid Gland/innervation , Thyroid Gland/surgery , Thyroidectomy/adverse effects , Thyroidectomy/methods , Vocal Cord Paralysis/etiology
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