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Annu Int Conf IEEE Eng Med Biol Soc ; 2019: 2921-2924, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31946502

ABSTRACT

Many biological tissues inside the human body exhibit highly anisotropic diffusion properties; for example, tissues of the nervous system and white matter in the brain. Here, we present an improved stochastic molecular communication framework to model interaction between bionanomachines in three-dimensional (3D) anisotropic brain micro-environment. The results obtained using stochastic particle-based simulation model are validated with analytical expressions. We also derive expressions for peak amplitude and peak time for the received molecular signal. The results demonstrate that the channel impulse response in anisotropic biological media depends significantly on the diffusion tensor as well as on the locations of the nanomachines.


Subject(s)
Brain/physiology , Diffusion Tensor Imaging , White Matter/physiology , Anisotropy , Diffusion , Humans , Models, Theoretical
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